B8EC84 (B8EC84_SHEB2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Peptide deformylase 3 HAMAP MF_00163
Short name=PDF 3 HAMAP MF_00163
EC=3.5.1.88 HAMAP MF_00163

Alternative name(s):
Polypeptide deformylase 3 HAMAP MF_00163

Gene names

Name:	def3 HAMAP MF_00163
Ordered Locus Names:	Sbal223_3401

Organism

Shewanella baltica (strain OS223) [Complete proteome] [HAMAP]

Taxonomic identifier

407976 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella

Protein attributes

Sequence length	185 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions By similarity. HAMAP MF_00163
Catalytic activity	Formyl-L-methionyl peptide + H2O = formate + methionyl peptide. HAMAP MF_00163 SAAS SAAS000181
Cofactor	Binds 1 Fe2+ ion By similarity. HAMAP MF_00163
Sequence similarities	Belongs to the polypeptide deformylase family. HAMAP MF_00163

Ontologies

Keywords
Biological process	Protein biosynthesis SAAS SAAS000181 HAMAP MF_00163
Ligand	Iron HAMAP MF_00163 Metal-binding HAMAP MF_00163 SAAS SAAS000181
Molecular function	Hydrolase HAMAP MF_00163 SAAS SAAS000181 EMBL ACK47885.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: HAMAP
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro peptide deformylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	152	1	By similarity HAMAP MF_00163
	Metal binding	109	1	Iron By similarity HAMAP MF_00163
	Metal binding	151	1	Iron By similarity HAMAP MF_00163
	Metal binding	155	1	Iron By similarity HAMAP MF_00163

Sequences

	Sequence		Length	Mass (Da)
	B8EC84 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: E948A9CC51202362	FASTA	185	20,295
	10 20 30 40 50 60 MFKHLMPKQT PPLLPIALVG EAILGRTAIA VHHFDAELAH LAEQMSASME AAKGVGIAAP 70 80 90 100 110 120 QVHSPLALFI MASRPNERYP DAPNMAPVVV VNPQIIHASS DLVGGEEGCL SVPGQRFNIL 130 140 150 160 170 180 RHQAIEVRYQ NLQGEWQQAE LTGFIARIFQ HEFDHLQGIT LLERSRMPEQ AQSISAQSIE QGEAQ

References

[1]

"Complete sequence of chromosome of Shewanella baltica OS223." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Meincke L., Brettin T., Detter J.C., Han C., Kuske C.R., Larimer F., Land M., Hauser L. , Kyrpides N., Ovchinnikova G., Brettar I., Rodrigues J., Konstantinidis K., Tiedje J. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: OS223.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001252 Genomic DNA. Translation: ACK47885.1.
RefSeq	YP_002359308.1. NC_011663.1.
3D structure databases
ProteinModelPortal	B8EC84.
ModBase	Search...
Protein-protein interaction databases
STRING	B8EC84.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7086015.
GenomeReviews	Gene locus Sbal223_3401 in contig CP001252_GR.
KEGG	sbp:Sbal223_3401.
PATRIC	23483189. VBISheBal125792_3516.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG665227.
OMA	IRYEGFD.
ProtClustDB	CLSK906069.
Family and domain databases
HAMAP	MF_00163. Pep_deformylase. [Tree]
InterPro	IPR000181. Fmet_deformylase. IPR023635. Peptide_deformylase. [Graphical view]
Gene3D	G3DSA:3.90.45.10. Fmet_deformylase. 1 hit.
KO	K01462.
PANTHER	PTHR10458. Fmet_deformylase. 1 hit.
Pfam	PF01327. Pep_deformylase. 1 hit. [Graphical view]
PIRSF	PIRSF004749. Pep_def. 1 hit.
PRINTS	PR01576. PDEFORMYLASE.
SUPFAM	SSF56420. Fmet_deformylase. 1 hit.
TIGRFAMs	TIGR00079. Pept_deformyl. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8EC84_SHEB2

Accession

Primary (citable) accession number: B8EC84

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)