SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B8DZX8

- DNLI_DICTD

UniProt

B8DZX8 - DNLI_DICTD

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Probable DNA ligase
Gene
lig, Dtur_0780
Organism
Dictyoglomus turgidum (strain Z-1310 / DSM 6724)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity.UniRule annotation

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

Cofactori

Divalent metal cations By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei243 – 2431ATP By similarity
Active sitei245 – 2451N6-AMP-lysine intermediate By similarity
Binding sitei250 – 2501ATP By similarity
Binding sitei265 – 2651ATP By similarity
Binding sitei295 – 2951ATP By similarity
Binding sitei335 – 3351ATP By similarity
Binding sitei410 – 4101ATP By similarity
Binding sitei416 – 4161ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-HAMAP
  4. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-HAMAP
  3. DNA replication Source: UniProtKB-HAMAP
  4. cell cycle Source: UniProtKB-KW
  5. cell division Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication

Keywords - Ligandi

ATP-binding, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciDTUR515635:GH4F-781-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable DNA ligase (EC:6.5.1.1)
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]
Gene namesi
Name:lig
Ordered Locus Names:Dtur_0780
OrganismiDictyoglomus turgidum (strain Z-1310 / DSM 6724)
Taxonomic identifieri515635 [NCBI]
Taxonomic lineageiBacteriaDictyoglomiDictyoglomalesDictyoglomaceaeDictyoglomus
ProteomesiUP000007719: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 582582Probable DNA ligaseUniRule annotation
PRO_1000189919Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi515635.Dtur_0780.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1793.
HOGENOMiHOG000036008.
KOiK10747.
OMAiGEFYPFQ.
OrthoDBiEOG6Q8HXT.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPiMF_00407. DNA_ligase.
InterProiIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8DZX8-1 [UniParc]FASTAAdd to Basket

« Hide

MLFGELAQYF EKIEKTTKRN EMMEILADLF KRVDKEEIEK IIYLLNGRVA    50
PDYEKIEFGM SEKLVLRAMA LALKVPIFDL EKVYKEVGDL GELIIKYSQN 100
EGKDLTVVET FNTLFEIANL SGEGSVDAKV NRLAFLINSL TPQGGKYLVR 150
IVLGKLRLGV GEPTVMDALS FAKVKDKSLR PFIERAFNIT SDLGYVAKVF 200
WEGGIEALKK IKVEVGKPIR MALAERVSKV EEIVKRLGKC AIEPKFDGFR 250
CQIHKKENNV RIFSRNLEDN THMFPDLVEA VLKQFSDKNV IIEGEAISYN 300
PETGEFYPFQ VTVQRKRKYN ISEMVELYPL QLFAFDILYL NGEDITSLPY 350
IRRRQKLEEA ISEGEKIFVT KNIITNDPKE IQAFFEECIT EGLEGIVAKR 400
LDAPYQAGIR NFNWIKLKRS YQGHLADTVD CVILGYFKGR GHRAKFGIGA 450
LLVGVYDDER DLFKTVAKIG TGPTEEEWVR FREVLDEIKL ESKPNNVESL 500
IEPDVWVEPK YVVVIQADEI TRSPVHTCGR ELDGLGYALR FPRVIGFVRE 550
DKGPYDATTV KEILEMFRGQ KKEKVEEDSD NL 582
Length:582
Mass (Da):66,609
Last modified:March 3, 2009 - v1
Checksum:i8F52513B1C69AED3
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001251 Genomic DNA. Translation: ACK42061.1.
RefSeqiWP_012583146.1. NC_011661.1.
YP_002352675.1. NC_011661.1.

Genome annotation databases

EnsemblBacteriaiACK42061; ACK42061; Dtur_0780.
GeneIDi7082068.
KEGGidtu:Dtur_0780.
PATRICi21810246. VBIDicTur93964_0818.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001251 Genomic DNA. Translation: ACK42061.1 .
RefSeqi WP_012583146.1. NC_011661.1.
YP_002352675.1. NC_011661.1.

3D structure databases

ModBasei Search...

Protein-protein interaction databases

STRINGi 515635.Dtur_0780.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACK42061 ; ACK42061 ; Dtur_0780 .
GeneIDi 7082068.
KEGGi dtu:Dtur_0780.
PATRICi 21810246. VBIDicTur93964_0818.

Phylogenomic databases

eggNOGi COG1793.
HOGENOMi HOG000036008.
KOi K10747.
OMAi GEFYPFQ.
OrthoDBi EOG6Q8HXT.

Enzyme and pathway databases

BioCyci DTUR515635:GH4F-781-MONOMER.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPi MF_00407. DNA_ligase.
InterProi IPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Dictyoglomus turgidum DSM 6724."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D.
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Z-1310 / DSM 6724.

Entry informationi

Entry nameiDNLI_DICTD
AccessioniPrimary (citable) accession number: B8DZX8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: September 3, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi