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B8D418 (B8D418_DESK1) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Amidophosphoribosyltransferase PIRNR PIRNR000485
Short name=ATase PIRNR PIRNR000485
EC=2.4.2.14 PIRNR PIRNR000485
Alternative name(s):
Glutamine phosphoribosylpyrophosphate amidotransferase PIRNR PIRNR000485
Gene names
Ordered Locus Names:DKAM_0523
OrganismDesulfurococcus kamchatkensis (strain 1221n / DSM 18924) [Complete proteome] [HAMAP]
Taxonomic identifier490899 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Desulfurococcus

Protein attributes

Sequence length456 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

5-phospho-beta-D-ribosylamine + diphosphate + L-glutamate = L-glutamine + 5-phospho-alpha-D-ribose 1-diphosphate + H2O. PIRNR PIRNR000485

Cofactor

Binds 1 4Fe-4S cluster per subunit By similarity. PIRSR PIRSR000485-3

Binds 1 magnesium ion per subunit By similarity. PIRNR PIRNR000485

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2. PIRNR PIRNR000485

Sequence similarities

In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. PIRNR PIRNR000485

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding2371Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding3831Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4321Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3
Metal binding4351Iron-sulfur (4Fe-4S) By similarity PIRSR PIRSR000485-3

Sequences

Sequence LengthMass (Da)Tools
B8D418 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: DBCCFF0D40613A15

FASTA45649,974
        10         20         30         40         50         60 
MGRGDHFRIL VELLLELQHR GQEAAGIVLF DMEAKRFVRL AGSGVVGNLL LKDSARNISI 

        70         80         90        100        110        120 
ESAQGRYYGG VGHVRYATTG GYWGAVIQPI IVNTGGLNFS LAFNGTIANY RLIADEIRVK 

       130        140        150        160        170        180 
ASNDSRVLGY LISELSREYR GDIVEAARHL SEYVIGGYSL IVLTNEPRII IARDPAGYRP 

       190        200        210        220        230        240 
LSYSLHGEDF YVASETAALE VIGAGEWSEV KPGEVISFDG FSLEKYMTGS VGTPYPCVFE 

       250        260        270        280        290        300 
YIYFSRPDSV FNGVSVYEAR YRMGKELAGL INGIEVDMVV PVPDTGRIPA LGLSETLGLH 

       310        320        330        340        350        360 
LEEAVIVNKY MGRGFITPPS HRSMVAKLKY NVVRNRVIGK RILLVEDSIV RGTTLNHLVS 

       370        380        390        400        410        420 
KLRYAGASKV HIGVVSPPFK YPCFMGIDIP AKNELIAGDL TPEEVARRLG ADSVIYNTIE 

       430        440        450 
GLGKAVGSPS LCMACFTGRY AFRGLSLEDL ENMVKR

« Hide

References

[1]"Complete genome sequence of the anaerobic, protein-degrading hyperthermophilic crenarchaeon Desulfurococcus kamchatkensis."
Ravin N.V., Mardanov A.V., Beletsky A.V., Kublanov I.V., Kolganova T.V., Lebedinsky A.V., Chernyh N.A., Bonch-Osmolovskaya E.A., Skryabin K.G.
J. Bacteriol. 191:2371-2379(2009) [PubMed: 19114480] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001140 Genomic DNA. Translation: ACL10849.1.
RefSeqYP_002428216.1. NC_011766.1.

3D structure databases

ProteinModelPortalB8D418.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8D418.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7170744.
GenomeReviewsGene locus DKAM_0523 in contig CP001140_GR.
KEGGdka:DKAM_0523.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG392416.
OMADSMFEDQ.
ProtClustDBCLSK2805609.

Family and domain databases

InterProIPR005854. Amd_phspho_trans.
IPR017932. GATase_II.
IPR000836. PRibTrfase.
[Graphical view]
KOK00764.
PANTHERPTHR11907. Amd_phspho_trans. 1 hit.
PfamPF00156. Pribosyltran. 1 hit.
[Graphical view]
PIRSFPIRSF000485. Amd_phspho_trans. 1 hit.
PROSITEPS51278. GATASE_TYPE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8D418_DESK1
AccessionPrimary (citable) accession number: B8D418
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info