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Protein

Glutamine--tRNA ligase

Gene

glnS

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei68L-glutamineUniRule annotation1
Binding sitei213L-glutamineUniRule annotation1
Binding sitei232ATPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi36 – 38ATPUniRule annotation3
Nucleotide bindingi42 – 48ATPUniRule annotation7
Nucleotide bindingi262 – 263ATPUniRule annotation2
Nucleotide bindingi270 – 272ATPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBAPH561501:G1GCT-426-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnSUniRule annotation
Ordered Locus Names:BUAPTUC7_409
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain Tuc7)
Taxonomic identifieri561501 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesErwiniaceaeBuchnera

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001990921 – 571Glutamine--tRNA ligaseAdd BLAST571

Proteomic databases

PRIDEiB8D7U5

Interactioni

Subunit structurei

Monomer.UniRule annotation

Structurei

3D structure databases

SMRiB8D7U5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi35 – 45"HIGH" regionUniRule annotationAdd BLAST11
Motifi269 – 273"KMSKS" regionUniRule annotation5

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000259232
KOiK01886
OMAiVTHSICT

Family and domain databases

Gene3Di1.10.1160.10, 1 hit
2.40.240.10, 3 hits
3.40.50.620, 2 hits
HAMAPiMF_00126 Gln_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR004514 Gln-tRNA-synth
IPR022861 Gln_tRNA_ligase_bac
IPR000924 Glu/Gln-tRNA-synth
IPR020058 Glu/Gln-tRNA-synth_Ib_cat-dom
IPR020059 Glu/Gln-tRNA-synth_Ib_codon-bd
IPR020061 Glu_tRNA_lig_a-bdl
IPR020056 Rbsml_L25/Gln-tRNA_synth_N
IPR011035 Ribosomal_L25/Gln-tRNA_synth
IPR014729 Rossmann-like_a/b/a_fold
PfamiView protein in Pfam
PF00749 tRNA-synt_1c, 1 hit
PF03950 tRNA-synt_1c_C, 1 hit
PRINTSiPR00987 TRNASYNTHGLU
SUPFAMiSSF50715 SSF50715, 1 hit
TIGRFAMsiTIGR00440 glnS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

B8D7U5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDTKKEIKNN NFICQIINKD LNENKNLSFY TRFPPEPNGY LHIGHAKSIC
60 70 80 90 100
LNFELASLYK GRCNLRFDDT NPLKENIKYI KSIKHDINWL GYKWHGNVRY
110 120 130 140 150
ASEYFLKLYQ YAQELIKKGL AYVDHLTKEQ IREYRGTLNT PGKNSPYRNR
160 170 180 190 200
TIQENIELFE KMKKGDFSEG EACLRAKINM SSSSIIMRDP VLYRIIFIKH
210 220 230 240 250
HQTQNKWCIY PMYDFAHCLS DSIEGITHSL CTLEFQDNKF LYNWILKNTS
260 270 280 290 300
VKHYPKQYEF SRLNLEFSIL SKRKIKILID KNIIEGWDDP RIPTLSALRR
310 320 330 340 350
KGYTPSSIKN FCQKIGVTKQ NNLIEFSMLE HCIRKELNQT AIRTMAILDP
360 370 380 390 400
IKIFLYNLDS NYKEEFIVPN HPNNPEMGTH KIIFTNTIYI DRSDFKEKYD
410 420 430 440 450
KKYKRLKLGE KIRLRYSYII HAEKIEKDEY GNISNIICYC DLNTLGRKPK
460 470 480 490 500
DNKNPAVIHW ISEKNTLSAE FKLYDQLFNI KNPEQQENFL LYINSKSLIK
510 520 530 540 550
KFGFIEKKIG EEIQKKISNN NIEIFFQFER IGYFCIDFID SKKNQLVFNR
560 570
TVGLRDTWDS KKIKTKNITN N
Length:571
Mass (Da):67,834
Last modified:March 3, 2009 - v1
Checksum:i1564C165FB5B5D84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001158 Genomic DNA Translation: ACL30210.1
RefSeqiWP_012619537.1, NC_011834.1

Genome annotation databases

EnsemblBacteriaiACL30210; ACL30210; BUAPTUC7_409
KEGGibau:BUAPTUC7_409

Similar proteinsi

Entry informationi

Entry nameiSYQ_BUCAT
AccessioniPrimary (citable) accession number: B8D7U5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 57 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

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