Skip Header

Contribute Send feedback
Read comments (?) or add your own

B8DBZ9 (AROB_LISMH) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 22. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:LMHCC_0629
OrganismListeria monocytogenes serotype 4a (strain HCC23) [Complete proteome] [HAMAP]
Taxonomic identifier552536 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length365 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm By similarity HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3653653-dehydroquinate synthase HAMAP MF_00110
PRO_1000119084

Sequences

Sequence LengthMass (Da)Tools
B8DBZ9 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: DBDB87B00F5A4CCA

FASTA36541,142
        10         20         30         40         50         60 
MPEITVRAKS KTYPVYINEF ALEDVREKWT ESLAKFSHVF VLTDEHVAEL HKAKLDAVLA 

        70         80         90        100        110        120 
DLPVVTYYVA PNGEEAKTFR VYEDVMTKLI ETGLDRKAVL IAFGGGVIGD LGGFVAATYM 

       130        140        150        160        170        180 
RGIPFYQVPT TVLAHDSAVG GKVAINHPLG KNMIGNFYQP EAVIYDTQFF ATLPEREMRS 

       190        200        210        220        230        240 
GFAEMIKHAL ISDQTLLRAL MDTFTEPKDF YTKDLTPFLQ RGIEIKANIV AQDETEQGVR 

       250        260        270        280        290        300 
AYLNFGHTFG HALEAYGNFG KWLHGEAITY GMIYALTMSE AIYGLDFDLA EFKTWLKQLG 

       310        320        330        340        350        360 
YDTTFDATVP FSKILENMRH DKKTTFNEIS MVLLEEIGKP VIFKAEDDLI FETYKRVMRN 


GGNGI

« Hide

References

[1]"Genome sequence of lineage III Listeria monocytogenes strain HCC23."
Steele C.L., Donaldson J.R., Paul D., Banes M.M., Arick T., Bridges S.M., Lawrence M.L.
J. Bacteriol. 193:3679-3680(2011) [PubMed: 21602330] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HCC23.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001175 Genomic DNA. Translation: ACK38985.1.
RefSeqYP_002349599.1. NC_011660.1.

3D structure databases

ProteinModelPortalB8DBZ9.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8DBZ9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7079007.
GenomeReviewsGene locus LMHCC_0629 in contig CP001175_GR.
KEGGlmh:LMHCC_0629.
PATRIC20316328. VBILisMon86872_0623.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG632303.
OMAAYLNFGH.
ProtClustDBPRK00002.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_LISMH
AccessionPrimary (citable) accession number: B8DBZ9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents