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B8DKP2

- PHNX_DESVM

UniProt

B8DKP2 - PHNX_DESVM

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Protein
Phosphonoacetaldehyde hydrolase
Gene
phnX, DvMF_0514
Organism
Desulfovibrio vulgaris (strain Miyazaki F / DSM 19637)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Involved in phosphonate degradation By similarity.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Binds 1 Mg2+ ion per subunit By similarity.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei20 – 201Nucleophile By similarity
Metal bindingi20 – 201Magnesium By similarity
Metal bindingi22 – 221Magnesium; via carbonyl oxygen By similarity
Active sitei61 – 611Schiff-base intermediate with substrate By similarity
Metal bindingi194 – 1941Magnesium By similarity

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphonoacetaldehyde hydrolase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. organic phosphonate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding, Schiff base

Enzyme and pathway databases

BioCyciDVUL883:GCJ5-534-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolase (EC:3.11.1.1)
Short name:
Phosphonatase
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolase
Gene namesi
Name:phnX
Ordered Locus Names:DvMF_0514
OrganismiDesulfovibrio vulgaris (strain Miyazaki F / DSM 19637)
Taxonomic identifieri883 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
ProteomesiUP000001361: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 280280Phosphonoacetaldehyde hydrolaseUniRule annotation
PRO_1000144832Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi883.DvMF_0514.

Structurei

3D structure databases

ProteinModelPortaliB8DKP2.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0637.
HOGENOMiHOG000217971.
KOiK05306.
OMAiDERNVER.
OrthoDBiEOG6ZH2FH.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01549. HAD-SF-IA-v1. 1 hit.
TIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

B8DKP2-1 [UniParc]FASTAAdd to Basket

« Hide

MKPFLRTRVY DGPVRAVVLD WAGTAVDHGC LGPAAVFVQA FALHGVEVAV    50
SEAREPMGSE KREHVRRMLA MDSVAARWRA VHGHVPHEAD VDAVYRDVEP 100
LMLQTIAAHA VPVPGLAEFV DRVRGRGMGL GSCTGYTGPM MEVLVPEAAR 150
RGYSPDVVVH ASEVPAGRPY PWMCYLNAMR LGVHPMESMV KIGDTVADMH 200
EARNAGMWTV GVVRTGNDVG LSEVDAARMP PDQLAARMTV AAARLREAGA 250
HYVVDSIADC FSVIKAIEAR LARGDTPYPA 280
Length:280
Mass (Da):30,244
Last modified:March 3, 2009 - v1
Checksum:i102D065062AACB1E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001197 Genomic DNA. Translation: ACL07471.1.
RefSeqiWP_012611663.1. NC_011769.1.
YP_002434939.1. NC_011769.1.

Genome annotation databases

EnsemblBacteriaiACL07471; ACL07471; DvMF_0514.
GeneIDi7172401.
KEGGidvm:DvMF_0514.
PATRICi21770981. VBIDesVul86729_0541.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001197 Genomic DNA. Translation: ACL07471.1 .
RefSeqi WP_012611663.1. NC_011769.1.
YP_002434939.1. NC_011769.1.

3D structure databases

ProteinModelPortali B8DKP2.
ModBasei Search...

Protein-protein interaction databases

STRINGi 883.DvMF_0514.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL07471 ; ACL07471 ; DvMF_0514 .
GeneIDi 7172401.
KEGGi dvm:DvMF_0514.
PATRICi 21770981. VBIDesVul86729_0541.

Phylogenomic databases

eggNOGi COG0637.
HOGENOMi HOG000217971.
KOi K05306.
OMAi DERNVER.
OrthoDBi EOG6ZH2FH.

Enzyme and pathway databases

BioCyci DVUL883:GCJ5-534-MONOMER.

Family and domain databases

Gene3Di 1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPi MF_01375. PhnX.
InterProi IPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view ]
Pfami PF13419. HAD_2. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01549. HAD-SF-IA-v1. 1 hit.
TIGR01422. phosphonatase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Desulfovibrio vulgaris str. 'Miyazaki F'."
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Hazen T.C., Richardson P.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Miyazaki F / DSM 19637.

Entry informationi

Entry nameiPHNX_DESVM
AccessioniPrimary (citable) accession number: B8DKP2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: September 3, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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