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Protein

Methionyl-tRNA formyltransferase

Gene

fmt

Organism
Dictyoglomus turgidum (strain Z-1310 / DSM 6724)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.UniRule annotation

Catalytic activityi

10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionTransferase
Biological processProtein biosynthesis

Enzyme and pathway databases

BioCyciDTUR515635:G1GU5-1488-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Methionyl-tRNA formyltransferaseUniRule annotation (EC:2.1.2.9UniRule annotation)
Gene namesi
Name:fmtUniRule annotation
Ordered Locus Names:Dtur_1439
OrganismiDictyoglomus turgidum (strain Z-1310 / DSM 6724)
Taxonomic identifieri515635 [NCBI]
Taxonomic lineageiBacteriaDictyoglomiDictyoglomalesDictyoglomaceaeDictyoglomus
Proteomesi
  • UP000007719 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001184751 – 314Methionyl-tRNA formyltransferaseAdd BLAST314

Proteomic databases

PRIDEiB8E0X6

Interactioni

Protein-protein interaction databases

STRINGi515635.Dtur_1439

Structurei

3D structure databases

ProteinModelPortaliB8E0X6
SMRiB8E0X6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni109 – 112Tetrahydrofolate (THF) bindingUniRule annotation4

Sequence similaritiesi

Belongs to the Fmt family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CAE Bacteria
COG0223 LUCA
HOGENOMiHOG000261177
InParanoidiB8E0X6
KOiK00604
OMAiLRIVFMG
OrthoDBiPOG091H01YM

Family and domain databases

Gene3Di3.10.25.10, 1 hit
HAMAPiMF_00182 Formyl_trans, 1 hit
InterProiView protein in InterPro
IPR005794 Fmt
IPR005793 Formyl_trans_C
IPR037022 Formyl_trans_C_sf
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR011034 Formyl_transferase-like_C_sf
PfamiView protein in Pfam
PF02911 Formyl_trans_C, 1 hit
PF00551 Formyl_trans_N, 1 hit
SUPFAMiSSF50486 SSF50486, 1 hit
SSF53328 SSF53328, 1 hit
TIGRFAMsiTIGR00460 fmt, 1 hit

Sequencei

Sequence statusi: Complete.

B8E0X6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRIIYFGTPE FSRIILERIS PYLNIIAVVT QPDKPKGRGK RIMCSPVKDF
60 70 80 90 100
AISKGIPVYQ PEKLKGNKEF FEIIRSLNPE ALVVASYGKI IPEDILNIPP
110 120 130 140 150
YGGINVHASV LPKYRGAAPI ERAIMNCEKE TGVSIMKMER GLDTGPVYAI
160 170 180 190 200
RKIPILPDDN RGTLSIKLAH LGAELLLEVL PLIKDGKLSP VPQEESLATY
210 220 230 240 250
APKLSKEEEI IDWNMRGEKI WCQIRALSPE PGAMTFFRGK ILKIFKADFE
260 270 280 290 300
EKIFNEEIIN GTIIEQNKKR GIGVKVNNGI LWLLELQPEG KKRMSFLEFM
310
NGYRLNIGER FENS
Length:314
Mass (Da):35,509
Last modified:March 3, 2009 - v1
Checksum:i076B0305DF96FD3B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001251 Genomic DNA Translation: ACK42713.1
RefSeqiWP_012583791.1, NC_011661.1
YP_002353327.1, NC_011661.1

Genome annotation databases

EnsemblBacteriaiACK42713; ACK42713; Dtur_1439
GeneIDi7081874
KEGGidtu:Dtur_1439
PATRICifig|515635.4.peg.1486

Similar proteinsi

Entry informationi

Entry nameiFMT_DICTD
AccessioniPrimary (citable) accession number: B8E0X6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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