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B8E2K4 (B8E2K4_DICTD) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dihydroorotase RuleBase RU003441
EC=3.5.2.3 RuleBase RU003441
Gene names
Ordered Locus Names:Dtur_1574
OrganismDictyoglomus turgidum (strain Z-1310 / DSM 6724)
Taxonomic identifier515635 [NCBI]
Taxonomic lineageBacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length431 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-dihydroorotate + H2O = N-carbamoyl-L-aspartate. RuleBase RU003441 SAAS SAAS002195

Cofactor

Binds 2 zinc ions per subunit By similarity. RuleBase RU003441 SAAS SAAS002195

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 3/3. RuleBase RU003441 SAAS SAAS002195

Subunit structure

Homodimer By similarity. SAAS SAAS002195

Sequence similarities

Belongs to the DHOase family. Type 2 subfamily. RuleBase RU003441

Sequences

Sequence LengthMass (Da)Tools
B8E2K4 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 3D9FCDF7C4F16700

FASTA43148,512
        10         20         30         40         50         60 
MKILFKNITL VYPEKDKEEI GDLYIEDRII KRIGKGLDIN GNVEVIDGKD KIVVPTLVDI 

        70         80         90        100        110        120 
HVHLREPGYE WKETIESGSK AAVAGGFTAI CCMPNTNPPI DNKEMVRFIY EKADIVGLSR 

       130        140        150        160        170        180 
VYPIGTITKG REGKEISEMG DMFMAGAKGF SDDGSCVMNS EVLRCALEYS KIFNAPIIEH 

       190        200        210        220        230        240 
AEDTNLTLEG NVNFGKISTL LGFKGMPWVA EASIVARDVF LSALTGGRLH IAHISCWQSL 

       250        260        270        280        290        300 
DMIKWGKEHG ANITCEVTPH HLVLTEDAVK EMNYDTNTKM NPPLRTKEDQ EALWEGIKND 

       310        320        330        340        350        360 
LIDVIATDHA PHHLDDKMVE YGLAEYGISG LETAIPLVIT YGYYERKIPL SKLFKKMSYN 

       370        380        390        400        410        420 
PCKILNLPYI PLEESVPANL TIIDLSEKEV EKEKFFSKGK NTPFHGWRLK GWPVMTFVEG 

       430 
RLVYREGKIL W

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References

[1]"Complete sequence of Dictyoglomus turgidum DSM 6724."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Z-1310 / DSM 6724.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001251 Genomic DNA. Translation: ACK42848.1.
RefSeqYP_002353462.1. NC_011661.1.

3D structure databases

ProteinModelPortalB8E2K4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8E2K4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7082009.
GenomeReviewsGene locus Dtur_1574 in contig CP001251_GR.
KEGGdtu:Dtur_1574.
PATRIC21811950. VBIDicTur93964_1622.

Phylogenomic databases

HOGENOMHBG724623.
OMACDVHPVG.
PhylomeDBB8E2K4.
ProtClustDBCLSK2409859.

Family and domain databases

HAMAPMF_00220_B. PyrC_type2_B.
[Tree]
InterProIPR006680. Amidohydro_1.
IPR004722. DHOase.
IPR002195. Dihydroorotase_CS.
IPR011059. Metal-dep_hydrolase_composite.
[Graphical view]
KOK01465.
PfamPF01979. Amidohydro_1. 1 hit.
[Graphical view]
SUPFAMSSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMsTIGR00857. PyrC_multi. 1 hit.
PROSITEPS00482. DIHYDROOROTASE_1. 1 hit.
PS00483. DIHYDROOROTASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8E2K4_DICTD
AccessionPrimary (citable) accession number: B8E2K4
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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