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B8DTV7 (EFTU_BIFA0) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu

Short name=EF-Tu
Gene names
Name:tuf
Ordered Locus Names:BLA_1148
OrganismBifidobacterium animalis subsp. lactis (strain AD011) [Complete proteome] [HAMAP]
Taxonomic identifier442563 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Elongation factor Tu HAMAP-Rule MF_00118
PRO_1000201387

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding83 – 875GTP By similarity
Nucleotide binding138 – 1414GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
B8DTV7 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 57F7BA8552E1B085

FASTA39944,070
        10         20         30         40         50         60 
MAKEKYERTK PHVNIGTIGH VDHGKTTLTA AISKVLHDEY PDLNPEYDFN QIDAAPEEQQ 

        70         80         90        100        110        120 
RGITINIAHI EYQTAKRHYA HVDCPGHADF VKNMITGAAQ MDGAILVVAA TDGPMAQTRE 

       130        140        150        160        170        180 
HVLLAPQVGV PKILVALNKC DMVDDEELIE LVEEEVRDLL DENGFDRDCP VVHTSAYGAL 

       190        200        210        220        230        240 
HDDAPDHDKW VATIKELMDD VDEYIPTPVH DLDKPFLMPI EDVFTISGRG TVVTGRVERG 

       250        260        270        280        290        300 
KLPINTNVEI VGIRPTQTTT FTSIETFHKQ MDECEAGDNT GLLLRGINRT DVERGQVVAA 

       310        320        330        340        350        360 
PGSVTPHTKF EGEVYVLTKD EGGRHSPFFS NYRPQFYFRT TDVTGVITLP EGVEMVQPGD 

       370        380        390 
HATFTVELIQ PIAMEEGLTF AVREGGHTVG SGRVTKILA 

« Hide

References

[1]"Genome sequence of the probiotic bacterium Bifidobacterium animalis subsp. lactis AD011."
Kim J.F., Jeong H., Yu D.S., Choi S.-H., Hur C.-G., Park M.-S., Yoon S.H., Kim D.-W., Ji G.E., Park H.-S., Oh T.K.
J. Bacteriol. 191:678-679(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: AD011.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001213 Genomic DNA. Translation: ACL29436.1.
RefSeqYP_002470012.1. NC_011835.1.

3D structure databases

ProteinModelPortalB8DTV7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING442563.BLA_1148.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL29436; ACL29436; BLA_1148.
GeneID7264553.
KEGGbla:BLA_1148.
PATRIC21105269. VBIBifAni98964_1205.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMAVTPHTEF.
OrthoDBEOG6R5C6X.
ProtClustDBPRK00049.

Enzyme and pathway databases

BioCycBANI442563:GHG0-1141-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_BIFA0
AccessionPrimary (citable) accession number: B8DTV7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: April 16, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families