B8EPV2 (B8EPV2_METSB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Urease accessory protein UreD HAMAP MF_01384

Gene names

Name:	ureD HAMAP MF_01384
Ordered Locus Names:	Msil_2014

Organism

Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906) [Complete proteome] [HAMAP] EMBL ACK50956.1

Taxonomic identifier

395965 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Beijerinckiaceae › Methylocella

Protein attributes

Sequence length	282 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter By similarity. HAMAP MF_01384
Subunit structure	UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel By similarity. HAMAP MF_01384
Subcellular location	Cytoplasm By similarity HAMAP MF_01384.
Sequence similarities	Belongs to the UreD family. HAMAP MF_01384

Ontologies

Keywords
Biological process	Nickel insertion HAMAP MF_01384
Cellular component	Cytoplasm HAMAP MF_01384
Molecular function	Chaperone HAMAP MF_01384
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	nickel cation binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8EPV2 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 67B31462A4269AA3	FASTA	282	30,368
	10 20 30 40 50 60 MNFVEPGRRA IGTSAPLQRS EGGARLSARW ISGGTRLHAL RQTSPCRIFF PRRNDPAVLE 70 80 90 100 110 120 AILVNSSGGL VEGDRISISV EVGCGATVIM RTQAAEKIYR SLTRETVIAT ELVIGRGGFL 130 140 150 160 170 180 DWRPQEAILF DGARLSRSQS FVVEADSRFL SGEVVIFGRI ARGETFAHGE LRDAVTVRCG 190 200 210 220 230 240 GRLLFADRLR LGGEVAALRH ARFGLGGSAG LASILYFGPG AARLLPFARA RAEQRCGGAT 250 260 270 280 LVNGILLARF LHPDETRLRG AAAEFLDELS LEIATTHSRD AA

References

[1]

"Complete sequence of Methylocella silvestris BL2." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Forester B., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Dunfield P.F., Dedysh S.N., Liesack W. , Stott M.B., Smirnova A.V., Alam M., Chen Y., Murrell J.C., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BL2 / DSM 15510 / NCIMB 13906.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001280 Genomic DNA. Translation: ACK50956.1.
RefSeq	YP_002362318.1. NC_011666.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B8EPV2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7094212.
GenomeReviews	Gene locus Msil_2014 in contig CP001280_GR.
KEGG	msl:Msil_2014.
PATRIC	22599627. VBIMetSil55537_2180.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG711156.
OMA	QETILFD.
Family and domain databases
HAMAP	MF_01384. UreD. [Tree]
InterPro	IPR002669. UreD. [Graphical view]
KO	K03190.
Pfam	PF01774. UreD. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8EPV2_METSB

Accession

Primary (citable) accession number: B8EPV2

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)