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Protein

60 kDa chaperonin

Gene

groL

Organism
Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHORE373903:GHB1-223-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation
Ordered Locus Names:Hore_02010
OrganismiHalothermothrix orenii (strain H 168 / OCM 544 / DSM 9562)
Taxonomic identifieri373903 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaHalanaerobialesHalanaerobiaceaeHalothermothrix
Proteomesi
  • UP000000719 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001470361 – 54760 kDa chaperoninAdd BLAST547

Proteomic databases

PRIDEiB8D0Z4.

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi373903.Hore_02010.

Structurei

3D structure databases

ProteinModelPortaliB8D0Z4.
SMRiB8D0Z4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9. Bacteria.
COG0459. LUCA.
HOGENOMiHOG000076290.
KOiK04077.
OMAiCVIKVGA.
OrthoDBiPOG091H00E7.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

B8D0Z4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKELKFSED ARRALERGVD TLANAVKVTL GPKGRNVVLE KSFGAPTITN
60 70 80 90 100
DGVSIAREIE LENHYENMGA QTVKEVATKT NDVAGDGTTT ATVLAQAIFK
110 120 130 140 150
EGLKNVAAGA NPMILKRGIE KAVQKLVEEI KELSKPVEGK EAVSQVAAIS
160 170 180 190 200
AGNDEEVGKL IAEAMEKVGQ DGVISVEESK SMGTSLDVVE GMQFDRGYLS
210 220 230 240 250
PYMVTDTDAM EASLEDPYIL ITDKKISNIQ EILPLLEKVA QSGKPLLIIA
260 270 280 290 300
EDVEGEALAT LVVNKIRGTF NCVAVKAPGF GDRRKAMLED IAILTGGQVI
310 320 330 340 350
TEDLGLKLEN ADISMLGRAH KVTVTKEDTT IVEGAGDSKE IQNRIKQIRT
360 370 380 390 400
QIENTDSDFD REKLQERLAK LAGGVAVIKV GAATETELKE KKHRIEDALS
410 420 430 440 450
ATRAAVEEGL VAGGGTTLID AIPALDELNL EGDEATGVDI VRKALEAPVR
460 470 480 490 500
LIADNAGYEG SVIVEKVKSE DKGIGFDAYN GEFVNMIESG IVDPAKVTRS
510 520 530 540
ALQNAASAAA MLLTTECLVA DKEEDNDSNG NAGMPGGGMP GGMGGMM
Length:547
Mass (Da):57,966
Last modified:March 3, 2009 - v1
Checksum:i9DA0D44984016DBE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001098 Genomic DNA. Translation: ACL68963.1.
RefSeqiWP_012635161.1. NC_011899.1.

Genome annotation databases

EnsemblBacteriaiACL68963; ACL68963; Hore_02010.
KEGGihor:Hore_02010.

Similar proteinsi

Entry informationi

Entry nameiCH60_HALOH
AccessioniPrimary (citable) accession number: B8D0Z4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: November 22, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families