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Protein

DNA replication and repair protein RecF

Gene

recF

Organism
Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi50 – 57ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA damage, DNA repairUniRule annotation, DNA replicationUniRule annotationSAAS annotation, SOS responseUniRule annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciMSIL395965:G1GUA-3302-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA replication and repair protein RecFUniRule annotationSAAS annotation
Gene namesi
Name:recFUniRule annotation
Ordered Locus Names:Msil_3222Imported
OrganismiMethylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2)Imported
Taxonomic identifieri395965 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBeijerinckiaceaeMethylocella
Proteomesi
  • UP000002257 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi395965.Msil_3222

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 74AAA_23InterPro annotationAdd BLAST50

Sequence similaritiesi

Belongs to the RecF family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105C3X Bacteria
COG1195 LUCA
HOGENOMiHOG000269558
KOiK03629
OMAiGQQKSFL
OrthoDBiPOG091H00U7

Family and domain databases

HAMAPiMF_00365 RecF, 1 hit
InterProiView protein in InterPro
IPR001238 DNA-binding_RecF
IPR018078 DNA-binding_RecF_CS
IPR027417 P-loop_NTPase
IPR038729 Rad50/SbcC_AAA
PANTHERiPTHR32182:SF0 PTHR32182:SF0, 1 hit
PfamiView protein in Pfam
PF13476 AAA_23, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits
TIGRFAMsiTIGR00611 recf, 1 hit
PROSITEiView protein in PROSITE
PS00617 RECF_1, 1 hit

Sequencei

Sequence statusi: Complete.

B8EQB6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQTEALATES SPAPPAKQAR RGVRRLTLAD FRSYASLDME ILAQTVVLTG
60 70 80 90 100
DNGAGKTNVL EALSLLTPGR GLRRAELSDC ARNFGGGGFA VSIEIDAEGG
110 120 130 140 150
RLQLGTGVEP NGGAALARKF RIDREPAPSI RAFCDHIRVV WLTPAMDGLF
160 170 180 190 200
VGSPGDRRRF LDRLVLSLDA DHGARVNALE RALRSRNRLL EERGAGNERL
210 220 230 240 250
WLDAVEREVA ELAIAVAAAR FETVSKLAAL IAQAGPETEG GFPLAELSLD
260 270 280 290 300
GDIDRLIETR PALEAEDEYR KILRDNRGRD AAAGRTLIGP QSSDLAVRHA
310 320 330 340 350
RKQAAASHSS TGEQKALLVG LILAQARLIK AMSGLAPLVL LDEIAAHFDP
360 370 380 390
KRRAALYELL GALGAQVWLT GADPSAFAEL EGKAQMLQVT PGAIRELH
Length:398
Mass (Da):42,643
Last modified:March 3, 2009 - v1
Checksum:i66E5526AD4C1B8A0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001280 Genomic DNA Translation: ACK52129.1
RefSeqiWP_012592198.1, NC_011666.1

Genome annotation databases

EnsemblBacteriaiACK52129; ACK52129; Msil_3222
KEGGimsl:Msil_3222

Similar proteinsi

Entry informationi

Entry nameiB8EQB6_METSB
AccessioniPrimary (citable) accession number: B8EQB6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health