B8D0Y4 (B8D0Y4_HALOH) Unreviewed, UniProtKB/TrEMBL
Last modified
December 14, 2011.
Version 21.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Histidinol-phosphate aminotransferase 2 HAMAP MF_01023 EC=2.6.1.9 HAMAP MF_01023 Alternative name(s): Imidazole acetol-phosphate transaminase 2 HAMAP MF_01023 | ||||
| Gene names |
| ||||
| Organism | Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 373903 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Clostridia › Halanaerobiales › Halanaerobiaceae › Halothermothrix |
Protein attributes
| Sequence length | 372 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. HAMAP MF_01023 SAAS SAAS005861 |
| Cofactor | Pyridoxal phosphate By similarity. HAMAP MF_01023 SAAS SAAS005861 |
| Pathway | Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9. HAMAP MF_01023 SAAS SAAS005861 |
| Subunit structure | Homodimer By similarity. HAMAP MF_01023 |
| Sequence similarities | Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. HAMAP MF_01023 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Histidine biosynthesis HAMAP MF_01023 SAAS SAAS005861 |
| Ligand | Pyridoxal phosphate HAMAP MF_01023 SAAS SAAS005861 |
| Molecular function | Aminotransferase HAMAP MF_01023 SAAS SAAS005861 EMBL ACL68953.1 Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | histidine biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Molecular function | 1-aminocyclopropane-1-carboxylate synthase activity Inferred from electronic annotation. Source: InterPro L-phenylalanine:2-oxoglutarate aminotransferase activityInferred from electronic annotation. Source: EC histidinol-phosphate transaminase activityInferred from electronic annotation. Source: HAMAP pyridoxal phosphate bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Amino acid modifications | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Modified residue | 234 | 1 | N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01023 | ||||||
Sequences
| ||||||||||||||||||
References
| [1] | "Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii." Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H., Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C. PLoS ONE 4:E4192-E4192(2009) [PubMed: 19145256] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP001098 Genomic DNA. Translation: ACL68953.1. |
| RefSeq | YP_002507948.1. NC_011899.1. |
3D structure databases | |
| ProteinModelPortal | B8D0Y4. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | B8D0Y4. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 7312510. |
| GenomeReviews | Gene locus Hore_01910 in contig CP001098_GR. |
| KEGG | hor:Hore_01910. |
| PATRIC | 22099638. VBIHalOre56292_0207. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | HBG646350. |
| OMA | YEYAEAE. |
Family and domain databases | |
| HAMAP | MF_01023. HisC_aminotrans_2. [Tree] |
| InterPro | IPR001176. ACC_synthase. IPR001917. Aminotrans_II_pyridoxalP_BS. IPR004839. Aminotransferase_I/II. IPR005861. HisP_aminotrans. IPR015424. PyrdxlP-dep_Trfase_major_dom. IPR015421. PyrdxlP-dep_Trfase_major_sub1. IPR015422. PyrdxlP-dep_Trfase_major_sub2. [Graphical view] |
| Gene3D | G3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit. G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit. |
| KO | K00817. |
| Pfam | PF00155. Aminotran_1_2. 1 hit. [Graphical view] |
| PRINTS | PR00753. ACCSYNTHASE. |
| SUPFAM | SSF53383. PyrdxlP-dep_Trfase_major. 1 hit. |
| TIGRFAMs | TIGR01141. HisC. 1 hit. |
| PROSITE | PS00599. AA_TRANSFER_CLASS_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | B8D0Y4_HALOH | ||||||||
| Accession | Primary (citable) accession number: B8D0Y4 | ||||||||
| Entry history |
| ||||||||
| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with