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B8EJS1 (TRPC_METSB) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Indole-3-glycerol phosphate synthase
Short name=IGPS
EC=4.1.1.48
Gene names
Name:trpC
Ordered Locus Names:Msil_0503
OrganismMethylocella silvestris (strain BL2 / DSM 15510 / NCIMB 13906) [Complete proteome] [HAMAP]
Taxonomic identifier395965 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Beijerinckiaceae › Methylocella

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. HAMAP MF_00134_B

Pathway

Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. HAMAP MF_00134_B

Sequence similarities

Belongs to the TrpC family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Indole-3-glycerol phosphate synthase HAMAP MF_00134_B
PRO_1000198778

Sequences

Sequence LengthMass (Da)Tools
B8EJS1 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 5D51554F6A269D84

FASTA27630,334
        10         20         30         40         50         60 
MTDILKSIAL YKRREIAQAK VRMPFETLER KAHDHDPPRG FVKAIEAKHA VNQLALIAEM 

        70         80         90        100        110        120 
KKASPSKGLI RADFDPPALA RAYEEGGAAC LSVLTDGPSF QGDLSFLEAA RAATHLPCLR 

       130        140        150        160        170        180 
KDFLFDPYQV YEARANGADC VLIIMACVDD EEAGQLTRAA HDLAMDILVE VHDEAELTRA 

       190        200        210        220        230        240 
LRLETRLVGV NNRDLRTFET SLELTERLAE KIPSDRIAVS ESGIASHQDC LRLKAHGVST 

       250        260        270 
FLVGESLMRQ KDVAAATKDL LIGKLPPLHG KHAHGL

« Hide

References

[1]"Complete sequence of Methylocella silvestris BL2."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Forester B., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Dunfield P.F., Dedysh S.N., Liesack W. expand/collapse author list , Stott M.B., Smirnova A.V., Alam M., Chen Y., Murrell J.C., Richardson P.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: BL2 / DSM 15510 / NCIMB 13906.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001280 Genomic DNA. Translation: ACK49475.1.
RefSeqYP_002360837.1. NC_011666.1.

3D structure databases

ProteinModelPortalB8EJS1.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8EJS1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7091236.
GenomeReviewsGene locus Msil_0503 in contig CP001280_GR.
KEGGmsl:Msil_0503.
PATRIC22596313. VBIMetSil55537_0549.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG540956.
OMAMRKDDVT.

Family and domain databases

HAMAPMF_00134_B. IGPS_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR013798. Indole-3-glycerol_P_synth.
IPR001468. Indole-3-GlycerolPSynthase_CS.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01609.
PfamPF00218. IGPS. 1 hit.
[Graphical view]
SUPFAMSSF51366. RibP_bind_barrel. 1 hit.
PROSITEPS00614. IGPS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRPC_METSB
AccessionPrimary (citable) accession number: B8EJS1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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