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B8EKC5

- B8EKC5_METSB

UniProt

B8EKC5 - B8EKC5_METSB

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Protein
Phosphoenolpyruvate carboxylase
Gene
ppc, Msil_1718
Organism
Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity.UniRule annotationSAAS annotations

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotations

Cofactori

Magnesium By similarity.UniRule annotationSAAS annotations

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei141 – 1411 By similarityUniRule annotation
Active sitei578 – 5781 By similarityUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotationsImported

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotations

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotations, PyruvateImported

Enzyme and pathway databases

BioCyciMSIL395965:GCND-1747-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Msil_1718Imported
OrganismiMethylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)Imported
Taxonomic identifieri395965 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBeijerinckiaceaeMethylocella
ProteomesiUP000002257: Chromosome

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi395965.Msil_1718.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiNLMIASL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8EKC5-1 [UniParc]FASTAAdd to Basket

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MTELQAERRL EQALSVVDVS DGAPSGERIA AILYQLLLEV VQRHHPEIAP    50
VLSGETVLQN AAPEVLSRVF QAHGIWFQLL SIVEQDAAMG ERRRTERELG 100
EQAVPGTFAN VIAKAAKLGV PAADIAEKLG RTRVRPVITA HPTEAKRVTV 150
LEKHRRIYRL LVELEQPRWT GRERSGIIDQ LRDEIELLWM TGELRLEKPS 200
VEQEIAWGLH FFHETLFEGV PELLKKFDRA LKRFYPSENF ALTQFFQFGS 250
WIGGDRDGNP FVTNKVTRRA LRENAKASLR FYEQRLFNLM KSLSISERAL 300
PPPSGFREAL NRALSDSGDG AGIALRNPGE PYRQFLYCAH AKVKATLALY 350
EGERTPGPHY ISADDLISDL AVTEQALAES GSVGLAQDLV RPVRFAVEAF 400
RFRTQRLDLR ENTTKLTSTL QALWRAMHTE ADGEPPAVES DEWKAWILAE 450
LARPRIGPPV YRALPPEAEE TLGMFKLARD RDEEFDREAF GSFVLSMTRS 500
AADVLGAYLL AKEADLYHDA TRVEACTLSI TPLFETITDL RAAPQIMREL 550
LSLPLVRRSA RMQGGVQEVM IGYSDSNKDG GFLSSNWELA KAQDKLAKIG 600
AEAGIPISFF HGRGGSVSRG GAPTAQAIAA QPAGSIQGRL RVTEQGEVVS 650
FKYANRGTAA FQMEMLGSSV FEHTLTLERA APALRAEFEE AMEALSGASH 700
AAYANFINHP DLLTYFQSAS PLDEISMLNI GSRPARRFGA RTLSDLRAIP 750
WVFAWAQNRH VITGWYGVGS GIASFLDVRK ERGLTLLKRM FAESDLFRMI 800
VGEVEKTLGM VDLDIAREYA GLVYDDDVRE TIFGMIEAEY RLTRANILKI 850
TGEEEIAQRF PAYRSRLETR LKTINKVNRE QVELLRNFRA STNELSKEAF 900
KSNLLLSINC ISSGLGATG 919
Length:919
Mass (Da):102,507
Last modified:March 3, 2009 - v1
Checksum:iDB7EC507D4F1DB02
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001280 Genomic DNA. Translation: ACK50665.1.
RefSeqiYP_002362027.1. NC_011666.1.

Genome annotation databases

EnsemblBacteriaiACK50665; ACK50665; Msil_1718.
GeneIDi7093178.
KEGGimsl:Msil_1718.
PATRICi22598975. VBIMetSil55537_1861.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001280 Genomic DNA. Translation: ACK50665.1 .
RefSeqi YP_002362027.1. NC_011666.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 395965.Msil_1718.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACK50665 ; ACK50665 ; Msil_1718 .
GeneIDi 7093178.
KEGGi msl:Msil_1718.
PATRICi 22598975. VBIMetSil55537_1861.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238647.
KOi K01595.
OMAi NLMIASL.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci MSIL395965:GCND-1747-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00393. PEPCASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the aerobic facultative methanotroph Methylocella silvestris BL2."
    Chen Y., Crombie A., Rahman M.T., Dedysh S.N., Liesack W., Stott M.B., Alam M., Theisen A.R., Murrell J.C., Dunfield P.F.
    J. Bacteriol. 192:3840-3841(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BL2 / DSM 15510 / NCIMB 13906.

Entry informationi

Entry nameiB8EKC5_METSB
AccessioniPrimary (citable) accession number: B8EKC5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 11, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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