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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene

aat

Organism
Shewanella piezotolerans (strain WP3 / JCM 13877)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-lysyl-[protein].UniRule annotation
L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = tRNA(Leu) + N-terminal L-leucyl-L-arginyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BioCyciSPIE225849:G1G7F-1686-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotation (EC:2.3.2.6UniRule annotation)
Alternative name(s):
L/F-transferaseUniRule annotation
LeucyltransferaseUniRule annotation
PhenyalanyltransferaseUniRule annotation
Gene namesi
Name:aatUniRule annotation
Ordered Locus Names:swp_1874
OrganismiShewanella piezotolerans (strain WP3 / JCM 13877)
Taxonomic identifieri225849 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella
Proteomesi
  • UP000000753 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001319521 – 236Leucyl/phenylalanyl-tRNA--protein transferaseAdd BLAST236

Interactioni

Protein-protein interaction databases

STRINGi225849.swp_1874

Structurei

3D structure databases

SMRiB8CLI5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108R4Z Bacteria
COG2360 LUCA
HOGENOMiHOG000102325
KOiK00684
OMAiYRQGIFP
OrthoDBiPOG091H045I

Family and domain databases

HAMAPiMF_00688 Leu_Phe_trans, 1 hit
InterProiView protein in InterPro
IPR016181 Acyl_CoA_acyltransferase
IPR004616 Leu/Phe-tRNA_Trfase
PANTHERiPTHR30098 PTHR30098, 1 hit
PfamiView protein in Pfam
PF03588 Leu_Phe_trans, 1 hit
SUPFAMiSSF55729 SSF55729, 1 hit
TIGRFAMsiTIGR00667 aat, 1 hit

Sequencei

Sequence statusi: Complete.

B8CLI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSLSYLNQD QQSFPPPEQA LSDPNGLLAV GGDLQPERLL NAYYNGIFPW
60 70 80 90 100
FNQDDPILWW SPDPRAVFAP GNLRVSRSLI KYLKKQSWTF SINKQFPAVI
110 120 130 140 150
RGCAAPRAKQ EETWISDDIQ QAYLSLHQQG HAHSIEVWED DILIGGLYGL
160 170 180 190 200
AIGQVFCGES MFHLRTNASK AAMIVLQQHL LRCGFKLIDA QVENPHLDSL
210 220 230
GAKSIKRKDF LTLLKHLRDG DVNPDSWLTT EVPIEL
Length:236
Mass (Da):26,664
Last modified:March 3, 2009 - v1
Checksum:iAB9888827AF70621
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000472 Genomic DNA Translation: ACJ28636.1
RefSeqiWP_020912012.1, NC_011566.1

Genome annotation databases

EnsemblBacteriaiACJ28636; ACJ28636; swp_1874
KEGGiswp:swp_1874

Similar proteinsi

Entry informationi

Entry nameiLFTR_SHEPW
AccessioniPrimary (citable) accession number: B8CLI5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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