B8D5W2 (RNP1_DESK1) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 1
Short name=RNase P component 1
EC=3.1.26.5

Gene names

Name:	rnp1
Ordered Locus Names:	DKAM_1167

Organism

Desulfurococcus kamchatkensis (strain 1221n / DSM 18924) [Complete proteome] [HAMAP]

Taxonomic identifier

490899 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Desulfurococcus › Desulfurococcus kamchatkensis

Protein attributes

Sequence length	92 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00754
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00754
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	mRNA cleavage Inferred from electronic annotation. Source: InterPro rRNA processing Inferred from electronic annotation. Source: InterPro tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribonuclease MRP complex Inferred from electronic annotation. Source: InterPro ribonuclease P complex Inferred from electronic annotation. Source: InterPro
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 92	92	Ribonuclease P protein component 1 HAMAP-Rule MF_00754		PRO_1000148362

Sequences

	Sequence		Length	Mass (Da)
	B8D5W2 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 383D9151C2CAF52A	FASTA	92	10,478
	10 20 30 40 50 60 MRVNSRNIAY HELIGLEVRI LQYPDPSLVG LKGKVVDETL KTLVIETPSG RRVRIFKFNS 70 80 90 ILEFMLPDGE AVVIKGSTII GRPWDRLKMV SR

References

[1]

"Complete genome sequence of the anaerobic, protein-degrading hyperthermophilic crenarchaeon Desulfurococcus kamchatkensis." Ravin N.V., Mardanov A.V., Beletsky A.V., Kublanov I.V., Kolganova T.V., Lebedinsky A.V., Chernyh N.A., Bonch-Osmolovskaya E.A., Skryabin K.G. J. Bacteriol. 191:2371-2379(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1221n / DSM 18924.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001140 Genomic DNA. Translation: ACL11493.1.
RefSeq	YP_002428860.1. NC_011766.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	490899.DKAM_1167.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACL11493; ACL11493; DKAM_1167.
GeneID	7171641.
KEGG	dka:DKAM_1167.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1588.
HOGENOM	HOG000231353.
KO	K03538.
OMA	RILQYPD.
ProtClustDB	CLSK965769.
Enzyme and pathway databases
BioCyc	DKAM490899:GHYH-1199-MONOMER.
Family and domain databases
Gene3D	2.30.30.210. 1 hit.
HAMAP	MF_00754. RNase_P_1.
InterPro	IPR002730. RNase_P/MRP_p29. IPR023538. RNase_P_comp-1. IPR023534. Rof/RNase_P-like. [Graphical view]
Pfam	PF01868. UPF0086. 1 hit. [Graphical view]
SUPFAM	SSF101744. RNase_P_Rpp29. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP1_DESK1

Accession

Primary (citable) accession number: B8D5W2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program