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Protein

Glycogen synthase

Gene

glgA

Organism
Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathway: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei18 – 181ADP-glucoseUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciMSIL395965:GCND-216-MONOMER.
UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:Msil_0213
OrganismiMethylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)
Taxonomic identifieri395965 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBeijerinckiaceaeMethylocella
ProteomesiUP000002257 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 483483Glycogen synthasePRO_1000135653Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi395965.Msil_0213.

Structurei

3D structure databases

ProteinModelPortaliB8EN59.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OMAiPAYDEAM.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

B8EN59-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEISVLAIV SEIFPLIKTG GLADVAGALP AALAGEGIEV ATLVPGYPAV
60 70 80 90 100
MAQIEYAETV IDARPLYGAP ARVLRGSAAG LDLFVLDAPH LYDRPGNPYL
110 120 130 140 150
LPDGRDFPDN PFRFAALCQT GSALGFGAAP GFLPDIVHAH DWQAGLAAAY
160 170 180 190 200
LHYDGRERPG TVATIHNLAF QGKYPAELLG ALGLPPQAFS LEGVEYYGTI
210 220 230 240 250
GFLKAALALS DRITTVSPTY AAEIRTPEHG MGLDGLLRTR AERLIGILNG
260 270 280 290 300
IDDEVWDPSS DPLITEPFDV ETLARRPANK AALQDKFGLD PDPGALLLGV
310 320 330 340 350
VSRLSWQKGL DLLLANLDLL ERLGVQLAVL GSGEPELVRQ LLEAAEARPG
360 370 380 390 400
RVGAVIGYDE AIAHRIQAGA DAIVIPSRFE PCGLTQLCAL RYGALPIVAR
410 420 430 440 450
VGGLADTIID ANEMALASGI GTGLQFSPPT ADMLGATLER AARLWAEPEI
460 470 480
WDELIENGML TDVSWRRPAA LYAKLFRDLV RER
Length:483
Mass (Da):51,456
Last modified:March 3, 2009 - v1
Checksum:iB317FA4AA79A2033
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001280 Genomic DNA. Translation: ACK49194.1.
RefSeqiWP_012589264.1. NC_011666.1.
YP_002360556.1. NC_011666.1.

Genome annotation databases

EnsemblBacteriaiACK49194; ACK49194; Msil_0213.
KEGGimsl:Msil_0213.
PATRICi22595671. VBIMetSil55537_0233.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001280 Genomic DNA. Translation: ACK49194.1.
RefSeqiWP_012589264.1. NC_011666.1.
YP_002360556.1. NC_011666.1.

3D structure databases

ProteinModelPortaliB8EN59.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi395965.Msil_0213.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK49194; ACK49194; Msil_0213.
KEGGimsl:Msil_0213.
PATRICi22595671. VBIMetSil55537_0233.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294941.
KOiK00703.
OMAiPAYDEAM.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciMSIL395965:GCND-216-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. GS/SS.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the aerobic facultative methanotroph Methylocella silvestris BL2."
    Chen Y., Crombie A., Rahman M.T., Dedysh S.N., Liesack W., Stott M.B., Alam M., Theisen A.R., Murrell J.C., Dunfield P.F.
    J. Bacteriol. 192:3840-3841(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BL2 / DSM 15510 / NCIMB 13906.

Entry informationi

Entry nameiGLGA_METSB
AccessioniPrimary (citable) accession number: B8EN59
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: June 24, 2015
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.