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B8EPF5 (B8EPF5_METSB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855
Short name=FBPase class 1 HAMAP MF_01855
EC=3.1.3.11 HAMAP MF_01855
Alternative name(s):
D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 HAMAP MF_01855
Gene names
Name:fbp HAMAP MF_01855
Ordered Locus Names:Msil_1191
OrganismMethylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906) [Complete proteome] [HAMAP] EMBL ACK50160.1
Taxonomic identifier395965 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Beijerinckiaceae › Methylocella

Protein attributes

Sequence length352 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity. HAMAP MF_01855

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity. HAMAP MF_01855

Subcellular location

Cytoplasm By similarity HAMAP MF_01855.

Sequence similarities

Belongs to the FBPase class 1 family. HAMAP MF_01855

Ontologies

Keywords
   Biological processCarbohydrate metabolism HAMAP MF_01855
   Cellular componentCytoplasm HAMAP MF_01855
   LigandMagnesium HAMAP MF_01855
Metal-binding HAMAP MF_01855
   Molecular functionHydrolase HAMAP MF_01855
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processcarbohydrate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region116 – 1194Substrate binding By similarity HAMAP MF_01855

Sites

Metal binding941Magnesium 1 By similarity HAMAP MF_01855
Metal binding1131Magnesium 1 By similarity HAMAP MF_01855
Metal binding1131Magnesium 2 By similarity HAMAP MF_01855
Metal binding1151Magnesium 1; via carbonyl oxygen By similarity HAMAP MF_01855
Metal binding1161Magnesium 2 By similarity HAMAP MF_01855
Metal binding2801Magnesium 2 By similarity HAMAP MF_01855
Binding site2081Substrate By similarity HAMAP MF_01855

Sequences

Sequence LengthMass (Da)Tools
B8EPF5 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 71AF14A62498C8EB

FASTA35237,974
        10         20         30         40         50         60 
MPRISGAEEL KAYLGRVVGA DARLEAAAAT LGEIAAASVK MSDLIGLGRL YGHLGDSRGS 

        70         80         90        100        110        120 
TNSDGDVQKE LDVLADEMFV EALRRAPVYG VVSEELKEAL LLNPNAPIVV SMDPLDGSSN 

       130        140        150        160        170        180 
IDANVSIGTI FSLLPTLPEA RSLEAHFLQK GRAQIAAGFV IYGPQTSMVF AIGASPVEIF 

       190        200        210        220        230        240 
TLDRNDGQFY HAATVGPIPK ESSEYAVNSS NYRHWEPSIR AFIEDCARGL DGPMKRNYNM 

       250        260        270        280        290        300 
RWVASLVAEA YRILLRGGIF LYPGDQRPGY SDGRLRLLYE GAPVAFLIER AGGVATDGLS 

       310        320        330        340        350 
PLLDIEPTAI HQRAPLVFGS ADPVRLVARY RSDPKVSAER APLFGGRGLM RD

« Hide

References

[1]"Complete sequence of Methylocella silvestris BL2."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Forester B., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Dunfield P.F., Dedysh S.N., Liesack W. expand/collapse author list , Stott M.B., Smirnova A.V., Alam M., Chen Y., Murrell J.C., Richardson P.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BL2 / DSM 15510 / NCIMB 13906.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001280 Genomic DNA. Translation: ACK50160.1.
RefSeqYP_002361522.1. NC_011666.1.

3D structure databases

ProteinModelPortalB8EPF5.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8EPF5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7092264.
GenomeReviewsGene locus Msil_1191 in contig CP001280_GR.
KEGGmsl:Msil_1191.
PATRIC22597867. VBIMetSil55537_1312.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG731261.
OMAHWEAPVQ.

Family and domain databases

HAMAPMF_01855. FBPase_class1.
[Tree]
InterProIPR000146. FBPase_class-1/SBPase.
IPR020548. Fructose_bisphosphatase_AS.
[Graphical view]
KOK03841.
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PIRSFPIRSF000904. FBPtase_SBPase. 1 hit.
PRINTSPR00115. F16BPHPHTASE.
PROSITEPS00124. FBPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8EPF5_METSB
AccessionPrimary (citable) accession number: B8EPF5
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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