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B8DZX8 (DNLI_DICTD) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable DNA ligase

EC=6.5.1.1
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP]
Gene names
Name:lig
Ordered Locus Names:Dtur_0780
OrganismDictyoglomus turgidum (strain Z-1310 / DSM 6724) [Reference proteome] [HAMAP]
Taxonomic identifier515635 [NCBI]
Taxonomic lineageBacteriaDictyoglomiDictyoglomalesDictyoglomaceaeDictyoglomus

Protein attributes

Sequence length582 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 582582Probable DNA ligase HAMAP-Rule MF_00407
PRO_1000189919

Sites

Active site2451N6-AMP-lysine intermediate By similarity
Binding site2431ATP By similarity
Binding site2501ATP By similarity
Binding site2651ATP By similarity
Binding site2951ATP By similarity
Binding site3351ATP By similarity
Binding site4101ATP By similarity
Binding site4161ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
B8DZX8 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 8F52513B1C69AED3

FASTA58266,609
        10         20         30         40         50         60 
MLFGELAQYF EKIEKTTKRN EMMEILADLF KRVDKEEIEK IIYLLNGRVA PDYEKIEFGM 

        70         80         90        100        110        120 
SEKLVLRAMA LALKVPIFDL EKVYKEVGDL GELIIKYSQN EGKDLTVVET FNTLFEIANL 

       130        140        150        160        170        180 
SGEGSVDAKV NRLAFLINSL TPQGGKYLVR IVLGKLRLGV GEPTVMDALS FAKVKDKSLR 

       190        200        210        220        230        240 
PFIERAFNIT SDLGYVAKVF WEGGIEALKK IKVEVGKPIR MALAERVSKV EEIVKRLGKC 

       250        260        270        280        290        300 
AIEPKFDGFR CQIHKKENNV RIFSRNLEDN THMFPDLVEA VLKQFSDKNV IIEGEAISYN 

       310        320        330        340        350        360 
PETGEFYPFQ VTVQRKRKYN ISEMVELYPL QLFAFDILYL NGEDITSLPY IRRRQKLEEA 

       370        380        390        400        410        420 
ISEGEKIFVT KNIITNDPKE IQAFFEECIT EGLEGIVAKR LDAPYQAGIR NFNWIKLKRS 

       430        440        450        460        470        480 
YQGHLADTVD CVILGYFKGR GHRAKFGIGA LLVGVYDDER DLFKTVAKIG TGPTEEEWVR 

       490        500        510        520        530        540 
FREVLDEIKL ESKPNNVESL IEPDVWVEPK YVVVIQADEI TRSPVHTCGR ELDGLGYALR 

       550        560        570        580 
FPRVIGFVRE DKGPYDATTV KEILEMFRGQ KKEKVEEDSD NL 

« Hide

References

[1]"Complete sequence of Dictyoglomus turgidum DSM 6724."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Z-1310 / DSM 6724.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001251 Genomic DNA. Translation: ACK42061.1.
RefSeqYP_002352675.1. NC_011661.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING515635.Dtur_0780.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACK42061; ACK42061; Dtur_0780.
GeneID7082068.
KEGGdtu:Dtur_0780.
PATRIC21810246. VBIDicTur93964_0818.

Phylogenomic databases

eggNOGCOG1793.
HOGENOMHOG000036008.
KOK10747.
OMAGEFYPFQ.
OrthoDBEOG6Q8HXT.

Enzyme and pathway databases

BioCycDTUR515635:GH4F-781-MONOMER.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDNLI_DICTD
AccessionPrimary (citable) accession number: B8DZX8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: May 14, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families