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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Methylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei156UniRule annotation1
Active sitei585UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciMSIL395965:G1GUA-1864-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Msil_1819Imported
OrganismiMethylocella silvestris (strain DSM 15510 / CIP 108128 / LMG 27833 / NCIMB 13906 / BL2)Imported
Taxonomic identifieri395965 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBeijerinckiaceaeMethylocella
Proteomesi
  • UP000002257 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi395965.Msil_1819

Structurei

3D structure databases

ProteinModelPortaliB8ELY3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili94 – 114Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

B8ELY3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTKVLDPISA NSASTIERPL IDDIRLLGQI LGDTIREQEG EDTFGLVEQA
60 70 80 90 100
RRLSVEFERH ADPDAELKLN ELLRSLTPQQ AMAVIRAFSY FAHLANIAED
110 120 130 140 150
RHNIRRRAAQ AAERPDEHDG GTLDKTFELL AAASITPEAV AEAIAQARVS
160 170 180 190 200
PVLTAHPTEV QRRSLLDAER AIAQLLLARE TLSGERPRKQ NEMMLRARIA
210 220 230 240 250
QLWQTRLLRY ARLSVRDEIE NSLAFYQMTF LKQIPQLYAR IEERLGSLPV
260 270 280 290 300
ASFFRMGSWI GGDRDGNPNV NAGTLELALR RQCDTALRHY LREIHELGAE
310 320 330 340 350
LSISGRLFGC AEALQELAEK SGDENPFRDD EPYRRALIGV YSRLSSTLTL
360 370 380 390 400
LTGGEALRHA VAPGEPYANA GELQADLGVI EDSLRANHGA ALVPGRLGPL
410 420 430 440 450
RRAVDVFGFH LASVDLRQSS DRHEETLKEL MSVARIVPDY SALDEDARQN
460 470 480 490 500
LLIDLLRDPR PLRVPGVTYS PRTEEELEIF EAARDARRTF GEPAVVHYII
510 520 530 540 550
SHTETVSDLL EVLALQKECG MVHGVLGEPG TSAELMVVPL FETIEDLRNA
560 570 580 590 600
ATIMRGFYAL PGVAELTRAS GAEQEIMLGY SDSNKDGGFF TSNWELYRSS
610 620 630 640 650
TALAALFKEH DGIALRLFHG RGGTVGRGGG PSYQAILAQP PGTVAGQIRL
660 670 680 690 700
TEQGEVISSK YANPEIGLLN LEALVAATIE ATLLPSAGAA PKEFLDAAEE
710 720 730 740 750
LSQASMKAFR AVIYDNPRFV DYFFTATPIA EIAELNIGSR PASRKSTRRI
760 770 780 790 800
EDLRAIPWSF SWGQARINLP GWFGFGSAVE QFVAKAPAER MALLRRMGAE
810 820 830 840 850
WPFFRALLSN MDMVLAKADM GLAGRYAELV PDQELAKSVF GSIEAEWART
860 870 880 890 900
TKALNEITGV STRLSDNPAL AGAIKHRFPY ISPLNHLQVE LLRRWRSGEH
910 920
DDKTLRSILI TINGVAAGLR NTG
Length:923
Mass (Da):101,856
Last modified:March 3, 2009 - v1
Checksum:i646551DC70F06F09
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001280 Genomic DNA Translation: ACK50764.1
RefSeqiWP_012590834.1, NC_011666.1

Genome annotation databases

EnsemblBacteriaiACK50764; ACK50764; Msil_1819
KEGGimsl:Msil_1819

Similar proteinsi

Entry informationi

Entry nameiB8ELY3_METSB
AccessioniPrimary (citable) accession number: B8ELY3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: March 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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