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B8EK14

- B8EK14_METSB

UniProt

B8EK14 - B8EK14_METSB

Protein

Signal peptidase I

Gene

Msil_0992

Organism
Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.UniRule annotation

    GO - Molecular functioni

    1. serine-type peptidase activity Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, ProteaseUniRule annotation

    Enzyme and pathway databases

    BioCyciMSIL395965:GCND-1014-MONOMER.

    Protein family/group databases

    MEROPSiS26.001.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Signal peptidase IUniRule annotation (EC:3.4.21.89UniRule annotation)
    Gene namesi
    Ordered Locus Names:Msil_0992Imported
    OrganismiMethylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906)Imported
    Taxonomic identifieri395965 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBeijerinckiaceaeMethylocella
    ProteomesiUP000002257: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: InterPro

    Interactioni

    Protein-protein interaction databases

    STRINGi395965.Msil_0992.

    Structurei

    3D structure databases

    ProteinModelPortaliB8EK14.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase S26 family.

    Phylogenomic databases

    eggNOGiCOG0681.
    HOGENOMiHOG000003673.
    KOiK03100.
    OMAiLYFWTWR.
    OrthoDBiEOG6KDKTM.

    Family and domain databases

    Gene3Di2.10.109.10. 2 hits.
    InterProiIPR000223. Pept_S26A_signal_pept_1.
    IPR019758. Pept_S26A_signal_pept_1_CS.
    IPR019757. Pept_S26A_signal_pept_1_Lys-AS.
    IPR019756. Pept_S26A_signal_pept_1_Ser-AS.
    IPR028360. Peptidase_S24/S26_b-rbn.
    IPR019759. Peptidase_S24_S26.
    IPR015927. Peptidase_S24_S26A/B/C.
    [Graphical view]
    PANTHERiPTHR12383. PTHR12383. 1 hit.
    PfamiPF00717. Peptidase_S24. 1 hit.
    [Graphical view]
    PRINTSiPR00727. LEADERPTASE.
    SUPFAMiSSF51306. SSF51306. 1 hit.
    TIGRFAMsiTIGR02227. sigpep_I_bact. 1 hit.
    PROSITEiPS00501. SPASE_I_1. 1 hit.
    PS00760. SPASE_I_2. 1 hit.
    PS00761. SPASE_I_3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8EK14-1 [UniParc]FASTAAdd to Basket

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    MTEPVRLNEK GAQVKPRAEG GIGETVKVVL QALLIALVVR TFLFQPFNIP    50
    SGSMIPTLLI GDYLFVSKYA YGYSRHSIPF SPDLFHGRLF SSPPKRGDVA 100
    VFKLPRDGQT DYIKRVIGLP GDKIQMKDGR LFINDELVPR EPIAKAHTED 150
    FYGRETDVPT YEETLPGGVK HTIIEIQGDT GFNDNTQAFV VPPDHYFMMG 200
    DNRDNSTDSR VSPDQGGVGY VPFDNFVGRA ELIFFSVGKG APAWAFWEWP 250
    WTVRWDRMLK PVH 263
    Length:263
    Mass (Da):29,607
    Last modified:March 3, 2009 - v1
    Checksum:i60B6CB1916571641
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001280 Genomic DNA. Translation: ACK49961.1.
    RefSeqiYP_002361323.1. NC_011666.1.

    Genome annotation databases

    EnsemblBacteriaiACK49961; ACK49961; Msil_0992.
    GeneIDi7093671.
    KEGGimsl:Msil_0992.
    PATRICi22597417. VBIMetSil55537_1089.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001280 Genomic DNA. Translation: ACK49961.1 .
    RefSeqi YP_002361323.1. NC_011666.1.

    3D structure databases

    ProteinModelPortali B8EK14.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 395965.Msil_0992.

    Protein family/group databases

    MEROPSi S26.001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACK49961 ; ACK49961 ; Msil_0992 .
    GeneIDi 7093671.
    KEGGi msl:Msil_0992.
    PATRICi 22597417. VBIMetSil55537_1089.

    Phylogenomic databases

    eggNOGi COG0681.
    HOGENOMi HOG000003673.
    KOi K03100.
    OMAi LYFWTWR.
    OrthoDBi EOG6KDKTM.

    Enzyme and pathway databases

    BioCyci MSIL395965:GCND-1014-MONOMER.

    Family and domain databases

    Gene3Di 2.10.109.10. 2 hits.
    InterProi IPR000223. Pept_S26A_signal_pept_1.
    IPR019758. Pept_S26A_signal_pept_1_CS.
    IPR019757. Pept_S26A_signal_pept_1_Lys-AS.
    IPR019756. Pept_S26A_signal_pept_1_Ser-AS.
    IPR028360. Peptidase_S24/S26_b-rbn.
    IPR019759. Peptidase_S24_S26.
    IPR015927. Peptidase_S24_S26A/B/C.
    [Graphical view ]
    PANTHERi PTHR12383. PTHR12383. 1 hit.
    Pfami PF00717. Peptidase_S24. 1 hit.
    [Graphical view ]
    PRINTSi PR00727. LEADERPTASE.
    SUPFAMi SSF51306. SSF51306. 1 hit.
    TIGRFAMsi TIGR02227. sigpep_I_bact. 1 hit.
    PROSITEi PS00501. SPASE_I_1. 1 hit.
    PS00760. SPASE_I_2. 1 hit.
    PS00761. SPASE_I_3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the aerobic facultative methanotroph Methylocella silvestris BL2."
      Chen Y., Crombie A., Rahman M.T., Dedysh S.N., Liesack W., Stott M.B., Alam M., Theisen A.R., Murrell J.C., Dunfield P.F.
      J. Bacteriol. 192:3840-3841(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: BL2 / DSM 15510 / NCIMB 13906Imported.

    Entry informationi

    Entry nameiB8EK14_METSB
    AccessioniPrimary (citable) accession number: B8EK14
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3