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B8DSW4

- HIS7_BIFA0

UniProt

B8DSW4 - HIS7_BIFA0

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Protein
Imidazoleglycerol-phosphate dehydratase
Gene
hisB, BLA_0801
Organism
Bifidobacterium animalis subsp. lactis (strain AD011)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. imidazoleglycerol-phosphate dehydratase activity Source: UniProtKB-EC

GO - Biological processi

  1. histidine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Amino-acid biosynthesis, Histidine biosynthesis

Enzyme and pathway databases

BioCyciBANI442563:GHG0-796-MONOMER.
UniPathwayiUPA00031; UER00011.

Names & Taxonomyi

Protein namesi
Recommended name:
Imidazoleglycerol-phosphate dehydratase (EC:4.2.1.19)
Short name:
IGPD
Gene namesi
Name:hisB
Ordered Locus Names:BLA_0801
OrganismiBifidobacterium animalis subsp. lactis (strain AD011)
Taxonomic identifieri442563 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeBifidobacterialesBifidobacteriaceaeBifidobacterium
ProteomesiUP000002456: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 200200Imidazoleglycerol-phosphate dehydrataseUniRule annotation
PRO_1000118216Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi442563.BLA_0801.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0131.
HOGENOMiHOG000228064.
KOiK01693.
OMAiEDTAIVM.
OrthoDBiEOG60PHGP.

Family and domain databases

HAMAPiMF_00076. HisB.
InterProiIPR000807. ImidazoleglycerolP_deHydtase.
IPR020565. ImidazoleglycerP_deHydtase_CS.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view]
PANTHERiPTHR23133:SF2. PTHR23133:SF2. 1 hit.
PfamiPF00475. IGPD. 1 hit.
[Graphical view]
SUPFAMiSSF54211. SSF54211. 2 hits.
PROSITEiPS00954. IGP_DEHYDRATASE_1. 1 hit.
PS00955. IGP_DEHYDRATASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8DSW4-1 [UniParc]FASTAAdd to Basket

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MARTAHIVRQ TSESSIDLEL NLDGTGKTNI ETTVPFYNHM MTALGKHSLI    50
DLNIVASGDT DIDAHHTVED TAIVFGEALR QALGDKRGIR RFADATVPLD 100
EALAKAVVDV SGRPYCVCSG EPEGFQYAMI GGHFTGSLVR HVMESIAFHA 150
QICLHMHLIA GRDPHHIAEA EFKALARALR FAIEPDPRIQ GLIPSTKGAL 200
Length:200
Mass (Da):21,718
Last modified:March 3, 2009 - v1
Checksum:iD70EC2D70B1E4052
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001213 Genomic DNA. Translation: ACL29093.1.
RefSeqiYP_002469669.1. NC_011835.1.

Genome annotation databases

EnsemblBacteriaiACL29093; ACL29093; BLA_0801.
GeneIDi7264208.
KEGGibla:BLA_0801.
PATRICi21104505. VBIBifAni98964_0834.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001213 Genomic DNA. Translation: ACL29093.1 .
RefSeqi YP_002469669.1. NC_011835.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 442563.BLA_0801.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL29093 ; ACL29093 ; BLA_0801 .
GeneIDi 7264208.
KEGGi bla:BLA_0801.
PATRICi 21104505. VBIBifAni98964_0834.

Phylogenomic databases

eggNOGi COG0131.
HOGENOMi HOG000228064.
KOi K01693.
OMAi EDTAIVM.
OrthoDBi EOG60PHGP.

Enzyme and pathway databases

UniPathwayi UPA00031 ; UER00011 .
BioCyci BANI442563:GHG0-796-MONOMER.

Family and domain databases

HAMAPi MF_00076. HisB.
InterProi IPR000807. ImidazoleglycerolP_deHydtase.
IPR020565. ImidazoleglycerP_deHydtase_CS.
IPR020568. Ribosomal_S5_D2-typ_fold.
[Graphical view ]
PANTHERi PTHR23133:SF2. PTHR23133:SF2. 1 hit.
Pfami PF00475. IGPD. 1 hit.
[Graphical view ]
SUPFAMi SSF54211. SSF54211. 2 hits.
PROSITEi PS00954. IGP_DEHYDRATASE_1. 1 hit.
PS00955. IGP_DEHYDRATASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the probiotic bacterium Bifidobacterium animalis subsp. lactis AD011."
    Kim J.F., Jeong H., Yu D.S., Choi S.-H., Hur C.-G., Park M.-S., Yoon S.H., Kim D.-W., Ji G.E., Park H.-S., Oh T.K.
    J. Bacteriol. 191:678-679(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AD011.

Entry informationi

Entry nameiHIS7_BIFA0
AccessioniPrimary (citable) accession number: B8DSW4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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