B8E222 (GLMM_DICTD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Dtur_1019

Organism

Dictyoglomus turgidum (strain Z-1310 / DSM 6724)

Taxonomic identifier

515635 [NCBI]

Taxonomic lineage

Bacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length	447 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 447	447	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000201088
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	239	1	Magnesium By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B8E222 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: C1F815E092616CC7	FASTA	447	49,989
	10 20 30 40 50 60 MRRFFGTDGI RGVVNEDLTP ELAYKLSRAI VGYFGNVKGK KVIIGSDTRN SKDMLKSALV 70 80 90 100 110 120 AGFTSGGMNV LDVGVISTPA LSYLVKNQDE VLLGVMISAS HNPVEYNGIK IFKNDGFKLD 130 140 150 160 170 180 DDVEAEIENY LLKEDNYYRA NPREIGVIYD FSHIKEKYKN YLREIINGNF EGYKVMLDCA 190 200 210 220 230 240 FGSLSEIAPE VFRELGAEVV AYNTKYNGLN INENCGAVYP ETSKKLFLNS GAHIGFTYDG 250 260 270 280 290 300 DGDRVIAFSE NGEIIDGDIM LGILAKYLKE KGLLKGDKIV GTIMTNLGLE EYLKNINVEL 310 320 330 340 350 360 IRTKVGDRYV LDEILKYGLN LGGETSGHII LFDYMSTGDG LLTSLFLLKI LKEKGVKLSE 370 380 390 400 410 420 LAKDIKIFPQ VHEKVSVKGL NITEDMEKRF IEITEEVING KNIRYIVRKS GTEPVVRITL 430 440 EGDVPKEYLN ELVLEIKSRI IDLLSNF

References

[1]

"Complete sequence of Dictyoglomus turgidum DSM 6724." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Z-1310 / DSM 6724.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001251 Genomic DNA. Translation: ACK42299.1.
RefSeq	YP_002352913.1. NC_011661.1.
3D structure databases
ProteinModelPortal	B8E222.
ModBase	Search...
Protein-protein interaction databases
STRING	B8E222.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7081827.
GenomeReviews	Gene locus Dtur_1019 in contig CP001251_GR.
KEGG	dtu:Dtur_1019.
PATRIC	21810746. VBIDicTur93964_1056.
Phylogenomic databases
HOGENOM	HBG644964.
OMA	GVGSTHL.
PhylomeDB	B8E222.
ProtClustDB	CLSK2409410.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_DICTD

Accession

Primary (citable) accession number: B8E222

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program