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B8DTV7

- EFTU_BIFA0

UniProt

B8DTV7 - EFTU_BIFA0

Protein

Elongation factor Tu

Gene

tuf

Organism
Bifidobacterium animalis subsp. lactis (strain AD011)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi83 – 875GTPUniRule annotation
    Nucleotide bindingi138 – 1414GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciBANI442563:GHG0-1141-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:BLA_1148
    OrganismiBifidobacterium animalis subsp. lactis (strain AD011)
    Taxonomic identifieri442563 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
    ProteomesiUP000002456: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 399399Elongation factor TuPRO_1000201387Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi442563.BLA_1148.

    Structurei

    3D structure databases

    ProteinModelPortaliB8DTV7.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 209200tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni19 – 268G1By similarity
    Regioni62 – 665G2By similarity
    Regioni83 – 864G3By similarity
    Regioni138 – 1414G4By similarity
    Regioni175 – 1773G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGDHATFG.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8DTV7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEKYERTK PHVNIGTIGH VDHGKTTLTA AISKVLHDEY PDLNPEYDFN    50
    QIDAAPEEQQ RGITINIAHI EYQTAKRHYA HVDCPGHADF VKNMITGAAQ 100
    MDGAILVVAA TDGPMAQTRE HVLLAPQVGV PKILVALNKC DMVDDEELIE 150
    LVEEEVRDLL DENGFDRDCP VVHTSAYGAL HDDAPDHDKW VATIKELMDD 200
    VDEYIPTPVH DLDKPFLMPI EDVFTISGRG TVVTGRVERG KLPINTNVEI 250
    VGIRPTQTTT FTSIETFHKQ MDECEAGDNT GLLLRGINRT DVERGQVVAA 300
    PGSVTPHTKF EGEVYVLTKD EGGRHSPFFS NYRPQFYFRT TDVTGVITLP 350
    EGVEMVQPGD HATFTVELIQ PIAMEEGLTF AVREGGHTVG SGRVTKILA 399
    Length:399
    Mass (Da):44,070
    Last modified:March 3, 2009 - v1
    Checksum:i57F7BA8552E1B085
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001213 Genomic DNA. Translation: ACL29436.1.
    RefSeqiWP_012619946.1. NC_011835.1.
    YP_002470012.1. NC_011835.1.

    Genome annotation databases

    EnsemblBacteriaiACL29436; ACL29436; BLA_1148.
    GeneIDi7264553.
    KEGGibla:BLA_1148.
    PATRICi21105269. VBIBifAni98964_1205.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001213 Genomic DNA. Translation: ACL29436.1 .
    RefSeqi WP_012619946.1. NC_011835.1.
    YP_002470012.1. NC_011835.1.

    3D structure databases

    ProteinModelPortali B8DTV7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 442563.BLA_1148.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL29436 ; ACL29436 ; BLA_1148 .
    GeneIDi 7264553.
    KEGGi bla:BLA_1148.
    PATRICi 21105269. VBIBifAni98964_1205.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GDHATFG.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci BANI442563:GHG0-1141-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the probiotic bacterium Bifidobacterium animalis subsp. lactis AD011."
      Kim J.F., Jeong H., Yu D.S., Choi S.-H., Hur C.-G., Park M.-S., Yoon S.H., Kim D.-W., Ji G.E., Park H.-S., Oh T.K.
      J. Bacteriol. 191:678-679(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AD011.

    Entry informationi

    Entry nameiEFTU_BIFA0
    AccessioniPrimary (citable) accession number: B8DTV7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3