Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.

Cofactori

Mg2+Note: Binds 1 Mg2+ ion per subunit.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei20Nucleophile1
Metal bindingi20Magnesium1
Metal bindingi22Magnesium; via carbonyl oxygen1
Active sitei61Schiff-base intermediate with substrate1
Metal bindingi194Magnesium1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandMagnesium, Metal-binding, Schiff base

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolase (EC:3.11.1.1)
Short name:
Phosphonatase
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolase
Gene namesi
Name:phnX
Ordered Locus Names:DvMF_0514
OrganismiDesulfovibrio vulgaris (strain Miyazaki F / DSM 19637)
Taxonomic identifieri883 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000001361 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001448321 – 280Phosphonoacetaldehyde hydrolaseAdd BLAST280

Interactioni

Subunit structurei

Homodimer.

Protein-protein interaction databases

STRINGi883.DvMF_0514.

Structurei

3D structure databases

ProteinModelPortaliB8DKP2.
SMRiB8DKP2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.

Phylogenomic databases

eggNOGiENOG4108KAZ. Bacteria.
COG0637. LUCA.
HOGENOMiHOG000217971.
KOiK05306.
OMAiKAVIFDW.
OrthoDBiPOG091H05HY.

Family and domain databases

CDDicd02586. HAD_PHN. 1 hit.
Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 1 hit.
HAMAPiMF_01375. PhnX. 1 hit.
InterProiView protein in InterPro
IPR036412. HAD-like_sf.
IPR006439. HAD-SF_hydro_IA.
IPR023214. HAD_sf.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01549. HAD-SF-IA-v1. 1 hit.
TIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

B8DKP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPFLRTRVY DGPVRAVVLD WAGTAVDHGC LGPAAVFVQA FALHGVEVAV
60 70 80 90 100
SEAREPMGSE KREHVRRMLA MDSVAARWRA VHGHVPHEAD VDAVYRDVEP
110 120 130 140 150
LMLQTIAAHA VPVPGLAEFV DRVRGRGMGL GSCTGYTGPM MEVLVPEAAR
160 170 180 190 200
RGYSPDVVVH ASEVPAGRPY PWMCYLNAMR LGVHPMESMV KIGDTVADMH
210 220 230 240 250
EARNAGMWTV GVVRTGNDVG LSEVDAARMP PDQLAARMTV AAARLREAGA
260 270 280
HYVVDSIADC FSVIKAIEAR LARGDTPYPA
Length:280
Mass (Da):30,244
Last modified:March 3, 2009 - v1
Checksum:i102D065062AACB1E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001197 Genomic DNA. Translation: ACL07471.1.
RefSeqiWP_012611663.1. NC_011769.1.

Genome annotation databases

EnsemblBacteriaiACL07471; ACL07471; DvMF_0514.
KEGGidvm:DvMF_0514.

Similar proteinsi

Entry informationi

Entry nameiPHNX_DESVM
AccessioniPrimary (citable) accession number: B8DKP2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: October 25, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families