B8DYK8 (DCD_DICTD) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	Dtur_0052

Organism

Dictyoglomus turgidum (strain Z-1310 / DSM 6724) [Reference proteome] [HAMAP]

Taxonomic identifier

515635 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Dictyoglomi › Dictyoglomia › Dictyoglomales › Dictyoglomaceae › Dictyoglomus › Dictyoglomus turgidum

Protein attributes

Sequence length	194 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 194	194	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000189827

Sequences

	Sequence		Length	Mass (Da)
	B8DYK8 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 9B7774AC81B38591	FASTA	194	21,824
	10 20 30 40 50 60 MILSDKDIKK YLEERKLVIH PIDDPQKQIQ PSSVDLRLGN SFLHFKVEGR AYIDPTKDNP 70 80 90 100 110 120 QDLMEIIEIE EGKPFFLRPG EFVLGTTIET VKLPDDLVAR VDGRSSLGRL GIIVHATAGY 130 140 150 160 170 180 VDPGFCGQIT LELSNINRVP VALYPGMRIC QISFYKLTSP AETPYYKKAG SKYHNQKGPT 190 ASKLNIDFCV KEDK

References

[1]

"Complete sequence of Dictyoglomus turgidum DSM 6724." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Mead D. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Z-1310 / DSM 6724.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001251 Genomic DNA. Translation: ACK41390.1.
RefSeq	YP_002352004.1. NC_011661.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	515635.Dtur_0052.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACK41390; ACK41390; Dtur_0052.
GeneID	7082319.
KEGG	dtu:Dtur_0052.
PATRIC	21808714. VBIDicTur93964_0053.
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	DTUR515635:GH4F-52-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_DICTD

Accession

Primary (citable) accession number: B8DYK8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program