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B8DNX4 (SYR_DESVM) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:DvMF_0850
OrganismDesulfovibrio vulgaris (strain Miyazaki F / DSM 19637) [Complete proteome] [HAMAP]
Taxonomic identifier883 [NCBI]
Taxonomic lineageBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio

Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 551551Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000198898

Regions

Motif125 – 13511"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B8DNX4 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 0B3996CD2E0E87CA

FASTA55160,466
        10         20         30         40         50         60 
MRARQQLLAS LQAIVKDMGL SWPEKATLEP PRDKSFGDLA ANIALVISKD AGVPPRELAS 

        70         80         90        100        110        120 
RLAGALRDSD PAIASVDIAG PGFLNVTYSP DFWRETVLHV EAAGDRYGAT AVGAGRKAQV 

       130        140        150        160        170        180 
EYVSANPTGP LHIGHGRGAA LGDCLARVLR FAGYDVTTEY YINDAGRQMR LLGLSVWLRA 

       190        200        210        220        230        240 
LELSGRPFTL PEDFYRGDYI KDIAAEMLAK DPGLVDLPEA EGQDRCFEYA MNSIMDGIKQ 

       250        260        270        280        290        300 
DLADFRVEHQ VWFSELSLVR EGAVEKTFER LKAAGLAFEQ DGALWFRTTT LGDDKDRVLR 

       310        320        330        340        350        360 
KSDGTLTYFA SDIAYHDNKY DRGFDLVVDI WGADHHGYVP RMRAAVAALG KRPEQFDVIL 

       370        380        390        400        410        420 
VQLVNLLQNG EQIAMSTRAG QFETLHDVVR EVGADAARFM FLSRKSDSHL DFDLELVKQR 

       430        440        450        460        470        480 
SMDNPVYYVQ YAHARVCAVL RKAAERAIVL PARLDAAALA PLTLPEELDL LRLVDRMPDT 

       490        500        510        520        530        540 
LSAAAEGLAP HHVSFYLMEV AGALHSYYAK VPVLNAADAE TIVARLALLR AVGQAVANGL 

       550 
NLLGVEAPEA M 

« Hide

References

[1]"Complete sequence of Desulfovibrio vulgaris str. 'Miyazaki F'."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Hazen T.C., Richardson P.
Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Miyazaki F / DSM 19637.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001197 Genomic DNA. Translation: ACL07806.1.
RefSeqYP_002435274.1. NC_011769.1.

3D structure databases

ProteinModelPortalB8DNX4.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING883.DvMF_0850.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL07806; ACL07806; DvMF_0850.
GeneID7172739.
KEGGdvm:DvMF_0850.
PATRIC21771689. VBIDesVul86729_0893.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycDVUL883:GCJ5-873-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_DESVM
AccessionPrimary (citable) accession number: B8DNX4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: April 16, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries