B8CWW7 (B8CWW7_HALOH) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acyl carrier protein HAMAP MF_01217
Short name=ACP HAMAP MF_01217

Gene names

Name:	acpP HAMAP MF_01217
Ordered Locus Names:	Hore_10300

Organism

Halothermothrix orenii (strain H 168 / OCM 544 / DSM 9562) [Complete proteome] [HAMAP]

Taxonomic identifier

373903 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Halanaerobiales › Halanaerobiaceae › Halothermothrix

Protein attributes

Sequence length	78 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Carrier of the growing fatty acid chain in fatty acid biosynthesis By similarity. HAMAP MF_01217
Pathway	Lipid metabolism; fatty acid biosynthesis. HAMAP MF_01217
Subcellular location	Cytoplasm By similarity HAMAP MF_01217.
Post-translational modification	4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group By similarity. HAMAP MF_01217 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS By similarity. RuleBase RU003545
Sequence similarities	Contains 1 acyl carrier domain. HAMAP MF_01217 RuleBase RU003545

Ontologies

Keywords
Biological process	Fatty acid biosynthesis HAMAP MF_01217 Lipid synthesis
Cellular component	Cytoplasm HAMAP MF_01217
Ligand	Phosphopantetheine HAMAP MF_01217 RuleBase RU003545
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fatty acid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	acyl carrier activity Inferred from electronic annotation. Source: HAMAP cofactor binding Inferred from electronic annotation. Source: InterPro phosphopantetheine binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Amino acid modifications
	Modified residue	38	1	O-(pantetheine 4'-phosphoryl)serine By similarity HAMAP MF_01217

Sequences

	Sequence		Length	Mass (Da)
	B8CWW7 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 74EFF6112AE2E9D3	FASTA	78	8,644
	10 20 30 40 50 60 MVDNTLEKVV DIVVEELGVD PDEVTPEASF IDDLGADSLD VVELVMAFEE EFGIEIPDED 70 AENIETVQDA VDYIEENL

References

[1]

"Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii." Mavromatis K., Ivanova N., Anderson I., Lykidis A., Hooper S.D., Sun H., Kunin V., Lapidus A., Hugenholtz P., Patel B., Kyrpides N.C. PLoS ONE 4:E4192-E4192(2009) [PubMed: 19145256] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001098 Genomic DNA. Translation: ACL69786.1.
RefSeq	YP_002508781.1. NC_011899.1.
3D structure databases
ProteinModelPortal	B8CWW7.
SMR	B8CWW7. Positions 7-78.
ModBase	Search...
Protein-protein interaction databases
STRING	B8CWW7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7314618.
GenomeReviews	Gene locus Hore_10300 in contig CP001098_GR.
KEGG	hor:Hore_10300.
PATRIC	22101458. VBIHalOre56292_1095.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG755218.
OMA	PESRFTE.
Family and domain databases
HAMAP	MF_01217. Acyl_carrier. [Tree]
InterPro	IPR003231. Acyl_carrier. IPR009081. Acyl_carrier_prot-like. IPR006163. Phsphopanteth-bd. IPR006162. PPantetheine_attach_site. [Graphical view]
Gene3D	G3DSA:1.10.1200.10. ACP_like. 1 hit.
KO	K02078.
Pfam	PF00550. PP-binding. 1 hit. [Graphical view]
ProDom	PD000887. PD000887. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF47336. ACP_like. 1 hit.
TIGRFAMs	TIGR00517. Acyl_carrier. 1 hit.
PROSITE	PS50075. ACP_DOMAIN. 1 hit. PS00012. PHOSPHOPANTETHEINE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8CWW7_HALOH

Accession

Primary (citable) accession number: B8CWW7

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)