B8D6B9 (B8D6B9_DESK1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Probable exosome complex exonuclease 1 HAMAP MF_00591
EC=3.1.13.- HAMAP MF_00591

Gene names

Ordered Locus Names:

DKAM_1324

Organism

Desulfurococcus kamchatkensis (strain 1221n / DSM 18924) [Complete proteome] [HAMAP]

Taxonomic identifier

490899 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Desulfurococcus

Protein attributes

Sequence length	242 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably involved in the 3'->5' degradation of a variety of RNA species By similarity. HAMAP MF_00591
Subunit structure	Component of the archaeal exosome multienzyme ribonuclease complex By similarity. HAMAP MF_00591
Subcellular location	Cytoplasm By similarity HAMAP MF_00591.
Sequence similarities	Belongs to the RNase PH family. HAMAP MF_00591

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00591 Exosome HAMAP MF_00591
Molecular function	Exonuclease HAMAP MF_00591 EMBL ACL11650.1 Hydrolase Nuclease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	RNA catabolic process Inferred from electronic annotation. Source: HAMAP RNA processing Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell exosome (RNase complex) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	3'-5'-exoribonuclease activity Inferred from electronic annotation. Source: HAMAP RNA binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8D6B9 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: ECC9B8729E774801	FASTA	242	26,558
	10 20 30 40 50 60 MSGKPVLIRD GLRIDGRKPE ELRPVRIALG VLKNANGSAL VEYGNTKALA AVYGPREALP 70 80 90 100 110 120 KHISLPDRAI LRVRYHMAPF STTERKSPAP SRREIELSKV IREALESVVF TSQFPRASID 130 140 150 160 170 180 VFIEILQADG GTRTTGLTAA SLALADAGIP MRDLVIGVAV GKVDGVLVLD INELEDEYGE 190 200 210 220 230 240 ADLPVGIMPN TGEIVLLQLN GVLTSGEFKQ ALDMAYKGVE QIYKTAKEAM YRKYYKMFEE VR

References

[1]

"Complete genome sequence of the anaerobic, protein-degrading hyperthermophilic crenarchaeon Desulfurococcus kamchatkensis." Ravin N.V., Mardanov A.V., Beletsky A.V., Kublanov I.V., Kolganova T.V., Lebedinsky A.V., Chernyh N.A., Bonch-Osmolovskaya E.A., Skryabin K.G. J. Bacteriol. 191:2371-2379(2009) [PubMed: 19114480] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001140 Genomic DNA. Translation: ACL11650.1.
RefSeq	YP_002429017.1. NC_011766.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B8D6B9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7171375.
GenomeReviews	Gene locus DKAM_1324 in contig CP001140_GR.
KEGG	dka:DKAM_1324.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG737187.
OMA	HMAPFST.
ProtClustDB	CLSK734197.
Family and domain databases
HAMAP	MF_00591. Exosome_Exonucl_1. [Tree]
InterPro	IPR011807. ExoRNase_exosome_complex. IPR001247. ExoRNase_PH_dom1. IPR015847. ExoRNase_PH_dom2. IPR020568. Ribosomal_S5_D2-typ_fold. [Graphical view]
KO	K11600.
Pfam	PF01138. RNase_PH. 1 hit. PF03725. RNase_PH_C. 1 hit. [Graphical view]
SUPFAM	SSF55666. 3_ExoRNase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit.
TIGRFAMs	TIGR02065. ECX1. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8D6B9_DESK1

Accession

Primary (citable) accession number: B8D6B9

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	November 16, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)