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B8DHF1 (B8DHF1_LISMH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arginine biosynthesis bifunctional protein ArgJ HAMAP MF_01106
Gene names
Name:argJ HAMAP MF_01106
Ordered Locus Names:LMHCC_0972
OrganismListeria monocytogenes serotype 4a (strain HCC23) [Complete proteome] [HAMAP] EMBL ACK39320.1
Taxonomic identifier552536 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate By similarity. HAMAP MF_01106

Catalytic activity

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01106

N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L-glutamate. HAMAP MF_01106

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1. HAMAP MF_01106

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01106

Subunit structure

Heterotetramer of two alpha and two beta chains By similarity. HAMAP MF_01106

Subcellular location

Cytoplasm By similarity HAMAP MF_01106.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway By similarity. HAMAP MF_01106

Sequence similarities

Belongs to the ArgJ family. HAMAP MF_01106

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Site184 – 1852Cleavage; by autolysis By similarity HAMAP MF_01106

Sequences

Sequence LengthMass (Da)Tools
B8DHF1 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 71762882BAC13AA5

FASTA39842,684
        10         20         30         40         50         60 
MELIKGNIAS PKGFYADGKH AGLKRKRNDI GWIYSEVPAN AAAVYTMNQM QAAPIFVTKD 

        70         80         90        100        110        120 
SFQSSAKLQA IIVNSGNANA CTGNQGMLDA LAMRAQTAEK LDIPLDYVAV ASTGIIGDML 

       130        140        150        160        170        180 
PMDKINAGIE MLEKQTGNAA DFEEAILTTD TFQKQISFQT EIGGKTVTMS GVAKGSGMIH 

       190        200        210        220        230        240 
PNMATMLAFI TTDAAIPAEL LQKLLKIKVD KTFNQITVDG DTSTNDMVVV MANGCAENPK 

       250        260        270        280        290        300 
LQEGTADFAK FADMFQAVTE HLAKSIARDG EGATKLIEVQ VNGATKTEDA RMIAKKIVSS 

       310        320        330        340        350        360 
SLVKTAAFGG DGNWGRIICA IGYSGGRFAP DNITIKIGGI EILNHSSQTI FNQQALDAYL 

       370        380        390 
EEEHIVIEVD LHIGLESGTA WGCDLSYEYV KINACYRT

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References

[1]"Genome sequence of lineage III Listeria monocytogenes strain HCC23."
Steele C.L., Donaldson J.R., Paul D., Banes M.M., Arick T., Bridges S.M., Lawrence M.L.
J. Bacteriol. 193:3679-3680(2011) [PubMed: 21602330] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HCC23.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001175 Genomic DNA. Translation: ACK39320.1.
RefSeqYP_002349934.1. NC_011660.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB8DHF1.

Protein family/group databases

MEROPST05.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7080153.
GenomeReviewsGene locus LMHCC_0972 in contig CP001175_GR.
KEGGlmh:LMHCC_0972.
PATRIC20317061. VBILisMon86872_0961.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284202.
OMAGRDPNWG.
ProtClustDBPRK05388.

Family and domain databases

HAMAPMF_01106. ArgJ.
[Tree]
InterProIPR002813. Arg_biosynth_ArgJ.
IPR016117. Pept_S58_DmpA/Arg_biosyn_ArgJ.
[Graphical view]
KOK00620.
PANTHERPTHR23100. ArgJ. 1 hit.
PfamPF01960. ArgJ. 1 hit.
[Graphical view]
ProDomPD004193. Arg_biosynth_ArgJ. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56266. Pept_S58_DmpA/Arg_biosyn_ArgJ. 1 hit.
TIGRFAMsTIGR00120. ArgJ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8DHF1_LISMH
AccessionPrimary (citable) accession number: B8DHF1
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info