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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:BUAP5A_238
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A)
Taxonomic identifieri563178 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001988791 – 574Arginine--tRNA ligaseAdd BLAST574

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB8D940.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi121 – 131"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

B8D940-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLKNTIKED IQDALIKIAI INCDPVITLN KKTKIGHYQL NNLIKIANIS
60 70 80 90 100
NLKPFELANR IILNIKKKYM YKEITFSQPG FINFLINPYW ISEQLEKIFL
110 120 130 140 150
SPRLGINHVN AQNIVIDYSS PNIAKEMHIG HLRSTIIGDV MARILDFLGH
160 170 180 190 200
NVIRANHIGD WGTQFGMLIA YLEVKKLVNS PLSLMKLEEY YCKAKKKYDI
210 220 230 240 250
DQLFAEKSRE YVVKLQNGDQ YCYSIWKKLV SITMLENCKI YKRLHVTLKK
260 270 280 290 300
KHTMGESIYN KMLPNIIEDL KNKKIAIEKN GSTIVFLKEF KNRLGEPMGV
310 320 330 340 350
VIQKKDKGFL YSTTDIACLK YRYQVLHADR IIYYTDSRQH QHLLQAWTIA
360 370 380 390 400
KKALYISQNL LLEHHIFGMM LSKDKRPFKT RDGDTIKLSA LLDEATERAM
410 420 430 440 450
RLIKNKQPNL SKKKLNQLSN IIGVGAVKYA DLSKNRNTNY IFDWNEMLSF
460 470 480 490 500
EGNTAPYIQY AYTRIVSILK KSNMPIKKLK EKIFLTKESE INLAIKILEF
510 520 530 540 550
EEIILLISQK GTPHILCKYL YHLATSFSHF YENCSILFPK KIKTCKSRLK
560 570
LSILTAKTLK KGLNMLGIRV VKKM
Length:574
Mass (Da):66,686
Last modified:March 3, 2009 - v1
Checksum:i7916BD29FCAB02C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001161 Genomic DNA. Translation: ACL30611.1.
RefSeqiWP_009874199.1. NC_011833.1.

Genome annotation databases

EnsemblBacteriaiACL30611; ACL30611; BUAP5A_238.
KEGGibap:BUAP5A_238.

Similar proteinsi

Entry informationi

Entry nameiSYR_BUCA5
AccessioniPrimary (citable) accession number: B8D940
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: August 30, 2017
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families