B8E224 (B8E224_DICTD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Holo-[acyl-carrier-protein] synthase HAMAP MF_00101
Short name=Holo-ACP synthase HAMAP MF_00101
EC=2.7.8.7 HAMAP MF_00101

Alternative name(s):
4'-phosphopantetheinyl transferase AcpS HAMAP MF_00101

Gene names

Name:	acpS HAMAP MF_00101
Ordered Locus Names:	Dtur_1021

Organism

Dictyoglomus turgidum (strain Z-1310 / DSM 6724)

Taxonomic identifier

515635 [NCBI]

Taxonomic lineage

Bacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length	126 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein By similarity. HAMAP MF_00101
Catalytic activity	CoA-(4'-phosphopantetheine) + apo-[acyl-carrier-protein] = adenosine 3',5'-bisphosphate + holo-[acyl-carrier-protein]. HAMAP MF_00101
Cofactor	Magnesium By similarity. HAMAP MF_00101
Subcellular location	Cytoplasm By similarity HAMAP MF_00101.
Sequence similarities	Belongs to the P-Pant transferase superfamily. AcpS family. HAMAP MF_00101

Ontologies

Keywords
Biological process	Fatty acid biosynthesis HAMAP MF_00101 Lipid synthesis
Cellular component	Cytoplasm HAMAP MF_00101
Ligand	Magnesium HAMAP MF_00101 Metal-binding HAMAP MF_00101
Molecular function	Transferase HAMAP MF_00101
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP macromolecule biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	holo-[acyl-carrier-protein] synthase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Metal binding	11	1	Magnesium By similarity HAMAP MF_00101
	Metal binding	59	1	Magnesium By similarity HAMAP MF_00101

Sequences

	Sequence		Length	Mass (Da)
	B8E224 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 71541D4687C6FAAC	FASTA	126	14,521
	10 20 30 40 50 60 MENISLEVGL DIIEIERIKN ACEKHRNFKE RIYSHEELKQ LGNKKDIYAS LAARFAAKEA 70 80 90 100 110 120 FIKALGGKYE GWRWKDIEIL YGLNGKPEIR LKNKALEMAL QKGVKEIKVS LSHTHKYAVA IVILVR

References

[1]

"Complete sequence of Dictyoglomus turgidum DSM 6724." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Z-1310 / DSM 6724.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001251 Genomic DNA. Translation: ACK42301.1.
RefSeq	YP_002352915.1. NC_011661.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B8E224.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7081829.
GenomeReviews	Gene locus Dtur_1021 in contig CP001251_GR.
KEGG	dtu:Dtur_1021.
PATRIC	21810750. VBIDicTur93964_1058.
Phylogenomic databases
HOGENOM	HBG734479.
OMA	NSSAIAY.
PhylomeDB	B8E224.
ProtClustDB	CLSK2409498.
Family and domain databases
HAMAP	MF_00101. AcpS. [Tree]
InterPro	IPR008278. 4-PPantetheinyl_Trfase. IPR002582. ACPS. IPR004568. PPantethiene-prot_Trfase. [Graphical view]
Gene3D	G3DSA:3.90.470.20. G3DSA:3.90.470.20. 1 hit.
KO	K00997.
Pfam	PF01648. ACPS. 1 hit. [Graphical view]
ProDom	PD004282. PPantethiene-prot_Trfase. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF56214. 4-PPT_transf. 1 hit.
TIGRFAMs	TIGR00516. AcpS. 1 hit. TIGR00556. Pantethn_trn. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8E224_DICTD

Accession

Primary (citable) accession number: B8E224

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)