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Protein

Xylose isomerase

Gene

xylA

Organism
Bifidobacterium animalis subsp. lactis (strain AD011)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-xylopyranose = D-xylulose.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 2 magnesium ions per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei103UniRule annotation1
Active sitei106UniRule annotation1
Metal bindingi234Magnesium 1UniRule annotation1
Metal bindingi270Magnesium 1UniRule annotation1
Metal bindingi270Magnesium 2UniRule annotation1
Metal bindingi273Magnesium 2UniRule annotation1
Metal bindingi298Magnesium 1UniRule annotation1
Metal bindingi309Magnesium 2UniRule annotation1
Metal bindingi311Magnesium 2UniRule annotation1
Metal bindingi342Magnesium 1UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processCarbohydrate metabolism, Xylose metabolismUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBANI442563:G1GTZ-537-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Xylose isomeraseUniRule annotationSAAS annotation (EC:5.3.1.5UniRule annotationSAAS annotation)
Gene namesi
Name:xylAUniRule annotationImported
Ordered Locus Names:BLA_0485Imported
OrganismiBifidobacterium animalis subsp. lactis (strain AD011)Imported
Taxonomic identifieri442563 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaBifidobacterialesBifidobacteriaceaeBifidobacterium
Proteomesi
  • UP000002456 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliB8DWD3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the xylose isomerase family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000252293
KOiK01805
OMAiHTFQHEL

Family and domain databases

HAMAPiMF_00455 Xylose_isom_A, 1 hit
InterProiView protein in InterPro
IPR036237 Xyl_isomerase-like_sf
IPR013452 Xylose_isom_bac
IPR001998 Xylose_isomerase
PANTHERiPTHR32176:SF0 PTHR32176:SF0, 1 hit
PRINTSiPR00688 XYLOSISMRASE
SUPFAMiSSF51658 SSF51658, 1 hit
TIGRFAMsiTIGR02630 xylose_isom_A, 1 hit
PROSITEiView protein in PROSITE
PS51415 XYLOSE_ISOMERASE, 1 hit

Sequencei

Sequence statusi: Complete.

B8DWD3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGLWDIDKI EYVGRTKGLQ EGLGFQYYDA DKVVAGKKMK DWLRFGVAWW
60 70 80 90 100
HTFDAPLTDP FGDGTAQRPW DGKYSDPMDN ALAKVDYAFE FFTKLGAEYF
110 120 130 140 150
CFHDRDIAPE GDTLRETNAN LDRVVDKIEE NMQSTGVKLL WNTSSLFTNP
160 170 180 190 200
RFVAGASTSP FADVYAYAAA QLKHSLEIGK RLGAENYVFW GGREGYENLW
210 220 230 240 250
VTDMKREQEH MAKFFHMCAD YAKQIGMDAQ FLIEPKAKEP TTHQYDFDAA
260 270 280 290 300
TACNFLRAYD LIDVFKLNLE GNHANLAGHT YQHEIRVARD NGVLGSLDAN
310 320 330 340 350
QGDMLLGWDL DEFPTNLYET TSVMWEVLDE GQIGPHGGLN FDAKPRRTSF
360 370 380 390 400
SAEDLFRAHI AGMDSFAAGL LVADKMHQDK YIEDLVANRY GSYDSGIGKS
410 420 430 440 450
IDDGTATLES LNDYAIDMPQ SEIIASTHPD HLEDVKATIN NYIIDALANA
Length:450
Mass (Da):50,562
Last modified:March 3, 2009 - v1
Checksum:i12AA2B7016389BA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001213 Genomic DNA Translation: ACL28784.1
RefSeqiWP_004219358.1, NC_011835.1

Genome annotation databases

EnsemblBacteriaiACL28784; ACL28784; BLA_0485
GeneIDi29695255
KEGGibla:BLA_0485
PATRICifig|442563.4.peg.515

Similar proteinsi

Entry informationi

Entry nameiB8DWD3_BIFA0
AccessioniPrimary (citable) accession number: B8DWD3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health