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Protein

Glycine--tRNA ligase alpha subunit

Gene

glyQ

Organism
Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciDVUL883:GCJ5-305-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine--tRNA ligase alpha subunitUniRule annotation (EC:6.1.1.14UniRule annotation)
Alternative name(s):
Glycyl-tRNA synthetase alpha subunitUniRule annotation
Short name:
GlyRSUniRule annotation
Gene namesi
Name:glyQUniRule annotation
Ordered Locus Names:DvMF_0290
OrganismiDesulfovibrio vulgaris (strain Miyazaki F / DSM 19637)
Taxonomic identifieri883 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000001361 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 291291Glycine--tRNA ligase alpha subunitPRO_1000197180Add
BLAST

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.UniRule annotation

Protein-protein interaction databases

STRINGi883.DvMF_0290.

Family & Domainsi

Sequence similaritiesi

Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108HMW. Bacteria.
COG0752. LUCA.
HOGENOMiHOG000264291.
KOiK01878.
OMAiLGSYYQF.
OrthoDBiEOG661H9S.

Family and domain databases

HAMAPiMF_00254. Gly_tRNA_synth_alpha.
InterProiIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamiPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSiPR01044. TRNASYNTHGA.
TIGRFAMsiTIGR00388. glyQ. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8DPG0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHFQDVILTL QNFWAKRGCV IMQPIDVECG AGTFNPSTFL RVIGPEPWNV
60 70 80 90 100
AYVEPSRRPT DGRYGENPNR LQHYFQFQVI LKPSPDNVQD IYLDSLRALG
110 120 130 140 150
IDPAAHDIRF VEDDWESPTL GAWGLGWEVW LNGMEVTQFT YFQQVGGIDL
160 170 180 190 200
APTSVEITYG LERLCMYLQG KESVYDLSWN DRVTYGNIYH QNEVEQSKYN
210 220 230 240 250
FEASNPKMLL DQFNACEAEC KRLCDEGLLW PAYDYCLKCS HTFNLLDARG
260 270 280 290
AISITERTGY IGRVRALASA VARLYAVQRE ELGYPMLASA R
Length:291
Mass (Da):33,267
Last modified:March 3, 2009 - v1
Checksum:i9A82BC7F55FA427E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001197 Genomic DNA. Translation: ACL07247.1.
RefSeqiWP_012611441.1. NC_011769.1.

Genome annotation databases

EnsemblBacteriaiACL07247; ACL07247; DvMF_0290.
KEGGidvm:DvMF_0290.
PATRICi21770495. VBIDesVul86729_0302.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001197 Genomic DNA. Translation: ACL07247.1.
RefSeqiWP_012611441.1. NC_011769.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi883.DvMF_0290.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL07247; ACL07247; DvMF_0290.
KEGGidvm:DvMF_0290.
PATRICi21770495. VBIDesVul86729_0302.

Phylogenomic databases

eggNOGiENOG4108HMW. Bacteria.
COG0752. LUCA.
HOGENOMiHOG000264291.
KOiK01878.
OMAiLGSYYQF.
OrthoDBiEOG661H9S.

Enzyme and pathway databases

BioCyciDVUL883:GCJ5-305-MONOMER.

Family and domain databases

HAMAPiMF_00254. Gly_tRNA_synth_alpha.
InterProiIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamiPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSiPR01044. TRNASYNTHGA.
TIGRFAMsiTIGR00388. glyQ. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Desulfovibrio vulgaris str. 'Miyazaki F'."
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Hazen T.C., Richardson P.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Miyazaki F / DSM 19637.

Entry informationi

Entry nameiSYGA_DESVM
AccessioniPrimary (citable) accession number: B8DPG0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: November 11, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.