B8EN59 (GLGA_METSB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	Msil_0213

Organism

Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906) [Complete proteome] [HAMAP]

Taxonomic identifier

395965 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Beijerinckiaceae › Methylocella

Protein attributes

Sequence length	483 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	starch synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 483	483	Glycogen synthase HAMAP MF_00484		PRO_1000135653
Sites
	Binding site	18	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	B8EN59 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: B317FA4AA79A2033	FASTA	483	51,456
	10 20 30 40 50 60 MSEISVLAIV SEIFPLIKTG GLADVAGALP AALAGEGIEV ATLVPGYPAV MAQIEYAETV 70 80 90 100 110 120 IDARPLYGAP ARVLRGSAAG LDLFVLDAPH LYDRPGNPYL LPDGRDFPDN PFRFAALCQT 130 140 150 160 170 180 GSALGFGAAP GFLPDIVHAH DWQAGLAAAY LHYDGRERPG TVATIHNLAF QGKYPAELLG 190 200 210 220 230 240 ALGLPPQAFS LEGVEYYGTI GFLKAALALS DRITTVSPTY AAEIRTPEHG MGLDGLLRTR 250 260 270 280 290 300 AERLIGILNG IDDEVWDPSS DPLITEPFDV ETLARRPANK AALQDKFGLD PDPGALLLGV 310 320 330 340 350 360 VSRLSWQKGL DLLLANLDLL ERLGVQLAVL GSGEPELVRQ LLEAAEARPG RVGAVIGYDE 370 380 390 400 410 420 AIAHRIQAGA DAIVIPSRFE PCGLTQLCAL RYGALPIVAR VGGLADTIID ANEMALASGI 430 440 450 460 470 480 GTGLQFSPPT ADMLGATLER AARLWAEPEI WDELIENGML TDVSWRRPAA LYAKLFRDLV RER

References

[1]

"Complete sequence of Methylocella silvestris BL2." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Forester B., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Dunfield P.F., Dedysh S.N., Liesack W. , Stott M.B., Smirnova A.V., Alam M., Chen Y., Murrell J.C., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BL2 / DSM 15510 / NCIMB 13906.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001280 Genomic DNA. Translation: ACK49194.1.
RefSeq	YP_002360556.1. NC_011666.1.
3D structure databases
ProteinModelPortal	B8EN59.
ModBase	Search...
Protein-protein interaction databases
STRING	B8EN59.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7090530.
GenomeReviews	Gene locus Msil_0213 in contig CP001280_GR.
KEGG	msl:Msil_0213.
PATRIC	22595671. VBIMetSil55537_0233.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG596384.
OMA	DWQAGLV.
ProtClustDB	PRK14099.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth. [Tree]
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
KO	K00703.
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. GlgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_METSB

Accession

Primary (citable) accession number: B8EN59

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program