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Protein

Xylose isomerase

Gene

xylA

Organism
Bifidobacterium animalis subsp. lactis (strain AD011)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei103UniRule annotation1
Active sitei106UniRule annotation1
Metal bindingi234Magnesium 1UniRule annotation1
Metal bindingi270Magnesium 1UniRule annotation1
Metal bindingi270Magnesium 2UniRule annotation1
Metal bindingi273Magnesium 2UniRule annotation1
Metal bindingi298Magnesium 1UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi311Magnesium 2UniRule annotation1
Metal bindingi342Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationImported

Keywords - Biological processi

Carbohydrate metabolism, Pentose shuntUniRule annotationSAAS annotation, Xylose metabolismUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotationImported
Ordered Locus Names:BLA_0485Imported
OrganismiBifidobacterium animalis subsp. lactis (strain AD011)Imported
Taxonomic identifieri442563 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000002456 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliB8DWD3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000252293.
KOiK01805.
OMAiHTFQHEL.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8DWD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGLWDIDKI EYVGRTKGLQ EGLGFQYYDA DKVVAGKKMK DWLRFGVAWW
60 70 80 90 100
HTFDAPLTDP FGDGTAQRPW DGKYSDPMDN ALAKVDYAFE FFTKLGAEYF
110 120 130 140 150
CFHDRDIAPE GDTLRETNAN LDRVVDKIEE NMQSTGVKLL WNTSSLFTNP
160 170 180 190 200
RFVAGASTSP FADVYAYAAA QLKHSLEIGK RLGAENYVFW GGREGYENLW
210 220 230 240 250
VTDMKREQEH MAKFFHMCAD YAKQIGMDAQ FLIEPKAKEP TTHQYDFDAA
260 270 280 290 300
TACNFLRAYD LIDVFKLNLE GNHANLAGHT YQHEIRVARD NGVLGSLDAN
310 320 330 340 350
QGDMLLGWDL DEFPTNLYET TSVMWEVLDE GQIGPHGGLN FDAKPRRTSF
360 370 380 390 400
SAEDLFRAHI AGMDSFAAGL LVADKMHQDK YIEDLVANRY GSYDSGIGKS
410 420 430 440 450
IDDGTATLES LNDYAIDMPQ SEIIASTHPD HLEDVKATIN NYIIDALANA
Length:450
Mass (Da):50,562
Last modified:March 3, 2009 - v1
Checksum:i12AA2B7016389BA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001213 Genomic DNA. Translation: ACL28784.1.
RefSeqiWP_004219358.1. NC_011835.1.

Genome annotation databases

EnsemblBacteriaiACL28784; ACL28784; BLA_0485.
GeneIDi7263895.
KEGGibla:BLA_0485.
PATRICi21103847. VBIBifAni98964_0515.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001213 Genomic DNA. Translation: ACL28784.1.
RefSeqiWP_004219358.1. NC_011835.1.

3D structure databases

ProteinModelPortaliB8DWD3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL28784; ACL28784; BLA_0485.
GeneIDi7263895.
KEGGibla:BLA_0485.
PATRICi21103847. VBIBifAni98964_0515.

Phylogenomic databases

HOGENOMiHOG000252293.
KOiK01805.
OMAiHTFQHEL.

Family and domain databases

Gene3Di3.20.20.150. 1 hit.
HAMAPiMF_00455. Xylose_isom_A. 1 hit.
InterProiIPR013022. Xyl_isomerase-like_TIM-brl.
IPR013452. Xylose_isom_bac.
IPR001998. Xylose_isomerase.
[Graphical view]
PRINTSiPR00688. XYLOSISMRASE.
SUPFAMiSSF51658. SSF51658. 1 hit.
TIGRFAMsiTIGR02630. xylose_isom_A. 1 hit.
PROSITEiPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB8DWD3_BIFA0
AccessioniPrimary (citable) accession number: B8DWD3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 30, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.