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B8CWW9 (B8CWW9_HALOH) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonuclease 3 HAMAP-Rule MF_00104
EC=3.1.26.3 HAMAP-Rule MF_00104
Alternative name(s):
Ribonuclease III HAMAP-Rule MF_00104
Gene names
Name:rnc HAMAP-Rule MF_00104
Ordered Locus Names:Hore_10320
OrganismHalothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) [Complete proteome] [HAMAP]
Taxonomic identifier373903 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Clostridia › Halanaerobiales › Halanaerobiaceae › Halothermothrix ›

Protein attributes

Sequence length236 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104 SAAS SAAS001159

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104 SAAS SAAS000999

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104 SAAS SAAS001159

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104 SAAS SAAS001159.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain. HAMAP-Rule MF_00104 SAAS SAAS001159

Contains 1 RNase III domain. HAMAP-Rule MF_00104 SAAS SAAS001159

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain10 – 139130RNase III By similarity HAMAP-Rule MF_00104
Domain166 – 23570DRBM By similarity HAMAP-Rule MF_00104

Sites

Active site561 By similarity HAMAP-Rule MF_00104
Active site1281 By similarity HAMAP-Rule MF_00104
Metal binding521Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1251Magnesium By similarity HAMAP-Rule MF_00104
Metal binding1281Magnesium By similarity HAMAP-Rule MF_00104

Sequences

Sequence LengthMass (Da)Tools
B8CWW9 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 1FE157506702AD8D

FASTA23626,854
        10         20         30         40         50         60 
MIRIYNKKLL KKLEEKLNIR FNDISLLQKA VTHKSFVHEK SDPDLEDNER LEFLGDSVLS 

        70         80         90        100        110        120 
IVISTYLYKN FPEYNEGELA KMRAYIVSSS HLACKARELG LGKYILMGKG EELNGGRERE 

       130        140        150        160        170        180 
SILADTLEAV IGAIYLDQGF NTITDLLINF FKDDVKKLDQ GNIIRDYKTY LQEFIQKDGS 

       190        200        210        220        230 
CEIKYNIINE YGPDHNKKFE VGVKVNGKEL GRGTGFSKKE AEQKAAKDAL SNLGEI

« Hide

References

[1]"Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii."
Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H., Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C.
PLoS ONE 4:E4192-E4192(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: H 168 / OCM 544 / DSM 9562.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001098 Genomic DNA. Translation: ACL69788.1.
RefSeqYP_002508783.1. NC_011899.1.

3D structure databases

ProteinModelPortalB8CWW9.
ModBaseSearch...

Protein-protein interaction databases

STRING373903.Hore_10320.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL69788; ACL69788; Hore_10320.
GeneID7314620.
KEGGhor:Hore_10320.
PATRIC22101462. VBIHalOre56292_1097.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0571.
HOGENOMHOG000246808.
KOK03685.
OMALTHKSCK.
ProtClustDBCLSK2806360.

Enzyme and pathway databases

BioCycHORE373903:GHB1-1077-MONOMER.

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR001159. Ds-RNA-bd.
IPR014720. dsRNA-bd-like_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. RNase_III. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8CWW9_HALOH
AccessionPrimary (citable) accession number: B8CWW9
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info