B8DUY2 (DCD_BIFA0) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Deoxycytidine triphosphate deaminase
Short name=dCTP deaminase
EC=3.5.4.13

Gene names

Name:	dcd
Ordered Locus Names:	BLA_1529

Organism

Bifidobacterium animalis subsp. lactis (strain AD011) [Complete proteome] [HAMAP]

Taxonomic identifier

442563 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Bifidobacteriales › Bifidobacteriaceae › Bifidobacterium › Bifidobacterium animalis › Bifidobacterium animalis subsp. lactis

Protein attributes

Sequence length	193 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146
Pathway	Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146
Sequence similarities	Belongs to the dCTP deaminase family.

Ontologies

Keywords
Biological process	Nucleotide metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	dUMP biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway dUTP biosynthetic process Inferred from electronic annotation. Source: InterPro pyrimidine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	dCTP deaminase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 193	193	Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146		PRO_1000123137

Sequences

	Sequence		Length	Mass (Da)
	B8DUY2 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: F704B96D3E2359AA	FASTA	193	21,687
	10 20 30 40 50 60 MLLSDRDIRA AHAEGHISLD PWTDEMVQPA SIDVRLDRFF RLFNNHAYTY VDPAENQGEL 70 80 90 100 110 120 TEQFEVGPDE PWILHPGEFA LGSTWEYVKI DETLAARLEG KSSLGRLGIL THSTAGFIDP 130 140 150 160 170 180 GFEGHITLEL SNVSTLPVKL WPGMKIGQMC FFQLSSPSEH PYGSETTGSH YQGQRGPTPS 190 RSYQNFYRAQ ITD

References

[1]

"Genome sequence of the probiotic bacterium Bifidobacterium animalis subsp. lactis AD011." Kim J.F., Jeong H., Yu D.S., Choi S.-H., Hur C.-G., Park M.-S., Yoon S.H., Kim D.-W., Ji G.E., Park H.-S., Oh T.K. J. Bacteriol. 191:678-679(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: AD011.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001213 Genomic DNA. Translation: ACL29811.1.
RefSeq	YP_002470387.1. NC_011835.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	442563.BLA_1529.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACL29811; ACL29811; BLA_1529.
GeneID	7264933.
KEGG	bla:BLA_1529.
PATRIC	21106096. VBIBifAni98964_1604.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0717.
HOGENOM	HOG000228601.
KO	K01494.
OMA	RQDAKYK.
ProtClustDB	PRK00416.
Enzyme and pathway databases
BioCyc	BANI442563:GHG0-1521-MONOMER.
UniPathway	UPA00610; UER00665.
Family and domain databases
HAMAP	MF_00146. dCTP_deaminase.
InterPro	IPR011962. dCTP_deam. IPR008180. dUTP_pyroPase. [Graphical view]
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02274. dCTP_deam. 1 hit.
ProtoNet	Search...

Entry information

Entry name

DCD_BIFA0

Accession

Primary (citable) accession number: B8DUY2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program