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B8D0Y4 (B8D0Y4_HALOH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 21. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Histidinol-phosphate aminotransferase 2 HAMAP MF_01023

EC=2.6.1.9 HAMAP MF_01023
Alternative name(s):
Imidazole acetol-phosphate transaminase 2 HAMAP MF_01023
Gene names
Name:hisC2 HAMAP MF_01023
Ordered Locus Names:Hore_01910
OrganismHalothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) [Complete proteome] [HAMAP]
Taxonomic identifier373903 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaHalanaerobialesHalanaerobiaceaeHalothermothrix

Protein attributes

Sequence length372 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861

Pathway

Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861

Subunit structure

Homodimer By similarity. HAMAP MF_01023

Sequence similarities

Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Amino acid modifications

Modified residue2341N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023

Sequences

Sequence LengthMass (Da)Tools
B8D0Y4 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 8C60A50C57A89810

FASTA37241,907
        10         20         30         40         50         60 
MLNVKRGLKS WKRIVRDEVH NIKPYIPGKP IKEVKEELGL AEVYKLASNE NPLGVSPRVK 

        70         80         90        100        110        120 
EVLTRETVNI NRYPDGASRS LKRSLSDKLG VKEDMIAIGN GSDGLLKVIA EAFLDNNSQA 

       130        140        150        160        170        180 
VISYPSFVEY KFVSQLMGTQ LIRVWMKNYH QNLEALARGV TSKTKLIFLT NPHNPAGTIF 

       190        200        210        220        230        240 
RKDELEQFLS QIPDDVIVVL DEAYHEFVQD ESYPDGIEYV KQGYPVIVLR TFSKAYGLAG 

       250        260        270        280        290        300 
LRLGYAISAP DIIETLMKVR DPFNVNHLAE KAGQAALEDK DFLEATIRNN EQGKEYLYTE 

       310        320        330        340        350        360 
LDKIGVGYVP TQANFVLIRT GVDSIKMFKE LLKHGVIVRP GKPLGYPHHL RVSIGLPEEN 

       370 
EAFIRGLKLT LE 

« Hide

References

[1]"Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii."
Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H., Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C.
PLoS ONE 4:E4192-E4192(2009) [PubMed: 19145256] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001098 Genomic DNA. Translation: ACL68953.1.
RefSeqYP_002507948.1. NC_011899.1.

3D structure databases

ProteinModelPortalB8D0Y4.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8D0Y4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7312510.
GenomeReviewsGene locus Hore_01910 in contig CP001098_GR.
KEGGhor:Hore_01910.
PATRIC22099638. VBIHalOre56292_0207.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG646350.
OMAYEYAEAE.

Family and domain databases

HAMAPMF_01023. HisC_aminotrans_2.
[Tree]
InterProIPR001176. ACC_synthase.
IPR001917. Aminotrans_II_pyridoxalP_BS.
IPR004839. Aminotransferase_I/II.
IPR005861. HisP_aminotrans.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
KOK00817.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSPR00753. ACCSYNTHASE.
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR01141. HisC. 1 hit.
PROSITEPS00599. AA_TRANSFER_CLASS_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8D0Y4_HALOH
AccessionPrimary (citable) accession number: B8D0Y4
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)