B8EK14 (B8EK14_METSB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Signal peptidase I RuleBase RU003993
EC=3.4.21.89 RuleBase RU003993

Gene names

Ordered Locus Names:

Msil_0992

Organism

Methylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906) [Complete proteome] [HAMAP] EMBL ACK49961.1

Taxonomic identifier

395965 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Beijerinckiaceae › Methylocella › Methylocella silvestris

Protein attributes

Sequence length	263 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins. RuleBase RU003993
Sequence similarities	Belongs to the peptidase S26 family. RuleBase RU003989

Ontologies

Keywords
Molecular function	Hydrolase Protease RuleBase RU003988
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	serine-type peptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8EK14 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 60B6CB1916571641	FASTA	263	29,607
	10 20 30 40 50 60 MTEPVRLNEK GAQVKPRAEG GIGETVKVVL QALLIALVVR TFLFQPFNIP SGSMIPTLLI 70 80 90 100 110 120 GDYLFVSKYA YGYSRHSIPF SPDLFHGRLF SSPPKRGDVA VFKLPRDGQT DYIKRVIGLP 130 140 150 160 170 180 GDKIQMKDGR LFINDELVPR EPIAKAHTED FYGRETDVPT YEETLPGGVK HTIIEIQGDT 190 200 210 220 230 240 GFNDNTQAFV VPPDHYFMMG DNRDNSTDSR VSPDQGGVGY VPFDNFVGRA ELIFFSVGKG 250 260 APAWAFWEWP WTVRWDRMLK PVH

References

[1]

"Complete sequence of Methylocella silvestris BL2." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Forester B., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Dunfield P.F., Dedysh S.N., Liesack W. , Stott M.B., Smirnova A.V., Alam M., Chen Y., Murrell J.C., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: BL2 / DSM 15510 / NCIMB 13906.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001280 Genomic DNA. Translation: ACK49961.1.
RefSeq	YP_002361323.1. NC_011666.1.
3D structure databases
ProteinModelPortal	B8EK14.
ModBase	Search...
Protein-protein interaction databases
STRING	395965.Msil_0992.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACK49961; ACK49961; Msil_0992.
GeneID	7093671.
KEGG	msl:Msil_0992.
PATRIC	22597417. VBIMetSil55537_1089.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0681.
HOGENOM	HOG000003673.
KO	K03100.
OMA	RIMERTP.
ProtClustDB	CLSK2405732.
Family and domain databases
Gene3D	2.10.109.10. 2 hits.
InterPro	IPR000223. Pept_S26A_signal_pept_1. IPR019758. Pept_S26A_signal_pept_1_CS. IPR019757. Pept_S26A_signal_pept_1_Lys-AS. IPR019756. Pept_S26A_signal_pept_1_Ser-AS. IPR019759. Peptidase_S24_S26. IPR015927. Peptidase_S24_S26A/B/C. IPR011056. Peptidase_S24_S26A/B/C_b-rbn. [Graphical view]
PANTHER	PTHR12383. PTHR12383. 1 hit.
Pfam	PF00717. Peptidase_S24. 1 hit. [Graphical view]
PRINTS	PR00727. LEADERPTASE.
SUPFAM	SSF51306. Pept_S24_S26_C. 1 hit.
TIGRFAMs	TIGR02227. sigpep_I_bact. 1 hit.
PROSITE	PS00501. SPASE_I_1. 1 hit. PS00760. SPASE_I_2. 1 hit. PS00761. SPASE_I_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8EK14_METSB

Accession

Primary (citable) accession number: B8EK14

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)