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B8D2P4 (B8D2P4_DESK1) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length369 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The glycine cleavage system catalyzes the degradation of glycine By similarity.

Catalytic activity

[Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3.

Subunit structure

The glycine cleavage system is composed of four proteins: P, T, L and H By similarity.

Sequence similarities

Belongs to the GcvT family. RuleBase RU003980

Ontologies

Sequences

Sequence LengthMass (Da)Tools
B8D2P4 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 8B69D14FFC7C934C

FASTA36941,890
        10         20         30         40         50         60 
MSRIPLLEYY IEKGAETGLF GEWEVPYRYT NAIEEHMAVR TSVGLFDVSH MGRILLKGSD 

        70         80         90        100        110        120 
VLPFAQYIYT KDISKTKEHF MSGPMLALNQ WARVKDDEMM YKVSDEEWLL VTNALARESM 

       130        140        150        160        170        180 
LNYFEKVKSE KGFRVEIADL TFNYSMIALQ GPRAAEVMES LGAKWAGDLK VLEFRMNEEI 

       190        200        210        220        230        240 
HGVKTFLVSR SGWTGEDGFE IWGEHGEMRK LVDLLVSKGV KLAGLIARDT LRIEMGFVLG 

       250        260        270        280        290        300 
GHEYGEDPVK FPCALSLRYG LGAITWEKRG FVGEEALRAC RREGVRWIRV GLKLGKEAGR 

       310        320        330        340        350        360 
LFPRQDAGVY SDDVWVGWVT SGTYSPVLNR GIAMAYVDAR YAVFGEELAV DIRGKRYPAK 


IVDFPFIKK 

« Hide

References

[1]"Complete genome sequence of the anaerobic, protein-degrading hyperthermophilic crenarchaeon Desulfurococcus kamchatkensis."
Ravin N.V., Mardanov A.V., Beletsky A.V., Kublanov I.V., Kolganova T.V., Lebedinsky A.V., Chernyh N.A., Bonch-Osmolovskaya E.A., Skryabin K.G.
J. Bacteriol. 191:2371-2379(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 1221n / DSM 18924.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001140 Genomic DNA. Translation: ACL10625.1.
RefSeqYP_002427992.1. NC_011766.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING490899.DKAM_0299.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL10625; ACL10625; DKAM_0299.
GeneID7170573.
KEGGdka:DKAM_0299.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0404.
HOGENOMHOG000239381.
KOK00605.
OMALGWLVHL.
ProtClustDBPRK00389.

Enzyme and pathway databases

BioCycDKAM490899:GHYH-303-MONOMER.

Family and domain databases

Gene3D3.30.1360.120. 2 hits.
InterProIPR006223. GCS_T.
IPR013977. GCV_T_C.
IPR006222. GCV_T_N.
IPR027266. TrmE/GcvT_dom1.
[Graphical view]
PANTHERPTHR13847:SF5. PTHR13847:SF5. 1 hit.
PfamPF01571. GCV_T. 1 hit.
PF08669. GCV_T_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR00528. gcvT. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8D2P4_DESK1
AccessionPrimary (citable) accession number: B8D2P4
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: March 19, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)