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B8D413 (B8D413_DESK1) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Adenylosuccinate synthetase RuleBase RU000520
EC=6.3.4.4 RuleBase RU000520
Gene names
Ordered Locus Names:DKAM_0518
OrganismDesulfurococcus kamchatkensis (strain 1221n / DSM 18924) [Complete proteome] [HAMAP]
Taxonomic identifier490899 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Desulfurococcus

Protein attributes

Sequence length342 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plays an important role in the de novo pathway of purine nucleotide biosynthesis By similarity. RuleBase RU000520

Catalytic activity

GTP + IMP + L-aspartate = GDP + phosphate + N(6)-(1,2-dicarboxyethyl)-AMP. RuleBase RU000520

Pathway

Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2. RuleBase RU000520

Sequence similarities

Belongs to the adenylosuccinate synthetase family. RuleBase RU004163

Sequences

Sequence LengthMass (Da)Tools
B8D413 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 20A015BFAE3AFD46

FASTA34237,650
        10         20         30         40         50         60 
MRDMPSLIIV GGFFGDEGKG KIAAYLALSD KPVIIVRTGS INAGHTVVFN GKTFKLRAVP 

        70         80         90        100        110        120 
SGFISRDSRL LIAPGALVKL DILFKEITET GTRGRVFLDY NTGIIEERHV EAELADQYFS 

       130        140        150        160        170        180 
QVIGSTLQGV GAAMIDRVAR RLKLARDFEE LKETTIDVPG AVNEALSRGE LVHVEGTQGS 

       190        200        210        220        230        240 
FLSLYHGTYP YVTSRDTTAS AVASEVGLGP KHVDDVVVVF KAYITRVGNG PLPGELSHSE 

       250        260        270        280        290        300 
TLKLGWVEEA TVTRRIRRVA PFSIELARRA IMLNSATQIA LTKLDVLYRE SRGCREWSCL 

       310        320        330        340 
PVEARKWVEH VEDSLKTPVS LIGTCEEVNC VIDRRRELGL LR

« Hide

References

[1]"Complete genome sequence of the anaerobic, protein-degrading hyperthermophilic crenarchaeon Desulfurococcus kamchatkensis."
Ravin N.V., Mardanov A.V., Beletsky A.V., Kublanov I.V., Kolganova T.V., Lebedinsky A.V., Chernyh N.A., Bonch-Osmolovskaya E.A., Skryabin K.G.
J. Bacteriol. 191:2371-2379(2009) [PubMed: 19114480] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001140 Genomic DNA. Translation: ACL10844.1.
RefSeqYP_002428211.1. NC_011766.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB8D413.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7170739.
GenomeReviewsGene locus DKAM_0518 in contig CP001140_GR.
KEGGdka:DKAM_0518.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG658237.
OMAYVLGIIK.
ProtClustDBPRK04293.

Family and domain databases

HAMAPMF_00011. Adenylosucc_synth.
[Tree]
InterProIPR018220. Adenylosuccinate_synthase_AS.
IPR001114. Adenylosuccinate_synthetase.
[Graphical view]
KOK01939.
PANTHERPTHR11846. Asucc_synthtase. 1 hit.
PfamPF00709. Adenylsucc_synt. 2 hits.
[Graphical view]
SMARTSM00788. Adenylsucc_synt. 1 hit.
[Graphical view]
PROSITEPS01266. ADENYLOSUCCIN_SYN_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8D413_DESK1
AccessionPrimary (citable) accession number: B8D413
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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