B8D7Y6 (B8D7Y6_BUCAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
N-acetylglutamate synthase EMBL ACL30251.1
EC=2.3.1.1 EMBL ACL30251.1

Gene names

Name:	argA EMBL ACL30251.1
Ordered Locus Names:	BUAPTUC7_450

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7) [Complete proteome] [HAMAP]

Taxonomic identifier

561501 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	442 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. SAAS SAAS010167
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. SAAS SAAS010167
Subcellular location	Cytoplasm By similarity SAAS SAAS010167.
Sequence similarities	Contains 1 N-acetyltransferase domain. SAAS SAAS010167

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis SAAS SAAS010167
Cellular component	Cytoplasm SAAS SAAS010167
Molecular function	Acyltransferase SAAS SAAS010167 EMBL ACL30251.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acetyl-CoA:L-glutamate N-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8D7Y6 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: C7F67E99C285A394	FASTA	442	49,226
	10 20 30 40 50 60 MKERNTELVQ GFRHSVPYIN AHRGKTFVIM LGGEAIKYGN FYSIINDIGL LHSLGIRLVV 70 80 90 100 110 120 VYGACPQINT SLKEKNIKII YHKSIRITDL ASLEQVKQAA GKLQLDITAR LSMSLTNTPL 130 140 150 160 170 180 QGANISVVSG NFIISQPLGV DDGVDYCHSG RVRRIDKNAI NCQLNNGAIV LIGPVAVSVT 190 200 210 220 230 240 GESFNLTSEE IATQVSIELK AEKMIGFCGN QGVINDEGKI ISELLSNDIK NIIKKLEKKG 250 260 270 280 290 300 DYISSTVRFL KGSIKACKSG VNRSHLISYH KSGALLQELF SRDGIGTQMV MESAEKIRGA 310 320 330 340 350 360 SINDIGGILE LIRPLEHKGI LVRRSREQLE IEVDKFTIIE HDNLTIACAA LYPFFKEKIG 370 380 390 400 410 420 EMACLAVHPD YRNSSRGDAL LKKIKMNAKD MHLKRIFVLT TQSIHWFQER GFILVDIEVL 430 440 PESKKKMYNY QRGSKILMID VI

References

[1]	"The dynamics and time scale of ongoing genomic erosion in symbiotic bacteria." Moran N.A., McLaughlin H.J., Sorek R. Science 323:379-382(2009) [PubMed: 19150844] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuc7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001158 Genomic DNA. Translation: ACL30251.1.
RefSeq	YP_002468746.1. NC_011834.1.
3D structure databases
ProteinModelPortal	B8D7Y6.
ModBase	Search...
Protein-protein interaction databases
STRING	B8D7Y6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000001929; EBBUCP00000001799; EBBUCG00000001929.
GeneID	7263171.
GenomeReviews	Gene locus BUAPTUC7_450 in contig CP001158_GR.
KEGG	bau:BUAPTUC7_450.
PATRIC	21249009. VBIBucAph26317_0450.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000007812.
HOGENOM	HBG545264.
OMA	AFNLAME.
ProtClustDB	PRK05279.
Family and domain databases
HAMAP	MF_01105. N_acetyl_glu_synth. [Tree]
InterPro	IPR000182. AcTrfase_GCN5-related_dom. IPR016181. Acyl_CoA_acyltransferase. IPR001048. Asp/Glu/Uridylate_kinase. IPR010167. NH2A_AcTrfase_ArgA. [Graphical view]
Gene3D	G3DSA:3.40.1160.10. Aa_kinase. 1 hit. G3DSA:3.40.630.30. Acyl_CoA_acyltransferase. 1 hit.
KO	K14682.
Pfam	PF00696. AA_kinase. 1 hit. PF00583. Acetyltransf_1. 1 hit. [Graphical view]
PIRSF	PIRSF000423. ArgA. 1 hit.
SUPFAM	SSF53633. Aa_kinase. 1 hit. SSF55729. Acyl_CoA_acyltransferase. 1 hit.
TIGRFAMs	TIGR01890. N-Ac-Glu-synth. 1 hit.
PROSITE	PS51186. GNAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8D7Y6_BUCAT

Accession

Primary (citable) accession number: B8D7Y6

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)