B8D2P4 (B8D2P4_DESK1) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Aminomethyltransferase RuleBase RU003981
EC=2.1.2.10 RuleBase RU003981

Gene names

Ordered Locus Names:

DKAM_0299

Organism

Desulfurococcus kamchatkensis (strain 1221n / DSM 18924) [Complete proteome] [HAMAP] EMBL ACL10625.1

Taxonomic identifier

490899 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Crenarchaeota › Thermoprotei › Desulfurococcales › Desulfurococcaceae › Desulfurococcus › Desulfurococcus kamchatkensis

Protein attributes

Sequence length	369 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The glycine cleavage system catalyzes the degradation of glycine By similarity. RuleBase RU003981
Catalytic activity	[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. RuleBase RU003981
Subunit structure	The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. RuleBase RU003981
Sequence similarities	Belongs to the GcvT family. RuleBase RU003980

Ontologies

Keywords
Molecular function	Aminotransferase RuleBase RU003981 Methyltransferase EMBL ACL10625.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycine catabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	aminomethyltransferase activity Inferred from electronic annotation. Source: EC transaminase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8D2P4 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 8B69D14FFC7C934C	FASTA	369	41,890
	10 20 30 40 50 60 MSRIPLLEYY IEKGAETGLF GEWEVPYRYT NAIEEHMAVR TSVGLFDVSH MGRILLKGSD 70 80 90 100 110 120 VLPFAQYIYT KDISKTKEHF MSGPMLALNQ WARVKDDEMM YKVSDEEWLL VTNALARESM 130 140 150 160 170 180 LNYFEKVKSE KGFRVEIADL TFNYSMIALQ GPRAAEVMES LGAKWAGDLK VLEFRMNEEI 190 200 210 220 230 240 HGVKTFLVSR SGWTGEDGFE IWGEHGEMRK LVDLLVSKGV KLAGLIARDT LRIEMGFVLG 250 260 270 280 290 300 GHEYGEDPVK FPCALSLRYG LGAITWEKRG FVGEEALRAC RREGVRWIRV GLKLGKEAGR 310 320 330 340 350 360 LFPRQDAGVY SDDVWVGWVT SGTYSPVLNR GIAMAYVDAR YAVFGEELAV DIRGKRYPAK IVDFPFIKK

References

[1]

"Complete genome sequence of the anaerobic, protein-degrading hyperthermophilic crenarchaeon Desulfurococcus kamchatkensis." Ravin N.V., Mardanov A.V., Beletsky A.V., Kublanov I.V., Kolganova T.V., Lebedinsky A.V., Chernyh N.A., Bonch-Osmolovskaya E.A., Skryabin K.G. J. Bacteriol. 191:2371-2379(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1221n / DSM 18924.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001140 Genomic DNA. Translation: ACL10625.1.
RefSeq	YP_002427992.1. NC_011766.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	490899.DKAM_0299.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACL10625; ACL10625; DKAM_0299.
GeneID	7170573.
KEGG	dka:DKAM_0299.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0404.
HOGENOM	HOG000239381.
KO	K00605.
OMA	WSIAWEP.
ProtClustDB	PRK00389.
Enzyme and pathway databases
BioCyc	DKAM490899:GHYH-304-MONOMER.
Family and domain databases
Gene3D	3.30.1360.120. 2 hits.
InterPro	IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. IPR027266. TrmE/GcvT_dom1. [Graphical view]
PANTHER	PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfam	PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view]
PIRSF	PIRSF006487. GcvT. 1 hit.
TIGRFAMs	TIGR00528. gcvT. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8D2P4_DESK1

Accession

Primary (citable) accession number: B8D2P4

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)