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B8D9M8 (PGK_BUCA5) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length390 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 390390Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000192811

Regions

Nucleotide binding340 – 3434ATP By similarity
Region21 – 233Substrate binding By similarity
Region59 – 624Substrate binding By similarity

Sites

Binding site361Substrate By similarity
Binding site1141Substrate By similarity
Binding site1471Substrate By similarity
Binding site1981ATP By similarity
Binding site3141ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
B8D9M8 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 153FDD49D2C0B385

FASTA39043,669
        10         20         30         40         50         60 
MTIRKMTELN ITEKRILIRS DLNVPIENGI IQSDARILAA LPTIELALQK KAKVIIMSHL 

        70         80         90        100        110        120 
GRPKEGYYTK KYSLFPIFEY FKKKFNNTKI YFSNNFLDGI KLNPGEIALL ENTRFNKGEL 

       130        140        150        160        170        180 
NNDEQLSKKY SDLCDIFVMD AFGSSHRMQS STYGIGKFVK IACAGLLLIS EIDALKKALK 

       190        200        210        220        230        240 
KPKRPMVAIV GGSKVSTKFN VLNKLSKIAD TIIVGGGIAN TFLAIDYKIG KSLYEPDFVF 

       250        260        270        280        290        300 
EAKKLRDKYN IIVPIDSRVG KNFCKNEQAI IKSPDNIKED EEIMDFGDES IKKIISIITQ 

       310        320        330        340        350        360 
SQTIMWNGPV GVFEFPNFRK GTEMIAKTIA NSNAFSIAGG GDTLSVIDMF NIKNNISYIS 

       370        380        390 
TGGGAFLEFI EGKKLPAIQM LEENFKNKSK 

« Hide

References

[1]"The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria."
Moran N.A., McLaughlin H.J., Sorek R.
Science 323:379-382(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 5A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001161 Genomic DNA. Translation: ACL30799.1.
RefSeqYP_002468187.1. NC_011833.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING107806.BU450.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL30799; ACL30799; BUAP5A_443.
GeneID7262461.
KEGGbap:BUAP5A_443.
PATRIC21243153. VBIBucAph51993_0445.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAAGHPVGK.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

BioCycBAPH563178:GHDF-443-MONOMER.
UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
ProtoNetSearch...

Entry information

Entry namePGK_BUCA5
AccessionPrimary (citable) accession number: B8D9M8
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: June 11, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways