B8E021 (B8E021_DICTD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Lipid-A-disaccharide synthase EMBL ACK42104.1
EC=2.4.1.182 EMBL ACK42104.1

Gene names

Ordered Locus Names:

Dtur_0823

Organism

Dictyoglomus turgidum (strain Z-1310 / DSM 6724)

Taxonomic identifier

515635 [NCBI]

Taxonomic lineage

Bacteria › Dictyoglomi › Dictyoglomales › Dictyoglomaceae › Dictyoglomus

Protein attributes

Sequence length	363 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell By similarity. SAAS SAAS003835
Catalytic activity	UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate = UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. SAAS SAAS003835
Pathway	Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6. SAAS SAAS003835

Ontologies

Keywords
Biological process	Lipid A biosynthesis SAAS SAAS003835 Lipid synthesis
Molecular function	Glycosyltransferase SAAS SAAS003835 EMBL ACK42104.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	lipid A biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	lipid-A-disaccharide synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8E021 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 9CD35C5A9A548D10	FASTA	363	42,151
	10 20 30 40 50 60 MKIFLSVLEV SADVHGSKLI NALKNKKKDI YFYGLGGERM KEEGMEVMYD VTQYSTVGFI 70 80 90 100 110 120 EPIPYIPKLL LVQEKVKKII KETKPDLIIF IDAQGFNLPL AKYAKKLGIQ TIYYFAPQYW 130 140 150 160 170 180 LWGNQEKARE VLDTVSYVVA TFPQEYNLYK KFGDNVVYFG HPLVDYLLPY ENLEKENDLI 190 200 210 220 230 240 GLFPGSRIQE IKNLVPLFLE ISDRLKEEGY RFVMPIASEK FSEMIFRYIR GKNHIELVSG 250 260 270 280 290 300 RESQKYLKLS SLSLVASGTV TLEAAILKTP VMVFYKISSI TYNIAKRLVH YSFIALPNII 310 320 330 340 350 360 LNQMIYPEFV QKIDIKEVMD SINRILKDED YKINLENKLR ELEFKLGEPG VLERISKFIL EII

References

[1]

"Complete sequence of Dictyoglomus turgidum DSM 6724." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Z-1310 / DSM 6724.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001251 Genomic DNA. Translation: ACK42104.1.
RefSeq	YP_002352718.1. NC_011661.1.
3D structure databases
ProteinModelPortal	B8E021.
ModBase	Search...
Protein-protein interaction databases
STRING	B8E021.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7082775.
GenomeReviews	Gene locus Dtur_0823 in contig CP001251_GR.
KEGG	dtu:Dtur_0823.
PATRIC	21810342. VBIDicTur93964_0862.
Phylogenomic databases
HOGENOM	HBG584837.
OMA	PDFNLGL.
PhylomeDB	B8E021.
ProtClustDB	CLSK2409339.
Family and domain databases
InterPro	IPR003835. Glyco_trans_19. [Graphical view]
KO	K00748.
Pfam	PF02684. LpxB. 1 hit. [Graphical view]
TIGRFAMs	TIGR00215. LpxB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8E021_DICTD

Accession

Primary (citable) accession number: B8E021

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)