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B8E0B1

- NADD_DICTD

UniProt

B8E0B1 - NADD_DICTD

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Protein

Probable nicotinate-nucleotide adenylyltransferase

Gene
nadD, Dtur_1278
Organism
Dictyoglomus turgidum (strain Z-1310 / DSM 6724)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) By similarity.UniRule annotation

Catalytic activityi

ATP + beta-nicotinate-D-ribonucleotide = diphosphate + deamido-NAD+.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. nicotinate-nucleotide adenylyltransferase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Keywords - Ligandi

ATP-binding, NAD, Nucleotide-binding

Enzyme and pathway databases

BioCyciDTUR515635:GH4F-1314-MONOMER.
UniPathwayiUPA00253; UER00332.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable nicotinate-nucleotide adenylyltransferase (EC:2.7.7.18)
Alternative name(s):
Deamido-NAD(+) diphosphorylase
Deamido-NAD(+) pyrophosphorylase
Nicotinate mononucleotide adenylyltransferase
Short name:
NaMN adenylyltransferase
Gene namesi
Name:nadD
Ordered Locus Names:Dtur_1278
OrganismiDictyoglomus turgidum (strain Z-1310 / DSM 6724)
Taxonomic identifieri515635 [NCBI]
Taxonomic lineageiBacteriaDictyoglomiDictyoglomalesDictyoglomaceaeDictyoglomus
ProteomesiUP000007719: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 203203Probable nicotinate-nucleotide adenylyltransferaseUniRule annotationPRO_1000192232Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi515635.Dtur_1278.

Family & Domainsi

Sequence similaritiesi

Belongs to the NadD family.

Phylogenomic databases

eggNOGiCOG1057.
HOGENOMiHOG000262780.
KOiK00969.
OMAiILVYPRS.
OrthoDBiEOG6F55KJ.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00244. NaMN_adenylyltr.
InterProiIPR004821. Cyt_trans-like.
IPR005248. NAMN_adtrnsfrase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR12039. PTHR12039. 1 hit.
PfamiPF01467. CTP_transf_2. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00125. cyt_tran_rel. 1 hit.
TIGR00482. TIGR00482. 1 hit.

Sequencei

Sequence statusi: Complete.

B8E0B1-1 [UniParc]FASTAAdd to Basket

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MKIGILGGTF DPIHYGHLWF AEYAREKFKL DKVFFIPNRV PSHREIPIAT    50
SKQRYEMVLL ATLNNPYFEV LPIELEREGV SYMVDTIRDL STYFSNAELY 100
LLLGNDAFRD FLKWKDPYKI VEKVSIIVGS RGEEYYTNDL KDFIKTFENK 150
IFFLDFPYYP ISAKEIRDRV KKGLSIKYLV PENVEEYIIK NSVYCEEDQK 200
DVK 203
Length:203
Mass (Da):24,059
Last modified:March 3, 2009 - v1
Checksum:iE6C417DE1451EDD4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001251 Genomic DNA. Translation: ACK42556.1.
RefSeqiYP_002353170.1. NC_011661.1.

Genome annotation databases

EnsemblBacteriaiACK42556; ACK42556; Dtur_1278.
GeneIDi7082762.
KEGGidtu:Dtur_1278.
PATRICi21811314. VBIDicTur93964_1318.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001251 Genomic DNA. Translation: ACK42556.1 .
RefSeqi YP_002353170.1. NC_011661.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 515635.Dtur_1278.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACK42556 ; ACK42556 ; Dtur_1278 .
GeneIDi 7082762.
KEGGi dtu:Dtur_1278.
PATRICi 21811314. VBIDicTur93964_1318.

Phylogenomic databases

eggNOGi COG1057.
HOGENOMi HOG000262780.
KOi K00969.
OMAi ILVYPRS.
OrthoDBi EOG6F55KJ.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00332 .
BioCyci DTUR515635:GH4F-1314-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
HAMAPi MF_00244. NaMN_adenylyltr.
InterProi IPR004821. Cyt_trans-like.
IPR005248. NAMN_adtrnsfrase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
PANTHERi PTHR12039. PTHR12039. 1 hit.
Pfami PF01467. CTP_transf_2. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00125. cyt_tran_rel. 1 hit.
TIGR00482. TIGR00482. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Dictyoglomus turgidum DSM 6724."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D.
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Z-1310 / DSM 6724.

Entry informationi

Entry nameiNADD_DICTD
AccessioniPrimary (citable) accession number: B8E0B1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: May 14, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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