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B8D8S5 (B8D8S5_BUCA5) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospho-2-dehydro-3-deoxyheptonate aldolase PIRNR PIRNR001361
EC=2.5.1.54 PIRNR PIRNR001361
Alternative name(s):
3-deoxy-D-arabino-heptulosonate 7-phosphate synthase PIRNR PIRNR001361
DAHP synthase PIRNR PIRNR001361
Phospho-2-keto-3-deoxyheptonate aldolase PIRNR PIRNR001361
Gene names
Name:aroH EMBL ACL30497.1
Ordered Locus Names:BUAP5A_122
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain 5A) [Complete proteome] [HAMAP]
Taxonomic identifier563178 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length348 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) By similarity. PIRNR PIRNR001361

Catalytic activity

Phosphoenolpyruvate + D-erythrose 4-phosphate + H2O = 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate + phosphate. PIRNR PIRNR001361

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7. PIRNR PIRNR001361

Sequence similarities

Belongs to the class-I DAHP synthase family. PIRNR PIRNR001361

Sequences

Sequence LengthMass (Da)Tools
B8D8S5 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 8CCB7E8733D6DAF7

FASTA34838,889
        10         20         30         40         50         60 
MKKTDELRTI RIDPLITPAE LARQYAITSD IMDTVIATRQ NIARIMTGQD ARLLVVIGPC 

        70         80         90        100        110        120 
SVHDPIAAVE YAHRLYELRV KYKDRLEIIM RTYFEKPRTV VGWKGLISDP DLNGSFRVNH 

       130        140        150        160        170        180 
GLAVARKLLL DINALGMPAA TEFLDIVIGQ FIADLISWGA IGARTTESQI HREMASALSC 

       190        200        210        220        230        240 
PVGFKNGTDG NIRIAIDAIR AAKVRHLFFA PNKDGQMTIN HTSGNPYGHI IMRGGRAPNY 

       250        260        270        280        290        300 
HPDDINSAVK HLREFDLLEH LMIDFSHGNC LKEHLRQKNV SKSVSYQISH GSKAIFGVMI 

       310        320        330        340 
ESFLEEGFQT VTNNQPLIYG KSITDACLNW KDSVLIIEQL ADAVDARF

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References

[1]"The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria."
Moran N.A., McLaughlin H.J., Sorek R.
Science 323:379-382(2009) [PubMed: 19150844] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 5A.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001161 Genomic DNA. Translation: ACL30497.1.
RefSeqYP_002467884.1. NC_011833.1.

3D structure databases

ProteinModelPortalB8D8S5.
SMRB8D8S5. Positions 6-347.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8D8S5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBUCT00000000839; EBBUCP00000000794; EBBUCG00000000839.
GeneID7262810.
GenomeReviewsGene locus BUAP5A_122 in contig CP001161_GR.
KEGGbap:BUAP5A_122.
PATRIC21242477. VBIBucAph51993_0120.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000008184.
OMAHRELASH.
ProtClustDBPRK09261.

Family and domain databases

InterProIPR013785. Aldolase_TIM.
IPR006218. DAHP1/KDSA.
IPR006219. DHAP_synth_1.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01626.
PANTHERPTHR21225. AroFGH. 1 hit.
PfamPF00793. DAHP_synth_1. 1 hit.
[Graphical view]
PIRSFPIRSF001361. DAHP_synthase. 1 hit.
TIGRFAMsTIGR00034. AroFGH. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8D8S5_BUCA5
AccessionPrimary (citable) accession number: B8D8S5
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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