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B8CZC2 (B8CZC2_HALOH) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 19. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-deoxy-manno-octulosonate cytidylyltransferase HAMAP MF_00057
EC=2.7.7.38 HAMAP MF_00057
Alternative name(s):
CMP-2-keto-3-deoxyoctulosonic acid synthase HAMAP MF_00057
Gene names
Name:kdsB HAMAP MF_00057
Ordered Locus Names:Hore_18930
OrganismHalothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) [Complete proteome] [HAMAP]
Taxonomic identifier373903 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Halanaerobiales › Halanaerobiaceae › Halothermothrix

Protein attributes

Sequence length241 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria By similarity. HAMAP MF_00057 SAAS SAAS004528

Catalytic activity

CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate. HAMAP MF_00057 SAAS SAAS004528

Pathway

Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00057 SAAS SAAS004528

Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1. HAMAP MF_00057 SAAS SAAS004528

Subcellular location

Cytoplasm By similarity HAMAP MF_00057 SAAS SAAS004528.

Sequence similarities

Belongs to the KdsB family. HAMAP MF_00057

Sequences

Sequence LengthMass (Da)Tools
B8CZC2 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 3DA92E6614A69FCE

FASTA24127,226
        10         20         30         40         50         60 
MNVIAVIPAR FYSSRFPGKP LADIKGKPMI EHVYRRVCRV KGLKEVYVAT DDDRIYNTVK 

        70         80         90        100        110        120 
DFGGNAVMTS KACSSGTDRV AEVVANLDCD IVVNVQGDEP LLEPLMVEQA LKPFAEEKNL 

       130        140        150        160        170        180 
NMSTLMKEIG DPGEVENPNV VKVVVDKDGY ALYFSRSPIP HPRNSGARYY KHIGLYIYRR 

       190        200        210        220        230        240 
KFLMNLTQME QTELEKVESL EQLRVLENGY KIKVVETEFD SIGVDTPEDI ARVEKIMEGC 


N

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References

[1]"Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii."
Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H., Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C.
PLoS ONE 4:E4192-E4192(2009) [PubMed: 19145256] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001098 Genomic DNA. Translation: ACL70641.1.
RefSeqYP_002509636.1. NC_011899.1.

3D structure databases

ProteinModelPortalB8CZC2.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8CZC2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7312708.
GenomeReviewsGene locus Hore_18930 in contig CP001098_GR.
KEGGhor:Hore_18930.
PATRIC22103336. VBIHalOre56292_2018.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG637773.
OMAINVQADE.

Family and domain databases

HAMAPMF_00057. CMP_KDO_synth.
[Tree]
InterProIPR003329. Cytidylyl_trans.
IPR004528. KdsB.
[Graphical view]
KOK00979.
PANTHERPTHR21485:SF4. PTHR21485:SF4. 1 hit.
PfamPF02348. CTP_transf_3. 1 hit.
[Graphical view]
TIGRFAMsTIGR00466. KdsB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8CZC2_HALOH
AccessionPrimary (citable) accession number: B8CZC2
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 19 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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