B8D878 (MURI_BUCAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glutamate racemase
EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	BUAPTUC7_548

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7) [Complete proteome] [HAMAP]

Taxonomic identifier

561501 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	262 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 262	262	Glutamate racemase HAMAP MF_00258		PRO_1000125605

Sequences

	Sequence		Length	Mass (Da)
	B8D878 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 2E0A1303A7E6E64D	FASTA	262	30,061
	10 20 30 40 50 60 MLIFDSGVGG LSILKNIKKI LPNIHYIYML DNESFPYGNK TEFFIIQRSI KIIHTIKKIY 70 80 90 100 110 120 PINIVVIACN TISTVALSIL REKFDIPIFG IFPHIKAAEK ITKNKIIGLI ATKATINSSY 130 140 150 160 170 180 TQKIIYEYSC SNTIKIIGTN KLAVIAEKKI RGVAVSQKKL KNIFRPWINL PTCPDTIILG 190 200 210 220 230 240 CTHFSLLEKE IKNILYKTRS VYFIDSIKKV IFQIKSCLKT SNVNQKIKKN IFLYSKNNNN 250 260 LKKLLSFLKQ YKFTVIKHIN LN

References

[1]	"The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria." Moran N.A., McLaughlin H.J., Sorek R. Science 323:379-382(2009) [PubMed: 19150844] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuc7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001158 Genomic DNA. Translation: ACL30343.1.
RefSeq	YP_002468838.1. NC_011834.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B8D878.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000001644; EBBUCP00000001514; EBBUCG00000001644.
GeneID	7262872.
GenomeReviews	Gene locus BUAPTUC7_548 in contig CP001158_GR.
KEGG	bau:BUAPTUC7_548.
PATRIC	21249205. VBIBucAph26317_0542.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000007930.
HOGENOM	HBG645102.
OMA	ATINSSY.
ProtClustDB	CLSK316489.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
KO	K01776.
PANTHER	PTHR21198. PTHR21198. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
SUPFAM	SSF53681. Asp/Glu_race. 2 hits.
TIGRFAMs	TIGR00067. Glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. False negative. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_BUCAT

Accession

Primary (citable) accession number: B8D878

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program