ID   B8D1M5_HALOH            Unreviewed;       313 AA.
AC   B8D1M5;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 56.
DE   SubName: Full=DNA polymerase LigD polymerase domain protein {ECO:0000313|EMBL:ACL69102.1};
GN   OrderedLocusNames=Hore_03410 {ECO:0000313|EMBL:ACL69102.1};
OS   Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562).
OC   Bacteria; Bacillota; Clostridia; Halanaerobiales; Halothermotrichaceae;
OC   Halothermothrix.
OX   NCBI_TaxID=373903 {ECO:0000313|EMBL:ACL69102.1, ECO:0000313|Proteomes:UP000000719};
RN   [1] {ECO:0000313|EMBL:ACL69102.1, ECO:0000313|Proteomes:UP000000719}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H 168 / OCM 544 / DSM 9562 {ECO:0000313|Proteomes:UP000000719};
RX   PubMed=19145256; DOI=10.1371/journal.pone.0004192;
RA   Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H.,
RA   Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C.;
RT   "Genome analysis of the anaerobic thermohalophilic bacterium
RT   Halothermothrix orenii.";
RL   PLoS ONE 4:E4192-E4192(2009).
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DR   EMBL; CP001098; ACL69102.1; -; Genomic_DNA.
DR   RefSeq; WP_012635290.1; NC_011899.1.
DR   AlphaFoldDB; B8D1M5; -.
DR   STRING; 373903.Hore_03410; -.
DR   KEGG; hor:Hore_03410; -.
DR   eggNOG; COG3285; Bacteria.
DR   HOGENOM; CLU_008325_1_1_9; -.
DR   OrthoDB; 9802472at2; -.
DR   Proteomes; UP000000719; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd04865; LigD_Pol_like_2; 1.
DR   Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR   InterPro; IPR014145; LigD_pol_dom.
DR   NCBIfam; TIGR02778; ligD_pol; 1.
DR   PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR   PANTHER; PTHR42705:SF2; MULTIFUNCTIONAL NON-HOMOLOGOUS END JOINING DNA REPAIR PROTEIN LIGD; 1.
DR   Pfam; PF21686; LigD_Prim-Pol; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598}; Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000719};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        293..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          26..280
FT                   /note="DNA ligase D polymerase"
FT                   /evidence="ECO:0000259|Pfam:PF21686"
SQ   SEQUENCE   313 AA;  36247 MW;  4474369312ABCCE0 CRC64;
     MKLTIGKHDV QLTNLDKVLW PELGYTKGDL INYYINMYPY LKEYLLNRPL SMKSYPDGIN
     GKSFYQKDCP DYAPHWLSTY GIFSGHRKDI INWVTINKLS DLVWVANRAS IELHTWFSTT
     TNLDKPDFAV FDLDPGSKSS MKDVVDIALT IKNILDEFNV RSFVKTSGKR GLHVYIPVKT
     RYTYKEIRSF LQNVAEMVIK LKPEQATVEW RKNKRQGKVY IDYRQNGKSK TLPAPYSLRP
     TSKATVSTPL KWSEITPDLN PDNYNIKNIE TRIKQKGNIW ETLLKIRQEL PGLFLGLLLF
     LSFSLFGGLN TFL
//