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B8CR70

- SPEA_SHEPW

UniProt

B8CR70 - SPEA_SHEPW

Protein

Biosynthetic arginine decarboxylase

Gene

speA

Organism
Shewanella piezotolerans (strain WP3 / JCM 13877)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Catalyzes the biosynthesis of agmatine from arginine.UniRule annotation

    Catalytic activityi

    L-arginine = agmatine + CO2.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation
    Pyridoxal phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. arginine decarboxylase activity Source: UniProtKB-HAMAP
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. arginine catabolic process Source: InterPro
    2. spermidine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Polyamine biosynthesis, Spermidine biosynthesis

    Keywords - Ligandi

    Magnesium, Metal-binding, Pyridoxal phosphate

    Enzyme and pathway databases

    BioCyciSPIE225849:GH6V-2958-MONOMER.
    UniPathwayiUPA00186; UER00284.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Biosynthetic arginine decarboxylaseUniRule annotation (EC:4.1.1.19UniRule annotation)
    Short name:
    ADCUniRule annotation
    Gene namesi
    Name:speAUniRule annotation
    Ordered Locus Names:swp_3024
    OrganismiShewanella piezotolerans (strain WP3 / JCM 13877)
    Taxonomic identifieri225849 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
    ProteomesiUP000000753: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 637637Biosynthetic arginine decarboxylasePRO_1000145603Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei101 – 1011N6-(pyridoxal phosphate)lysineUniRule annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi225849.swp_3024.

    Structurei

    3D structure databases

    ProteinModelPortaliB8CR70.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni286 – 29611Substrate-bindingUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1166.
    HOGENOMiHOG000029191.
    KOiK01585.
    OMAiIDHYVDG.
    OrthoDBiEOG676Z0R.

    Family and domain databases

    Gene3Di2.40.37.10. 2 hits.
    3.20.20.10. 1 hit.
    HAMAPiMF_01417. SpeA.
    InterProiIPR009006. Ala_racemase/Decarboxylase_C.
    IPR002985. Arg_decrbxlase.
    IPR022643. De-COase2_C.
    IPR022644. De-COase2_N.
    IPR000183. Orn/DAP/Arg_de-COase.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF02784. Orn_Arg_deC_N. 1 hit.
    PF00278. Orn_DAP_Arg_deC. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001336. Arg_decrbxlase. 1 hit.
    PRINTSiPR01180. ARGDCRBXLASE.
    PR01179. ODADCRBXLASE.
    SUPFAMiSSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR01273. speA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B8CR70-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNNWSIDDAR ASYNVNYWSQ GLYGISDEGE VTVSPDPNRP DCKIGLNELA    50
    KDMVKAGVAL PVLVRFPQIL HHRVNSLCQA FNQAIQKYKY EADYLLVYPI 100
    KVNQQQTVVE EILASQVEKE VPQLGLEAGS KPELLAVLAM AQKASSVIIC 150
    NGYKDKEYIR LALIGEKLGH KVYIVLEKMS ELKVVLEQAK ELGVTPRLGL 200
    RVRLAFQGKG KWQASGGEKS KFGLSAAQVL KVIELLQHEE MLDSLELLHF 250
    HLGSQIANIR DIRQGVSEAG RFYCELMKLG AQVKCFDVGG GLAVDYDGTR 300
    SQSNNSMNYG LTEYANNIVS VLTDMCKEYE QPMPRIISES GRYLTAHHAV 350
    LLTDVIGTES YKPETILPPS EDAPLLLQNM WQSWTEVSGK ADQRALIEIF 400
    HDCQSDLTEV HSLFALGQLS LADRAWAEQI NLRVCHELQG SMSSKYRYHR 450
    PIIDELNEKL ADKFFVNFSL FQSLPDAWGI DQVFPVMPLS GLDKAPERRA 500
    VMLDITCDSD GIVDQYVDGQ GIETTLPVPA WTQESPYLIG FFLVGAYQEI 550
    LGDMHNLFGD TNSAVVRVDE NGRRNIDSVL EGDTVADVLR YVNLEAVSFM 600
    RTYEELVNKH IVADERSNIL EELQLGLKGY TYLEDFS 637
    Length:637
    Mass (Da):71,415
    Last modified:March 3, 2009 - v1
    Checksum:i049210A3D93B1F27
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000472 Genomic DNA. Translation: ACJ29742.1.
    RefSeqiYP_002312329.1. NC_011566.1.

    Genome annotation databases

    EnsemblBacteriaiACJ29742; ACJ29742; swp_3024.
    GeneIDi7034027.
    KEGGiswp:swp_3024.
    PATRICi23544528. VBIShePie65056_2780.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000472 Genomic DNA. Translation: ACJ29742.1 .
    RefSeqi YP_002312329.1. NC_011566.1.

    3D structure databases

    ProteinModelPortali B8CR70.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 225849.swp_3024.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACJ29742 ; ACJ29742 ; swp_3024 .
    GeneIDi 7034027.
    KEGGi swp:swp_3024.
    PATRICi 23544528. VBIShePie65056_2780.

    Phylogenomic databases

    eggNOGi COG1166.
    HOGENOMi HOG000029191.
    KOi K01585.
    OMAi IDHYVDG.
    OrthoDBi EOG676Z0R.

    Enzyme and pathway databases

    UniPathwayi UPA00186 ; UER00284 .
    BioCyci SPIE225849:GH6V-2958-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 2 hits.
    3.20.20.10. 1 hit.
    HAMAPi MF_01417. SpeA.
    InterProi IPR009006. Ala_racemase/Decarboxylase_C.
    IPR002985. Arg_decrbxlase.
    IPR022643. De-COase2_C.
    IPR022644. De-COase2_N.
    IPR000183. Orn/DAP/Arg_de-COase.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF02784. Orn_Arg_deC_N. 1 hit.
    PF00278. Orn_DAP_Arg_deC. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001336. Arg_decrbxlase. 1 hit.
    PRINTSi PR01180. ARGDCRBXLASE.
    PR01179. ODADCRBXLASE.
    SUPFAMi SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR01273. speA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3."
      Wang F., Wang J., Jian H., Zhang B., Li S., Wang F., Zeng X., Gao L., Bartlett D.H., Yu J., Hu S., Xiao X.
      PLoS ONE 3:E1937-E1937(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: WP3 / JCM 13877.

    Entry informationi

    Entry nameiSPEA_SHEPW
    AccessioniPrimary (citable) accession number: B8CR70
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3