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B8D1G7 (B8D1G7_HALOH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arginine biosynthesis bifunctional protein ArgJ HAMAP MF_01106
Gene names
Name:argJ HAMAP MF_01106
Ordered Locus Names:Hore_02830
OrganismHalothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) [Complete proteome] [HAMAP]
Taxonomic identifier373903 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Halanaerobiales › Halanaerobiaceae › Halothermothrix

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate By similarity. HAMAP MF_01106

Catalytic activity

Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate. HAMAP MF_01106

N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L-glutamate. HAMAP MF_01106

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1. HAMAP MF_01106

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 1/4. HAMAP MF_01106

Subunit structure

Heterotetramer of two alpha and two beta chains By similarity. HAMAP MF_01106

Subcellular location

Cytoplasm By similarity HAMAP MF_01106.

Miscellaneous

Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway By similarity. HAMAP MF_01106

Sequence similarities

Belongs to the ArgJ family. HAMAP MF_01106

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Site190 – 1912Cleavage; by autolysis By similarity HAMAP MF_01106

Sequences

Sequence LengthMass (Da)Tools
B8D1G7 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: B34E12CC5A9754E5

FASTA40142,724
        10         20         30         40         50         60 
MSELELITGG ITAPRGFLAS GVSCGIKQEP RRDLALIYSK KAASVAGVFT TNRVQAAPVI 

        70         80         90        100        110        120 
LSRERVKGGT CRAIIVNSGN ANACTGKRGL EDARAMTARV AEGLRLNKSD VLIASTGVIG 

       130        140        150        160        170        180 
TYLPMDCIQR GIDKAISNLS DRGGSRAAEA ILTTDTCTKE IAIKGKLPSG SDYTIGGMAK 

       190        200        210        220        230        240 
GSGMIHPNMA TMLAFITTDL AILPPLLNKA LKQAVEKSFN RISVDGDQST NDSVFLIANG 

       250        260        270        280        290        300 
LSGNKPIVNC GKDYESFLKD LKEVCNYLAR KIVLDGEGAT KFVTVKVEGA YSEQDAVKVG 

       310        320        330        340        350        360 
REVANSNLVK TALFGSDPNW GRIVAAVGYS GIDIAPDLIE VTINGRTLYS RGQPWISDDI 

       370        380        390        400 
NLLSGREVVI EINLNQGEGS ATFWTTDLSH DYIKINADYH T

« Hide

References

[1]"Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii."
Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H., Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C.
PLoS ONE 4:E4192-E4192(2009) [PubMed: 19145256] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001098 Genomic DNA. Translation: ACL69044.1.
RefSeqYP_002508039.1. NC_011899.1.

3D structure databases

ProteinModelPortalB8D1G7.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8D1G7.

Protein family/group databases

MEROPST05.001.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7314669.
GenomeReviewsGene locus Hore_02830 in contig CP001098_GR.
KEGGhor:Hore_02830.
PATRIC22099828. VBIHalOre56292_0301.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284202.
OMAGRDPNWG.

Family and domain databases

HAMAPMF_01106. ArgJ.
[Tree]
InterProIPR002813. Arg_biosynth_ArgJ.
IPR016117. Pept_S58_DmpA/Arg_biosyn_ArgJ.
[Graphical view]
KOK00620.
PANTHERPTHR23100. ArgJ. 1 hit.
PfamPF01960. ArgJ. 1 hit.
[Graphical view]
ProDomPD004193. Arg_biosynth_ArgJ. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF56266. Pept_S58_DmpA/Arg_biosyn_ArgJ. 1 hit.
TIGRFAMsTIGR00120. ArgJ. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8D1G7_HALOH
AccessionPrimary (citable) accession number: B8D1G7
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info