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Protein
Submitted name:

DNA ligase D

Gene

Msil_1736

Organism
Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. DNA ligase (ATP) activity Source: InterPro

GO - Biological processi

  1. DNA recombination Source: InterPro
  2. DNA repair Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciMSIL395965:GCND-1765-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
DNA ligase DImported
Gene namesi
Ordered Locus Names:Msil_1736Imported
OrganismiMethylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)Imported
Taxonomic identifieri395965 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBeijerinckiaceaeMethylocella
ProteomesiUP000002257: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi395965.Msil_1736.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiLELHPWN.
OrthoDBiEOG661H49.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. DNA_pol_LigD_ligase_dom.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8EKE2-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MADTKLKTYR AKRDFAQTAE PSGEAPIAAG PRRRFVIQKH AATRLHYDLR
60 70 80 90 100
LELDGVFKSW AVTKGPSLDP HDKRLAVEVE DHPLDYGDFE GVIPKGQYGG
110 120 130 140 150
GTVQLWDRGF WAPEGDKTPE QALADGDLKF TLDGQRLYGS WVLVRMKADR
160 170 180 190 200
TGGKRTNWLL IKHRDGYARD GDADALLAED RSVASGRAMA AIAAGKGKGP
210 220 230 240 250
KPFMLAGEQA ADPKAVWDSN KGLAAEARAA PKATRKKSGA ALAQMPDFLP
260 270 280 290 300
PQLCQPVERP PSGDGWVHEI KFDGYRMQLR VAGGKATLKT RKGLDWTDKF
310 320 330 340 350
AAIAAEAADF PDAIIDGEIV ALDSSGSPDF VALQAALSEQ NTDDLIFYAF
360 370 380 390 400
DLMFEGGRDL RLEPLAARKQ ALARLIAGAR LGAGALIRFV EHFETGGDAI
410 420 430 440 450
LQSACRLNLE GIVSKKRDAP YQPGRSDSWT RAKCRAGHEV VIGGWTTTEG
460 470 480 490 500
KFRSLLAGVH HGENFTYIGR IGTGFGEAKV KTLLPKLKQF AAETSPFTGP
510 520 530 540 550
SAPRKTASIH WLKPELVAEI EFAGFTGAGM VRQAAFKGLR EDKPAEEVEA
560 570 580 590 600
ETPAPPEQAA VPDPAEIQAS ARSSSDKPMA TANGKPIVMG VAISNPAKEL
610 620 630 640 650
WPADGAEAPV SKLDLARYYE AAGPWLIEHV RGRPCSLIRA PDGITGQQFF
660 670 680 690 700
QRHAMAGASN LLDLVTVSGD RAPYLQIDRV EGLAAVAQIA GLELHPWNCA
710 720 730 740 750
PGRPETPGRL IFDLDPGPDV AFEQVAAAAL EMRDRLDALG LVSFCKTTGG
760 770 780 790 800
KGLHVVTPLA VAKGSKLTWP EAKGFAQEVC RRMAADNSNA YLLNMSKKLR
810 820 830 840 850
AGRIFLDYLR NDRMSTAVAP LSPRARPGAT VSMPLNWSEA TNSLDPKAFT
860 870 880
IRTSVGLLDK SKAWADYDSG ARPLEAAIKR LGRAKAAA
Length:888
Mass (Da):95,708
Last modified:March 3, 2009 - v1
Checksum:i41303A7E819AC29E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001280 Genomic DNA. Translation: ACK50682.1.
RefSeqiYP_002362044.1. NC_011666.1.

Genome annotation databases

EnsemblBacteriaiACK50682; ACK50682; Msil_1736.
GeneIDi7090848.
KEGGimsl:Msil_1736.
PATRICi22599011. VBIMetSil55537_1879.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001280 Genomic DNA. Translation: ACK50682.1.
RefSeqiYP_002362044.1. NC_011666.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi395965.Msil_1736.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK50682; ACK50682; Msil_1736.
GeneIDi7090848.
KEGGimsl:Msil_1736.
PATRICi22599011. VBIMetSil55537_1879.

Phylogenomic databases

eggNOGiCOG3285.
HOGENOMiHOG000222509.
KOiK01971.
OMAiLELHPWN.
OrthoDBiEOG661H49.

Enzyme and pathway databases

BioCyciMSIL395965:GCND-1765-MONOMER.

Family and domain databases

Gene3Di2.40.50.140. 1 hit.
InterProiIPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR014146. DNA_pol_LigD_ligase_dom.
IPR014144. LigD_PE_domain.
IPR014145. LigD_pol.
IPR012340. NA-bd_OB-fold.
IPR014143. NHEJ_ligase_prk.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF13298. LigD_N. 1 hit.
[Graphical view]
SUPFAMiSSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR02777. LigD_PE_dom. 1 hit.
TIGR02778. ligD_pol. 1 hit.
TIGR02779. NHEJ_ligase_lig. 1 hit.
TIGR02776. NHEJ_ligase_prk. 1 hit.
PROSITEiPS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the aerobic facultative methanotroph Methylocella silvestris BL2."
    Chen Y., Crombie A., Rahman M.T., Dedysh S.N., Liesack W., Stott M.B., Alam M., Theisen A.R., Murrell J.C., Dunfield P.F.
    J. Bacteriol. 192:3840-3841(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BL2 / DSM 15510 / NCIMB 13906Imported.

Entry informationi

Entry nameiB8EKE2_METSB
AccessioniPrimary (citable) accession number: B8EKE2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: January 7, 2015
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.