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Protein

Acetylglutamate kinase

Gene

argB

Organism
Dictyoglomus turgidum (strain Z-1310 / DSM 6724)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate 5-phosphate.UniRule annotationSAAS annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei9 – 91Transition state stabilizerUniRule annotation
Binding sitei63 – 631SubstrateUniRule annotation
Binding sitei156 – 1561SubstrateUniRule annotation
Sitei219 – 2191Transition state stabilizerUniRule annotation

GO - Molecular functioni

  1. acetylglutamate kinase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciDTUR515635:GH4F-1396-MONOMER.
UniPathwayiUPA00068; UER00107.

Names & Taxonomyi

Protein namesi
Recommended name:
Acetylglutamate kinaseUniRule annotation (EC:2.7.2.8UniRule annotation)
Alternative name(s):
N-acetyl-L-glutamate 5-phosphotransferaseUniRule annotation
NAG kinaseUniRule annotation
Gene namesi
Name:argBUniRule annotation
Ordered Locus Names:Dtur_1355Imported
OrganismiDictyoglomus turgidum (strain Z-1310 / DSM 6724)Imported
Taxonomic identifieri515635 [NCBI]
Taxonomic lineageiBacteriaDictyoglomiDictyoglomalesDictyoglomaceaeDictyoglomus
ProteomesiUP000007719: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi515635.Dtur_1355.

Structurei

3D structure databases

ProteinModelPortaliB8E0I4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni41 – 422Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the acetylglutamate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0548.
HOGENOMiHOG000233259.
InParanoidiB8E0I4.
KOiK00930.
OMAiGIESKMV.
OrthoDBiEOG6T1WVF.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
HAMAPiMF_00082_B. ArgB_B.
InterProiIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000728. NAGK. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00761. argB. 1 hit.

Sequencei

Sequence statusi: Complete.

B8E0I4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKNLVLIKI GGNVLNKFSL FLSFIKDLYD KGYDFVFLHG GGNEINYWME
60 70 80 90 100
RFGLEPKFVK GRRVTDENTL KIVEMVLSGE IQGRVISEIK KVGLKVVGLN
110 120 130 140 150
GKSIFNCRKL FIDGIDLGYV GEVVGVEVSA IEKLLEERYI IVTTSLGIDE
160 170 180 190 200
QGNSYNVNAD SAALALGVHL KVERLIFCTD VPGIILKQNG EEVVLNKLSV
210 220 230 240 250
EEAKRLIEIG EVFGGMIPKL ESAIVAIENG VKTVQIWGGL DFSKAWNMEE

GTLIYK
Length:256
Mass (Da):28,391
Last modified:March 3, 2009 - v1
Checksum:i018B5F6F68DE9316
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001251 Genomic DNA. Translation: ACK42629.1.
RefSeqiWP_012583710.1. NC_011661.1.
YP_002353243.1. NC_011661.1.

Genome annotation databases

EnsemblBacteriaiACK42629; ACK42629; Dtur_1355.
GeneIDi7083321.
KEGGidtu:Dtur_1355.
PATRICi21811490. VBIDicTur93964_1400.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001251 Genomic DNA. Translation: ACK42629.1.
RefSeqiWP_012583710.1. NC_011661.1.
YP_002353243.1. NC_011661.1.

3D structure databases

ProteinModelPortaliB8E0I4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi515635.Dtur_1355.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK42629; ACK42629; Dtur_1355.
GeneIDi7083321.
KEGGidtu:Dtur_1355.
PATRICi21811490. VBIDicTur93964_1400.

Phylogenomic databases

eggNOGiCOG0548.
HOGENOMiHOG000233259.
InParanoidiB8E0I4.
KOiK00930.
OMAiGIESKMV.
OrthoDBiEOG6T1WVF.

Enzyme and pathway databases

UniPathwayiUPA00068; UER00107.
BioCyciDTUR515635:GH4F-1396-MONOMER.

Family and domain databases

Gene3Di3.40.1160.10. 1 hit.
HAMAPiMF_00082_B. ArgB_B.
InterProiIPR004662. AcgluKinase.
IPR001048. Asp/Glu/Uridylate_kinase.
[Graphical view]
PfamiPF00696. AA_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF000728. NAGK. 1 hit.
SUPFAMiSSF53633. SSF53633. 1 hit.
TIGRFAMsiTIGR00761. argB. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Dictyoglomus turgidum DSM 6724."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D.
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Z-1310 / DSM 6724Imported.

Entry informationi

Entry nameiB8E0I4_DICTD
AccessioniPrimary (citable) accession number: B8E0I4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: February 4, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.