Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B8D2P4

- B8D2P4_DESK1

UniProt

B8D2P4 - B8D2P4_DESK1

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Aminomethyltransferase

Gene

DKAM_0299

Organism
Desulfurococcus kamchatkensis (strain 1221n / DSM 18924)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

The glycine cleavage system catalyzes the degradation of glycine.UniRule annotation

Catalytic activityi

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.UniRule annotation

GO - Molecular functioni

  1. aminomethyltransferase activity Source: UniProtKB-EC
  2. transaminase activity Source: UniProtKB-KW

GO - Biological processi

  1. glycine catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotation, MethyltransferaseImported, Transferase

Enzyme and pathway databases

BioCyciDKAM490899:GHYH-303-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
AminomethyltransferaseUniRule annotation (EC:2.1.2.10UniRule annotation)
Gene namesi
Ordered Locus Names:DKAM_0299Imported
OrganismiDesulfurococcus kamchatkensis (strain 1221n / DSM 18924)Imported
Taxonomic identifieri490899 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiDesulfurococcalesDesulfurococcaceaeDesulfurococcus
ProteomesiUP000006903: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: InterPro
Complete GO annotation...

Interactioni

Subunit structurei

The glycine cleavage system is composed of four proteins: P, T, L and H.UniRule annotation

Protein-protein interaction databases

STRINGi490899.DKAM_0299.

Family & Domainsi

Sequence similaritiesi

Belongs to the GcvT family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0404.
HOGENOMiHOG000239381.
KOiK00605.
OMAiPFFGVQS.

Family and domain databases

Gene3Di2.40.30.110. 1 hit.
3.30.1360.120. 2 hits.
InterProiIPR006223. GCS_T.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERiPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamiPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
PIRSFiPIRSF006487. GcvT. 1 hit.
SUPFAMiSSF101790. SSF101790. 1 hit.
TIGRFAMsiTIGR00528. gcvT. 1 hit.

Sequencei

Sequence statusi: Complete.

B8D2P4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRIPLLEYY IEKGAETGLF GEWEVPYRYT NAIEEHMAVR TSVGLFDVSH
60 70 80 90 100
MGRILLKGSD VLPFAQYIYT KDISKTKEHF MSGPMLALNQ WARVKDDEMM
110 120 130 140 150
YKVSDEEWLL VTNALARESM LNYFEKVKSE KGFRVEIADL TFNYSMIALQ
160 170 180 190 200
GPRAAEVMES LGAKWAGDLK VLEFRMNEEI HGVKTFLVSR SGWTGEDGFE
210 220 230 240 250
IWGEHGEMRK LVDLLVSKGV KLAGLIARDT LRIEMGFVLG GHEYGEDPVK
260 270 280 290 300
FPCALSLRYG LGAITWEKRG FVGEEALRAC RREGVRWIRV GLKLGKEAGR
310 320 330 340 350
LFPRQDAGVY SDDVWVGWVT SGTYSPVLNR GIAMAYVDAR YAVFGEELAV
360
DIRGKRYPAK IVDFPFIKK
Length:369
Mass (Da):41,890
Last modified:March 3, 2009 - v1
Checksum:i8B69D14FFC7C934C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001140 Genomic DNA. Translation: ACL10625.1.
RefSeqiYP_002427992.1. NC_011766.1.

Genome annotation databases

EnsemblBacteriaiACL10625; ACL10625; DKAM_0299.
GeneIDi7170573.
KEGGidka:DKAM_0299.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001140 Genomic DNA. Translation: ACL10625.1 .
RefSeqi YP_002427992.1. NC_011766.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 490899.DKAM_0299.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL10625 ; ACL10625 ; DKAM_0299 .
GeneIDi 7170573.
KEGGi dka:DKAM_0299.

Phylogenomic databases

eggNOGi COG0404.
HOGENOMi HOG000239381.
KOi K00605.
OMAi PFFGVQS.

Enzyme and pathway databases

BioCyci DKAM490899:GHYH-303-MONOMER.

Family and domain databases

Gene3Di 2.40.30.110. 1 hit.
3.30.1360.120. 2 hits.
InterProi IPR006223. GCS_T.
IPR028896. GCST/DmdA.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR029043. GcvT/YgfZ_C.
IPR027266. TrmE/GcvT_dom1.
[Graphical view ]
PANTHERi PTHR13847:SF5. PTHR13847:SF5. 1 hit.
Pfami PF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view ]
PIRSFi PIRSF006487. GcvT. 1 hit.
SUPFAMi SSF101790. SSF101790. 1 hit.
TIGRFAMsi TIGR00528. gcvT. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete genome sequence of the anaerobic, protein-degrading hyperthermophilic crenarchaeon Desulfurococcus kamchatkensis."
    Ravin N.V., Mardanov A.V., Beletsky A.V., Kublanov I.V., Kolganova T.V., Lebedinsky A.V., Chernyh N.A., Bonch-Osmolovskaya E.A., Skryabin K.G.
    J. Bacteriol. 191:2371-2379(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 1221n / DSM 18924Imported.

Entry informationi

Entry nameiB8D2P4_DESK1
AccessioniPrimary (citable) accession number: B8D2P4
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3