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B8EKC5

- B8EKC5_METSB

UniProt

B8EKC5 - B8EKC5_METSB

Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

    Cofactori

    Magnesium.UniRule annotationSAAS annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei141 – 1411UniRule annotation
    Active sitei578 – 5781UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotationImported

    Keywords - Biological processi

    Carbon dioxide fixationUniRule annotationSAAS annotation

    Keywords - Ligandi

    MagnesiumUniRule annotationSAAS annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciMSIL395965:GCND-1747-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcUniRule annotation
    Ordered Locus Names:Msil_1718Imported
    OrganismiMethylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)Imported
    Taxonomic identifieri395965 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBeijerinckiaceaeMethylocella
    ProteomesiUP000002257: Chromosome

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi395965.Msil_1718.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 1 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2352.
    HOGENOMiHOG000238647.
    KOiK01595.
    OMAiNLMIASL.
    OrthoDBiEOG6TJ7T8.

    Family and domain databases

    HAMAPiMF_00595. PEPcase_type1.
    InterProiIPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF00311. PEPcase. 1 hit.
    [Graphical view]
    PRINTSiPR00150. PEPCARBXLASE.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    PROSITEiPS00393. PEPCASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8EKC5-1 [UniParc]FASTAAdd to Basket

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    MTELQAERRL EQALSVVDVS DGAPSGERIA AILYQLLLEV VQRHHPEIAP    50
    VLSGETVLQN AAPEVLSRVF QAHGIWFQLL SIVEQDAAMG ERRRTERELG 100
    EQAVPGTFAN VIAKAAKLGV PAADIAEKLG RTRVRPVITA HPTEAKRVTV 150
    LEKHRRIYRL LVELEQPRWT GRERSGIIDQ LRDEIELLWM TGELRLEKPS 200
    VEQEIAWGLH FFHETLFEGV PELLKKFDRA LKRFYPSENF ALTQFFQFGS 250
    WIGGDRDGNP FVTNKVTRRA LRENAKASLR FYEQRLFNLM KSLSISERAL 300
    PPPSGFREAL NRALSDSGDG AGIALRNPGE PYRQFLYCAH AKVKATLALY 350
    EGERTPGPHY ISADDLISDL AVTEQALAES GSVGLAQDLV RPVRFAVEAF 400
    RFRTQRLDLR ENTTKLTSTL QALWRAMHTE ADGEPPAVES DEWKAWILAE 450
    LARPRIGPPV YRALPPEAEE TLGMFKLARD RDEEFDREAF GSFVLSMTRS 500
    AADVLGAYLL AKEADLYHDA TRVEACTLSI TPLFETITDL RAAPQIMREL 550
    LSLPLVRRSA RMQGGVQEVM IGYSDSNKDG GFLSSNWELA KAQDKLAKIG 600
    AEAGIPISFF HGRGGSVSRG GAPTAQAIAA QPAGSIQGRL RVTEQGEVVS 650
    FKYANRGTAA FQMEMLGSSV FEHTLTLERA APALRAEFEE AMEALSGASH 700
    AAYANFINHP DLLTYFQSAS PLDEISMLNI GSRPARRFGA RTLSDLRAIP 750
    WVFAWAQNRH VITGWYGVGS GIASFLDVRK ERGLTLLKRM FAESDLFRMI 800
    VGEVEKTLGM VDLDIAREYA GLVYDDDVRE TIFGMIEAEY RLTRANILKI 850
    TGEEEIAQRF PAYRSRLETR LKTINKVNRE QVELLRNFRA STNELSKEAF 900
    KSNLLLSINC ISSGLGATG 919
    Length:919
    Mass (Da):102,507
    Last modified:March 3, 2009 - v1
    Checksum:iDB7EC507D4F1DB02
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001280 Genomic DNA. Translation: ACK50665.1.
    RefSeqiYP_002362027.1. NC_011666.1.

    Genome annotation databases

    EnsemblBacteriaiACK50665; ACK50665; Msil_1718.
    GeneIDi7093178.
    KEGGimsl:Msil_1718.
    PATRICi22598975. VBIMetSil55537_1861.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001280 Genomic DNA. Translation: ACK50665.1 .
    RefSeqi YP_002362027.1. NC_011666.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 395965.Msil_1718.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACK50665 ; ACK50665 ; Msil_1718 .
    GeneIDi 7093178.
    KEGGi msl:Msil_1718.
    PATRICi 22598975. VBIMetSil55537_1861.

    Phylogenomic databases

    eggNOGi COG2352.
    HOGENOMi HOG000238647.
    KOi K01595.
    OMAi NLMIASL.
    OrthoDBi EOG6TJ7T8.

    Enzyme and pathway databases

    BioCyci MSIL395965:GCND-1747-MONOMER.

    Family and domain databases

    HAMAPi MF_00595. PEPcase_type1.
    InterProi IPR021135. PEP_COase.
    IPR018129. PEP_COase_AS.
    IPR022805. PEP_COase_bac/pln-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF00311. PEPcase. 1 hit.
    [Graphical view ]
    PRINTSi PR00150. PEPCARBXLASE.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    PROSITEi PS00393. PEPCASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the aerobic facultative methanotroph Methylocella silvestris BL2."
      Chen Y., Crombie A., Rahman M.T., Dedysh S.N., Liesack W., Stott M.B., Alam M., Theisen A.R., Murrell J.C., Dunfield P.F.
      J. Bacteriol. 192:3840-3841(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BL2 / DSM 15510 / NCIMB 13906Imported.

    Entry informationi

    Entry nameiB8EKC5_METSB
    AccessioniPrimary (citable) accession number: B8EKC5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3