B8D0F7 (B8D0F7_HALOH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphorylase RuleBase RU000587
EC=2.4.1.1 RuleBase RU000587

Gene names

Ordered Locus Names:

Hore_21480

Organism

Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) [Complete proteome] [HAMAP]

Taxonomic identifier

373903 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Halanaerobiales › Halanaerobiaceae › Halothermothrix

Protein attributes

Sequence length	535 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity. RuleBase RU000587
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. RuleBase RU000587
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000587
Sequence similarities	Belongs to the glycogen phosphorylase family. RuleBase RU004179

Ontologies

Keywords
Biological process	Carbohydrate metabolism RuleBase RU000587
Molecular function	Glycosyltransferase RuleBase RU000587 EMBL ACL70893.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8D0F7 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 74A36662D03B5E94	FASTA	535	60,833
	10 20 30 40 50 60 MEGKKPKVAY FCMEFGLHED LRIYAGGLGI LAGDILKAAR ELDVPMVGVG ILWRQGYTRQ 70 80 90 100 110 120 LIGEDGRPYD SYPTNDYIYD LVEDTGVKVK VKVRDDDIYC KVWKVDRYDN VPLYLLDTNL 130 140 150 160 170 180 PENKNKWITG QLYGWFEEER IAQEIVLGIG GVRALRKLGI DVDLYHFNDG HPVLAGTELI 190 200 210 220 230 240 NEKMAKGMSF DEALEETRKE VIFTTHTPVK EGNESHGLEV MKYMGAFNGL TLDQMIKIGD 250 260 270 280 290 300 SPFNMTVAGL RLSRIANGVS ELHGKTARKM WSYVDNKAPI VSITNGVHRK SWVDDRIVKA 310 320 330 340 350 360 YENGEDLLKP HQEIKSELID FVEEKTGTRL NPEALLIGFA RRAAPYKRGN LIFRKPEVIR 370 380 390 400 410 420 PYLEEGKIQI IFSGKAHPLD DVGKGIIADL VKMSEKYPNS VVFLEDYNIE IGRMLTRGVD 430 440 450 460 470 480 VWLNNPRRPL EASGTSGMKA AMNGALNLST LDGWWPEACE HGVNGWQLGD GYEGEDQDQH 490 500 510 520 530 DLDALYNVLL KEVVPTYYDN KEKWAQMMRA SIESTYDKFS AQRMVSRYYD EMYQN

References

[1]

"Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii." Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H., Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C. PLoS ONE 4:E4192-E4192(2009) [PubMed: 19145256] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001098 Genomic DNA. Translation: ACL70893.1.
RefSeq	YP_002509888.1. NC_011899.1.
3D structure databases
ProteinModelPortal	B8D0F7.
ModBase	Search...
Protein-protein interaction databases
STRING	B8D0F7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7313386.
GenomeReviews	Gene locus Hore_21480 in contig CP001098_GR.
KEGG	hor:Hore_21480.
PATRIC	22103900. VBIHalOre56292_2293.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG302557.
OMA	GWWPEAC.
ProtClustDB	CLSK882602.
Family and domain databases
InterPro	IPR011834. Agluc_phsphrylas. IPR000811. Glyco_trans_35. [Graphical view]
KO	K00688.
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF00343. Phosphorylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR02094. More_P_ylases. 2 hits.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8D0F7_HALOH

Accession

Primary (citable) accession number: B8D0F7

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)