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B8E0A6 (B8E0A6_DICTD) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate--tRNA ligase HAMAP MF_00022
EC=6.1.1.17 HAMAP MF_00022
Alternative name(s):
Glutamyl-tRNA synthetase HAMAP MF_00022
Gene names
Name:gltX HAMAP MF_00022
Ordered Locus Names:Dtur_1273
OrganismDictyoglomus turgidum (strain Z-1310 / DSM 6724)
Taxonomic identifier515635 [NCBI]
Taxonomic lineageBacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length477 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity. HAMAP MF_00022

Catalytic activity

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). HAMAP MF_00022

Subunit structure

Monomer By similarity. HAMAP MF_00022

Subcellular location

Cytoplasm By similarity HAMAP MF_00022.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP MF_00022 RuleBase RU003489

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif10 – 2011"HIGH" region By similarity HAMAP MF_00022
Motif242 – 2465"KMSKS" region By similarity HAMAP MF_00022

Sites

Binding site2451ATP By similarity HAMAP MF_00022

Sequences

Sequence LengthMass (Da)Tools
B8E0A6 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 085EF9416A1B4033

FASTA47756,106
        10         20         30         40         50         60 
MDSVRVRIAP SPTGYLHVGT AHTALFNWLF ARHNKGTFIL RIEDTDLARS TKEYEENIIE 

        70         80         90        100        110        120 
GLKWLGLYWD EGPYYQTQRL DLYRKYADEL LRKGLAYYCY CTPEELEERR KEALAQKKPP 

       130        140        150        160        170        180 
KYDRKCLYLS DEERARYERE GRKPAIRLLV PEGKTVFNDI IRGEIEFNNE DIGDFVIMKS 

       190        200        210        220        230        240 
DGIPTYNFAV VIDDYTMGIT HVIRGEDHIS NTPKQLFIYQ AFGWSPPEFA HLPLLLGPDR 

       250        260        270        280        290        300 
SKLSKRHGVT SVTEYKNMGY LPQALVNYLA LLGWTPEENK EIYTVEELIE LFDLRRVTKN 

       310        320        330        340        350        360 
PGIFDVTKLE WINTQHIRRL SLEELADLTY PFLKEAEWFK EENFKREYYL KVLTLLQERL 

       370        380        390        400        410        420 
KTLAQIREYA DYFFVDDLDY DVEIAKKVCK HPDTPLYLEK IKEVWSQIQE FTAENLENSL 

       430        440        450        460        470 
RNLAEENQIP TKNLVHPIRV ALTNKTVGPG LYEIAEVLGK DKTLKRLEKF IEFLRSL

« Hide

References

[1]"Complete sequence of Dictyoglomus turgidum DSM 6724."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Z-1310 / DSM 6724.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001251 Genomic DNA. Translation: ACK42551.1.
RefSeqYP_002353165.1. NC_011661.1.

3D structure databases

ProteinModelPortalB8E0A6.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8E0A6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7082757.
GenomeReviewsGene locus Dtur_1273 in contig CP001251_GR.
KEGGdtu:Dtur_1273.
PATRIC21811304. VBIDicTur93964_1313.

Phylogenomic databases

HOGENOMHBG628189.
OMAANFNDES.
PhylomeDBB8E0A6.
ProtClustDBPRK01406.

Family and domain databases

HAMAPMF_00022_B. Glu_tRNA_synth_B.
[Tree]
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-synth_Ib_bac/mito.
IPR000924. Glu/Gln-tRNA-synth_Ib.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
Gene3DG3DSA:1.10.1160.10. Glu/Gln-tRNA-synth_Ic_a-bdl. 1 hit.
G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 2 hits.
G3DSA:1.10.10.350. tRNA_synt_bd. 1 hit.
KOK09698.
PANTHERPTHR10119. Glu_tRNA-synt_1c. 1 hit.
PTHR10119:SF1. PTHR10119:SF1. 1 hit.
PfamPF00749. tRNA-synt_1c. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF48163. tRNA-synt_bind. 1 hit.
TIGRFAMsTIGR00464. GltX_bact. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8E0A6_DICTD
AccessionPrimary (citable) accession number: B8E0A6
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info